Studies have shown that neoadjuvant nivolumab may provide long-term benefits for people with non-small cell lung cancer.

Published Date: 17 Feb 2023

BACKGROUND: NSCLC is the most common and important cause of cancer worldwide. Assessment: The patient...

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Light Activity Pays Off for COPD Survival

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Initial Prescription Duration May Shape Benzodiazepine Use

Longer durations of initial prescriptions are associated with prolonged use of benzodiazepines compared with durations of 7 days or less, a large cohort study shows.

Alcohol’s Health Myth Is Over. How to Tell Patients

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US House Committee Opens Investigation Into Merck, AbbVie China Drug Trials

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Real-World EV Plus Pembro Success Seen in Urothelial Cancer

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Germline Variants Predict Lobular Breast Cancer Recurrence

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MRI Enhancement Predicts Breast Cancer in BRCA Carriers

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Polatuzumab Vedotin Boosts Survival in Relapsed DLBCL

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Real-World EV Plus Pembro Success Seen in Urothelial Cancer

A retrospective study evaluates outcomes associated with first-line enfortumab vedotin plus pembrolizumab vs gemcitabine plus cisplatin in patients with metastatic urothelial carcinoma.

Germline Variants Predict Lobular Breast Cancer Recurrence

For women with invasive lobular carcinoma, pathogenic variants in breast cancer risk genes predict high odds of early recurrence.

MRI Enhancement Predicts Breast Cancer in BRCA Carriers

Higher background parenchymal enhancement on breast MRI may signal greater risk among women who carry BRCA mutations.

Polatuzumab Vedotin Boosts Survival in Relapsed DLBCL

Patients with relapsed or refractory diffuse large B-cell lymphoma, who were ineligible for autologous stem cell transplant, were randomly assigned to receive Pola-R-GemOx or R-GemOx.

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New data show that patients need not exercise intensely to improve outcomes.

Longer durations of initial prescriptions are associated with prolonged use of benzodiazepines compared with durations of 7 days or less, a large cohort study shows.

The science on alcohol has changed dramatically. Here’s how experts say physicians can explain why older advice no longer holds up — and counsel patients without judgment.

The chair of the U.S. House Select Committee on China opened national security investigations into whether five drugmakers including Merck and AbbVie have been involved in...

In patients with chronic hepatitis B infection, bepirovirsen achieves significantly higher rates of functional cure than placebo after discontinuation of nucleoside or nucleotide analog therapy.

Many adults with diabetes have uncontrolled or previously undiagnosed high blood pressure during their routine visits to retina clinics, prompting referrals and urgent follow-up, a study finds.

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Wrist Air Samplers Detect Virus Exposure in Kids With Asthma

Devices may inform disease prevention strategies by providing community-level data.

Colistin MIC Affects Outcomes in Gram-Negative Infections

In carbapenem-resistant gram-negative infections caused by pathogens for which the colistin MIC is 2 mg/L, the colistin-meropenem combination is linked to better clinical outcomes than colistin alone.

What 300,000 Implants Say About Light Adjustable Lens

An intraocular lens that can be adjusted after cataract surgery has better outcomes for meeting target vision than other lenses, but patient selection and involvement are key.

Parkinson’s Disease Deaths Decline Among Older US Adults

Death rates from Parkinson’s disease among US older adults decline in 2024 following a steady rise from 2014 to 2021, new data show.

Sri Lanka Battles Surge in Dengue Fever, With More Than 44,000 Cases So Far This Year

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More Than 70 Congo Medics Infected With Ebola Since Outbreak Started, WHO Says

A senior World Health Organization official said on Friday that 75 ⁠medics in the Democratic Republic of Congo had been infected with Ebola and 17 of ⁠them had died since...

US Progesterone Supplies Tighten as Menopause Treatment Demand Grows

U.S. supplies of progesterone are coming under strain, with patients, clinicians, and pharmacists reporting recent intermittent shortages of oral versions of the hormone...

Moderna's MRNA Flu Vaccine Backed by FDA Advisers

Advisers to the U.S. Food and Drug Administration on Thursday backed approval of Moderna's flu vaccine for adults aged 50 and older, saying its benefits outweigh its risks,...

Mycobacteria May Predict Graft Failure After Lung Transplant

Early isolation can be a biomarker for patients at increased risk for poor outcomes.

Safety Gaps Put Patients at Risk Across NHS Pathways

NHS patients may face delays in accessing specialist care because of accountability failures and data-sharing gaps across regional pathways, HSSIB has warned.

Moderna Flu Shot Data May Support Use in Older Adults, US FDA Staff Says

U.S. Food and Drug Administration staff reviewers said on Tuesday data demonstrating an immune response to Moderna's flu shot may support effectiveness in adults ⁠65 years...

Ebola Risk for World Cup Is 'Extremely Low', but US Is Ready, Experts Say

The risk that a traveler infected with Ebola could arrive in the United States during the 2026 World Cup tournament that kicked off last week is low but not zero, and if...

US Paying Almost $25,000 a Month to Store Unusable Contraceptives Stuck in Belgium

The United States is spending almost $25,000 every month to store contraceptives in Belgium that were originally bought for use in poorer nations but are ⁠now mainly...

RCPsych: Make Mental Healthcare a Priority, Not a Privilege

The UK must choose between investing in mental healthcare for all or accepting a postcode lottery, the outgoing RCPsych president warns.

VR May Help Curb Cravings in Substance Use Disorder

Virtual reality-based interventions are associated with significantly reduced cravings in patients with various substance use disorders, a new meta-analysis shows.

Infections Tied to Asthma Attacks on Benralizumab Therapy

In patients with eosinophilic asthma on benralizumab, attacks often feature airway neutrophilia, respiratory viruses, and microbiome shifts, indicating infections are a key cause of exacerbations.

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