Vaccination against COVID-19 is associated with reduced heart rate.

Published Date: 02 Mar 2023

Even partial vaccinations have been associated with fewer people becoming infected with COVID-19 in observational studies, although more research is needed on the spread of new and emerging diseases.

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Enhancing Quality of Life for Terminally Ill Veterans

Honoring individualized preferences for end-of-life interventions for veterans is a priority for families and caregivers; this study explores various nonpharmacologic interventions.

US FDA Extends Review Of Exelixis' Cancer Drug

The U.S. Food and Drug Administration has extended the review of Exelixis' experimental colorectal cancer drug combination ⁠by three months, the company said in a filing on...

CDC Issues Alert on Rabies Exposure, Appropriate Treatment

The agency expresses concern that a rise in use of postexposure prophylaxis could indicate a lack of understanding of when to administer the therapy.

Backlogs, Testing Gaps in Medicare AI Prior Auth Pilot

Internal documents show contractor readiness concerns, decision delays, and high non-affirmation rates, while providers report patients waiting for care and payment problems.

Mycobacteria Linked to Worse Lung Transplant Outcomes

In lung transplant recipients, detecting nontuberculous mycobacteria in the first year after a transplant may signal heightened risks for death or a repeat transplant and for chronic graft decline.

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First-Line T-DXd Boosts PFS in HER2-Mutant NSCLC

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A European Parliament committee is backing employer risk assessments to tackle burnout. But should that mean new binding EU rules?

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FET-PET Agent Approved for Glioma Imaging

Floretyrosine F18 is the first amino acid PET imaging agent approved for glioma in the United States.

Todays Updates

First-Line T-DXd Boosts PFS in HER2-Mutant NSCLC

DESTINY-Lung04 supports trastuzumab deruxtecan as a new frontline option for patients with advanced HER2-mutant disease, though it failed to improve overall survival.

Could Burnout Become the Employer’s Responsibility?

A European Parliament committee is backing employer risk assessments to tackle burnout. But should that mean new binding EU rules?

High CLL Remission Seen With First-Line Triplet Regimen

High 2-year survival rates are seen in treatment-naive patients with CLL receiving a noncovalent BTK inhibitor combined with venetoclax and obinutuzumab.

FET-PET Agent Approved for Glioma Imaging

Floretyrosine F18 is the first amino acid PET imaging agent approved for glioma in the United States.

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Honoring individualized preferences for end-of-life interventions for veterans is a priority for families and caregivers; this study explores various nonpharmacologic interventions.

The U.S. Food and Drug Administration has extended the review of Exelixis' experimental colorectal cancer drug combination ⁠by three months, the company said in a filing on...

The agency expresses concern that a rise in use of postexposure prophylaxis could indicate a lack of understanding of when to administer the therapy.

Internal documents show contractor readiness concerns, decision delays, and high non-affirmation rates, while providers report patients waiting for care and payment problems.

In lung transplant recipients, detecting nontuberculous mycobacteria in the first year after a transplant may signal heightened risks for death or a repeat transplant and for chronic graft decline.

An expert consensus panel has offered the first-ever standardized, evidence-based recommendations for the management of alopecia areata, identifying JAK inhibitors as the first-line therapy.

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Does Humor Have a Place in Modern Medicine?

Medical anecdotes show how wit, empathy, and communication can shape clinical encounters, offering a glimpse into human experiences that unfold beyond diagnosis and treatment.

Genetic Testing Before Prescribing: Routine or Selective?

Pharmacogenetic testing can inform medication choice and adverse effect risk, while questions remain about implementation, data storage, and access in routine care.

PTCy Shows Promise for Mismatched Donor Transplants

A phase 2 trial evaluates whether posttransplant cyclophosphamide can support the use of mismatched unrelated donor transplants in patients needing reduced-intensity or non-myeloablative conditioning.

Memantine May Help Improve Cognition in Patients With SLE

Treatment with memantine may help improve cognitive function in patients with systemic lupus erythematosus and neuropsychological deficits, a phase 2 study finds.

Dupilumab Improves Lung Function in Asthma and ABPA

Dupilumab improves lung function and reduces corticosteroid dependence in patients with asthma and allergic bronchopulmonary aspergillosis compared with placebo, a phase 2 trial finds.

When It’s Really Hot: What Mental Health Risks Are Missed?

Extreme heat can worsen psychiatric symptoms and disrupt sleep, whereas some medications may increase vulnerability to dehydration, heat illness, and toxicity.

ANCA Vasculitides Tied to Higher Cardiovascular Event Risk

Both granulomatosis with polyangiitis and microscopic polyangiitis are associated with an increased risk for cardiovascular and thromboembolic events.

Metabolic Conditions Common in Chronic Rhinosinusitis

Overweight or obesity, hypertension, and diabetes are common in patients with chronic rhinosinusitis, but their prevalence is similar to global reference estimates, a meta-analysis finds.

Health Rounds: AstraZeneca Drug Reduces Lung Disease Flare-ups in Late-stage Trials

(This is an excerpt of the Health Rounds newsletter, where we present latest medical studies on Tuesdays and Thursdays.)

NHS Urged to Scrap 'Outdated' Transplant Rule

Blood cancer charities want NHS England’s blanket rule on second stem cell transplants changed to reflect modern practice and opinion.

Horse Smuggling Exposes Cracks in US Defenses Against Screwworm

When sheriff's deputies intercepted a trailer carrying six horses near the border town of Redford, Texas, they uncovered more than a livestock violation. The animals had...

Guidelines Conflict: How Hospitalists Decide at the Bedside

‘Medicine shines through’ when evidence-based medicine isn’t enough.

MRSA Prevention Program Cuts Hospital-Onset Bacteremia

An educational quality improvement program significantly reduces hospital-onset methicillin-resistant Staphylococcus aureus bacteremia events across all the participating hospital units.

Urine Culture Can Speed Urosepsis Pathogen Detection

In suspected urosepsis, urine culture matched the pathogen found in blood culture in 54.6% of episodes while delivering results faster, potentially enabling earlier targeted antimicrobial therapy.

Ex-Health Minister: Time to Rebuild Mental Healthcare

Mental health campaigner Sir Norman Lamb sets out the four questions he thinks the NHS must answer to fix mental healthcare.

We Might Have Been Wrong About How the Immune System Ages

A rare immune cell linked to cancer resistance increases in the very old, suggesting the immune system actively adapts to extreme longevity.

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