Studies have shown that neoadjuvant nivolumab may provide long-term benefits for people with non-small cell lung cancer.

Published Date: 17 Feb 2023

BACKGROUND: NSCLC is the most common and important cause of cancer worldwide. Assessment: The patient...

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Early clinical trial tests immune-boosting therapy before prostate cancer surgery

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The thymus hosts more 'cellular teachers' than we thought, study finds

A Czech scientist has contributed to understanding the function of the thymus—the training center of the immune system. T lymphocytes, key defensive cells, learn in the thymus not to mistake the body's own tissues for foreign ...

Todays Updates

Clinical trial sees dramatic results using radiation to treat breast cancer

Almost immediately after Theresa Greco was diagnosed with breast cancer in March, doctors asked her whether she wanted to participate in a clinical trial. The trial would do high-powered radiation targeted at her tumor prior ...

Dual-action mRNA vaccine takes aim at aggressive skin cancer

Yale researchers have developed a new vaccine that does double duty against a rare and aggressive skin cancer by targeting the protein essential to tumor cell growth and by adding a key signal to boost the immune system response. ...

Indoor hydroponic gardening can improve mental health and quality of life for cancer patients

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For incarcerated people, study shows gaps exist in quality of cancer care

In the United States, the incarcerated population is aging. About 15% of incarcerated adults, or approximately 175,000 people, are now 55 years or older.

Todays Updates

Clinical trial sees dramatic results using radiation to treat breast cancer

Almost immediately after Theresa Greco was diagnosed with breast cancer in March, doctors asked her whether she wanted to participate in a clinical trial. The trial would do high-powered radiation targeted at her tumor prior ...

Dual-action mRNA vaccine takes aim at aggressive skin cancer

Yale researchers have developed a new vaccine that does double duty against a rare and aggressive skin cancer by targeting the protein essential to tumor cell growth and by adding a key signal to boost the immune system response. ...

Indoor hydroponic gardening can improve mental health and quality of life for cancer patients

Indoor hydroponic gardening—a method of growing plants using nutrient-rich water instead of soil—could help cancer patients develop better mental health, eat a healthier diet and enjoy a better overall quality of life.

For incarcerated people, study shows gaps exist in quality of cancer care

In the United States, the incarcerated population is aging. About 15% of incarcerated adults, or approximately 175,000 people, are now 55 years or older.

Latest News

A small group of women with advanced breast cancer received a vaccine via a clinical trial more than 20 years ago. Today, they're all still alive. Scientists say that kind of long-term survival is almost unheard of for patients ...

A study led by UCLA Health Jonsson Comprehensive Cancer Center investigators reveals how melanoma, the deadliest form of skin cancer, evolves to resist immunotherapy and identifies a potential strategy to prevent or reverse ...

Leiden researchers have found clues to why a rare pregnancy disorder is mild in some babies but life-threatening in others. Their discovery opens the door to a test that could identify severe cases during pregnancy. Fortunately, ...

A small, early clinical trial led by the Icahn School of Medicine at Mount Sinai and collaborators has shown that directly injecting an immune-activating compound into prostate tumors before surgery appears safe and may help ...

Scientists have demonstrated for the first time how Staphylococcus aureus—a leading cause of skin infections—reshapes the immune system's inflammatory responses in children with a rare skin condition.

A Czech scientist has contributed to understanding the function of the thymus—the training center of the immune system. T lymphocytes, key defensive cells, learn in the thymus not to mistake the body's own tissues for foreign ...

News All Time

Potential cancer outcome differences among psoriasis biologics found

Copenhagen University Hospital–Herlev and Gentofte led a nationwide registry study that the authors claim shows a "pattern suggesting" a lower five-year risk of any first cancer (excluding non-melanoma skin cancer) with ...

Influenza A-infected volunteers display different patterns of expelling viruses into environment

Late in the Middle Ages, Italian stargazers gave a name to the annual contagion that rolled around each year like clockwork. It was a name that stuck, and to this day is known as influenza.

BiTE-based immunotherapy strategy could point the way to a breakthrough for ovarian cancer patients

Results of a study led by researchers at Roswell Park Comprehensive Cancer Center show that combining two types of immunotherapy—engineered T cells that secrete bispecific T cell engagers (BiTEs) and an immune checkpoint ...

Improving immunotherapy responses to fight cancer with dual therapies

Promising study in dual inhibition of PD1 and macrophage migration inhibitory factor

Breastfeeding linked to lasting immune protection against breast cancer

A team of researchers led by Peter Mac's Professor Sherene Loi has uncovered how having children and breastfeeding reduces a woman's long-term risk of breast cancer.

Promising new drug combination for melanoma patients resistant to treatment

Melanoma is the most common form of skin cancer, but for patients with advanced melanoma who no longer respond to standard immunotherapy, treatment options are painfully limited. Vanderbilt researchers led by Professor Emerita ...

Localized IL-12 delivery reshapes CAR-T safety in solid tumors

An international collaboration of researchers, including Imperial College London and UCLA, has developed a collagen-binding interleukin 12 strategy that lets CAR-T cells treat prostate cancer in mice while curbing previously ...

Mitochondria and lysosomes reprogram immune cells that dampen inflammation

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children's Research Hospital scientists recently uncovered how mitochondria, ...

Immune-hot brain tumor subtype that defies survival expectations discovered

A research team has discovered a previously overlooked subtype of brain tumor termed IME IDH-mutant astrocytoma. Contrary to typical medical expectations, this subtype exhibits strong immune activity, classified as "immune‑hot," ...

Potential antibody therapy restricts the growth of aggressive and treatment-resistant breast cancers

A new potential antibody therapy strategy which restricts the growth of treatment-resistant breast cancers has been developed by scientists.

Decades-old asthma theory challenged: Newly discovered molecules may be real drivers of disease

For decades, scientists have thought they understood the biochemical machinery that causes asthma—inflammation in the lungs that constricts airways and makes it hard to breathe.

Researchers develop innovative vascularized tumor model to advance cancer immunotherapy

A research team led by the Faculty of Dentistry at The University of Hong Kong (HKU) has developed a novel vascularized tumor model using a non-surgical injectable hydrogel system. This innovative approach provides a powerful ...

New targeted therapy shows promise for patients with advanced bladder cancer

FX-909, a first-in-class investigational oral small molecule inhibitor of peroxisome proliferator-activated receptor gamma (PPARG), showed early signs of clinical benefit in patients with advanced urothelial carcinoma, according ...

Elironrasib may overcome resistance to prior KRAS G12C inhibition in non-small cell lung cancer

Elironrasib led to meaningful and durable responses in patients with metastatic KRAS G12C-mutated non-small cell lung cancer (NSCLC), including after prior treatment with KRAS G12C inhibitors and in the presence of features ...

Investigational antibody-drug conjugate shows clinical benefit against previously treated small cell lung cancer

Zocilurtatug pelitecan (zoci), also known as ZL-1310, an investigational antibody-drug conjugate (ADC) that targets the protein DLL3, demonstrated both safety and capacity to induce anticancer responses in patients with extensive-stage ...

Scientists develop one-product-fits-all immunotherapy for breast cancer

Triple-negative breast cancer is one of the most aggressive cancers. The name tells the story: It lacks the three main targets that make other types of breast cancers more treatable with powerful therapies.

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