‘Too Good to Be True?’ GLP-1s and Breast Cancer Survival

Published Date: 13 May 2026

Dr F. Perry Wilson breaks down study findings suggesting a link between GLP-1 drugs and improved outcomes among patients with breast cancer and obesity.

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PSA-Discordant Progression in Metastatic Prostate Cancer

Rare squamous transformation in metastatic prostate cancer caused disease progression despite suppressed PSA, found only through re-biopsy.

Alcohol's Heart Benefit Was a Statistical Illusion

No dose of alcohol is risk-free, and none protects the heart. It's time to counsel patients on drinking less rather than where the line sits.

A Woman on Ruxolitinib Had TB That Mimicked Metastases

A woman receiving ruxolitinib for polycythemia vera developed disseminated tuberculosis despite a negative IGRA, highlighting the limits of screening.

Pediatric Gastroenterology Faces AI Reality Check

From nutrition screening to IBD monitoring, AI shows promise in pediatric gastroenterology — yet experts stress pediatric validation is essential.

Hidradenitis Suppurativa–Associated Squamous Cell Carcinoma

Four cases highlight the aggressive nature of cutaneous squamous cell carcinoma arising in chronic perianal and gluteal hidradenitis suppurativa.

FDA Neurology Digest: August 2026

A monthly snapshot of FDA activity involving therapies used in the prevention, diagnosis, and treatment of neurologic conditions.

Todays Updates

Sevabertinib Approved for First-Line Mutated NSCLC

The oral HER2 TKI was previously given accelerated approval in the second line for the indication.

Todays Updates

Sevabertinib Approved for First-Line Mutated NSCLC

The oral HER2 TKI was previously given accelerated approval in the second line for the indication.

Latest News

Rare squamous transformation in metastatic prostate cancer caused disease progression despite suppressed PSA, found only through re-biopsy.

No dose of alcohol is risk-free, and none protects the heart. It's time to counsel patients on drinking less rather than where the line sits.

A woman receiving ruxolitinib for polycythemia vera developed disseminated tuberculosis despite a negative IGRA, highlighting the limits of screening.

From nutrition screening to IBD monitoring, AI shows promise in pediatric gastroenterology — yet experts stress pediatric validation is essential.

Four cases highlight the aggressive nature of cutaneous squamous cell carcinoma arising in chronic perianal and gluteal hidradenitis suppurativa.

A monthly snapshot of FDA activity involving therapies used in the prevention, diagnosis, and treatment of neurologic conditions.

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Teen With a Slowly Enlarging Annular Hyperkeratotic Papule

The lesion initially appeared as a small papule and gradually enlarged, with more noticeable growth in recent months. The lesion was not painful, pruritic, or bleeding.

Thyroid Surgery: Practical Strategies for Optimal Post-op Care

Drs Kaniksha Desai and Michael Yeh discuss practical aspects of postoperative thyroid surgery care.

What's Driving Pancreatic Cancer Risk?

From modifiable habits to genetic red flags, here's what raises pancreatic cancer risk, and when to screen for it.

Rapid Genetic Screening May Protect Newborn Hearing

A rapid bedside genetic test may help neonatologists avoid gentamicin-related hearing loss in newborns at the highest risk.

Early Breast Cancer: Time to Act on Molecular Resistance?

In breast cancer, molecular resistance can precede clinical progression, but should it prompt an immediate change in treatment?

Punch Biopsy Techniques Every PCP Should Know

Performing a punch biopsy doesn't have to be daunting. Learn the essential steps every PCP needs to confidently sample, suture, and care for biopsy sites.

Risk Assessment of Thyroid Nodules: A Practical Guide

Most thyroid nodules are benign, but risk stratification matters. Learn how ultrasound, TI-RADS, and postbiopsy tools guide smarter referral decisions.

A PCP’s Guide to Tangential Shave Biopsy

Learn how to perform a tangential shave biopsy with confidence. This step-by-step guide walks PCPs through the essential technique for sampling skin lesions and tumors.

Four Signs You Should Biopsy a Skin Lesion, Not Freeze It

Before you freeze a skin lesion, ask yourself whether you really know what it is. Here are four signs you should biopsy instead of freeze.

BRCA Testing Shifts From Late Data to Urgent Priority

BRCA testing now guides urgent treatment decisions as well as family risk assessment, and Spanish experts highlight its implications for PARP inhibitors, oncofertility, liquid biopsy, and exercise.

Wet Age-Related Macular Degeneration Updates From ASRS 2026

Updates in wet AMD from ASRS 2026 include real-world data on anti-VEGF treatment persistence, ELARA data on aflibercept 8 mg, as well as two studies showing reduced injection burden via gene therapy.

Stop Assuming Every Thick, Yellow Nail Is Fungus

Treating toenail fungus without confirming the diagnosis is a common mistake. Here's how to confirm it, treat it, and know what to expect.

Trust Me — I'm a Podcaster

Public trust in institutions has waned but patients trust their personal doctors. Clinicians can be influencers without TikTok or a podcast writes this podcasting cardiologist.

Erythematous Infiltrated Papules and Plaques on the Forehead

A 32-year-old woman presented to the dermatology department with asymptomatic raised, reddish lesions on the right forehead of 5 months’ duration.

S3 Episode 6: Epidemiology of Endometrial Cancer

Drs Ursula A. Matulonis and Immaculata De Vivo discuss the epidemiology of endometrial cancer and how clinicians can use information about risk factors.