Studies have shown that neoadjuvant nivolumab may provide long-term benefits for people with non-small cell lung cancer.

Published Date: 17 Feb 2023

BACKGROUND: NSCLC is the most common and important cause of cancer worldwide. Assessment: The patient...

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Proteinuria Remission Predicts Outcomes in Pediatric IgAN

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BRCA Mutation Carriers Likely to Have Risk-Reducing Surgery

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Ketamine Infusions Shows Benefit in Bipolar Depression

Adjunctive serial IV ketamine infusions significantly reduced depressive symptoms in TRBD, with no cases of mania, hypomania, or psychosis observed in the randomized trial.

Digital Pillbox Boosts Short-Term Viral Control in Young PWH

A digital pillbox with medication reminders and adherence feedback improves viral suppression in young people with HIV over 6 months, a trial finds.

Distinct Risk Factor Profiles Tied to Endometriosis Subtypes

Various factors such as menstrual history, pain conditions, and immune disorders are distinctly tied to endometriosis lesion types — superficial lesions, ovarian cysts, and deep lesions.

Todays Updates

Bilateral Mastectomy Rises in Young BRCA1/2 Carriers

Among young women with BRCA1/2 mutations and breast cancer, bilateral mastectomy rates increased substantially from 2000 to 2020.

Proteinuria Remission Predicts Outcomes in Pediatric IgAN

Children with IgA nephropathy who achieve sustained proteinuria remission have significantly better long-term kidney function over 5 years than those who do not.

BRCA Mutation Carriers Likely to Have Risk-Reducing Surgery

Researchers conduct a study of about 4000 women with pathogenic variants in at least one of 13 breast cancer susceptibility genes to see their utilization of cancer risk-reducing procedures.

Once-Nightly Eye Drop Aids Dim-Light Vision

In patients who face difficulty seeing in low light, a once-nightly eye drop significantly improves night vision and reduces glare, halos, and starbursts, a phase 3 trial shows.

Ketamine Infusions Shows Benefit in Bipolar Depression

Adjunctive serial IV ketamine infusions significantly reduced depressive symptoms in TRBD, with no cases of mania, hypomania, or psychosis observed in the randomized trial.

Digital Pillbox Boosts Short-Term Viral Control in Young PWH

A digital pillbox with medication reminders and adherence feedback improves viral suppression in young people with HIV over 6 months, a trial finds.

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Latest News

For healthcare handwashing, colder water appears just as effective as warm water, while also lowering resource use and Legionella risk.

Groups such as the ACR object to a CMS ‘frailty-exemption’ rule intended to make clinicians try to judge patients’ ability to work, noting among their objections a lack of adequate tools for this task.

New research is exploring whether sexual experience may shape brain circuits linked to reward, learning, and mood — but the human evidence remains early.

Acquired somatic variants may drive over 20% of systemic autoinflammatory disease diagnoses, with VEXAS syndrome and cryopyrin-associated periodic syndromes representing the majority of cases.

A sonographer shortage confronts expectant women in Ontario with long commutes for routine ultrasounds.

A Spanish sexologist says the key to better STI detection may be simpler than it seems: create a safe, nonjudgmental space and ask directly.

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At-Home Lecanemab: What Does It Mean for Alzheimer’s Care?

At-home subcutaneous lecanemab may ease the burden of frequent infusions, but clinicians still face key questions about patient selection, training, ARIA monitoring, adherence, and access.

Paternal Valproate Use Not Tied to NDDs in Offspring

Paternal exposure to valproate during spermatogenesis is not tied to a risk for neurodevelopmental disorders or congenital malformations in offspring, research shows.

Early Oseltamivir Tied to Lower Hospitalization Risk in Flu

Among adult veterans, oseltamivir treatment initiated within 6 hours of influenza diagnosis is associated with a reduced risk for hospitalization.

AI Outperforms Gene Sequencing for Lung Nodule Triage

Interpret findings with caution, but AI-based radiomics may help curb unnecessary procedures.

Discharge Support Remains Weak Spot in CQC Patient Survey

The CQC's 2025 survey of 58,000 patients found rising satisfaction overall, but discharge planning remains an area of difficulty.

Are Universal Digital Mental Health Interventions Effective?

In children without diagnosed mental health conditions, digital interventions are associated with small psychological improvements.

Canadian Bill Intended to Close Gaps in Women’s Healthcare

The comprehensive bill takes a multipronged approach to improving women’s health within a framework intended to keep future governments accountable.

West Nile Virus Infection Causes One Death in the Netherlands

A person has died in a Dutch hospital after ⁠contracting the West Nile virus in the Netherlands, the country's public ⁠health institution RIVM said on...

Statins Tied to Fewer Respiratory Infections in Older Adults

Among older adults unvaccinated against influenza, starting statins is associated with a lower risk for hospitalisation with pneumonia or other acute respiratory infections.

GCA Patients Often Need Long-Term Glucocorticoids

Despite rapid diagnosis and guideline-based tapering, a substantial proportion of patients with giant cell arteritis remain dependent on glucocorticoid therapy for years.

Artificial Intelligence Boosts Automated Biolabs

AI and machine learning are kicking synthetic biology up to new levels of innovation. Researchers see huge potential for novel drugs and other chemicals; some also see risks.

Can Conversational AI Platforms Free Up Physicians’ Time?

Conversational agents are taking on scheduling, intake, and follow-ups, whereas clinics assess whether automation can ease administrative demands on physicians.

Hospital Medicine: Good Onboarding of Hospitalists Pays Off

In years past, new hospitalists got a brief orientation and went to work. A more comprehensive approach — onboarding — is now the norm. It pays off in ways other than the bottom line.

Branded Bevacizumab: Retina Breakthrough or Bankbuster?

Bevacizumab is a cornerstone retina drug that has been used off-label for decades. Where the FDA-cleared branded version fits in may be a matter of cost and acceptance.

Worker Violence, Staff Shortages Spark Hospital Strikes

Healthcare workers are facing more violence and staff shortages, fueling hospital strikes as workers push for safer workplaces and enough staff to care for patients.

Retinal Thinning Predicts Cognitive Decline in MS

Thinning of specific retinal layers predicts cognitive worsening in patients with multiple sclerosis, even without disease relapses — suggesting the eye may reveal hidden neurodegeneration.

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