Studies have shown that neoadjuvant nivolumab may provide long-term benefits for people with non-small cell lung cancer.

Published Date: 17 Feb 2023

BACKGROUND: NSCLC is the most common and important cause of cancer worldwide. Assessment: The patient...

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Living Near a Dry Cleaner Tied to Higher PD Risk

Living within 500 ft of a dry cleaner is linked to a 14% increased PD risk for vs living 4-5 miles away, with the strongest associations seen in certain US regions and in the gait-instability subtype.

Defining COPD Phenotypes With Advanced Imaging

Visual characteristics of lung disease are helping pulmonologists establish care plans and interventions.

Triple Therapy Reduces Antibiotic Use in Pediatric CF

A triple-combination therapy targeting the underlying defect in cystic fibrosis was associated with a dramatic reduction in antibiotic exposure among children and adolescents.

NHS Rehab Cuts Leaving Patients With ‘Avoidable Disability’

Recruitment freezes and lost rehab space are harming patient care, a CSP survey of 548 NHS physiotherapists finds.

ACARD Score Predicts Mortality in Status Epilepticus

A newly developed prognostic tool outperforms existing scoring systems in predicting short-term mortality risk following status epilepticus.

THC Safe, Effective for PTSD-Related Nightmares

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Freeman’s Lobotomy to Deep Brain Stimulation: What Changed?

The history of lobotomy shows the risks for limited evidence and oversight, while modern approaches emphasize targeted treatment, informed consent, and rigorous evaluation.

Wide Variation Seen in Lung Screening False-Positive Rates

US radiologists vary substantially in their reading of low-dose CT lung cancer screens, highlighting a need for measures to help standardize interpretation.

AVD Chemo Regimen Shows Promise in Older Patients With HL

Researchers compare first-line chemotherapy regimens in older patients with classical Hodgkin lymphoma to assess whether AVD is associated with better outcomes in routine care.

Do High-Risk Features of Prostate Cancer Boost HT Benefit?

Researchers analyze individual patient data from five randomized phase 3 trials comparing PORT alone vs PORT plus hormone therapy in patients with recurrent prostate cancer.

How Low Does PSA Need to Go in Metastatic Prostate Cancer?

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Tissue-Free ctDNA Strongly Prognostic of Recurrence in TNBC

Tissue-free ctDNA may be comparable to tumor-informed assays in detecting molecular residual disease.

Todays Updates

Freeman’s Lobotomy to Deep Brain Stimulation: What Changed?

The history of lobotomy shows the risks for limited evidence and oversight, while modern approaches emphasize targeted treatment, informed consent, and rigorous evaluation.

Wide Variation Seen in Lung Screening False-Positive Rates

US radiologists vary substantially in their reading of low-dose CT lung cancer screens, highlighting a need for measures to help standardize interpretation.

AVD Chemo Regimen Shows Promise in Older Patients With HL

Researchers compare first-line chemotherapy regimens in older patients with classical Hodgkin lymphoma to assess whether AVD is associated with better outcomes in routine care.

Do High-Risk Features of Prostate Cancer Boost HT Benefit?

Researchers analyze individual patient data from five randomized phase 3 trials comparing PORT alone vs PORT plus hormone therapy in patients with recurrent prostate cancer.

How Low Does PSA Need to Go in Metastatic Prostate Cancer?

A new real-world analysis helps clarify the most informative prognostic PSA benchmark in men with metastatic castration-sensitive prostate cancer.

Tissue-Free ctDNA Strongly Prognostic of Recurrence in TNBC

Tissue-free ctDNA may be comparable to tumor-informed assays in detecting molecular residual disease.

Latest News

Living within 500 ft of a dry cleaner is linked to a 14% increased PD risk for vs living 4-5 miles away, with the strongest associations seen in certain US regions and in the gait-instability subtype.

Visual characteristics of lung disease are helping pulmonologists establish care plans and interventions.

A triple-combination therapy targeting the underlying defect in cystic fibrosis was associated with a dramatic reduction in antibiotic exposure among children and adolescents.

Recruitment freezes and lost rehab space are harming patient care, a CSP survey of 548 NHS physiotherapists finds.

A newly developed prognostic tool outperforms existing scoring systems in predicting short-term mortality risk following status epilepticus.

Dronabinol, a medication containing THC, is linked to fewer nightmares at lower intensity compared to placebo in patients with post-traumatic stress disorder, new data show.

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Vancomycin Prophylaxis Tied to Lower C difficile Recurrence

In children and young adults with cancer, oral vancomycin prophylaxis during broad-spectrum antibiotic therapy is associated with a lower risk for recurrent Clostridioides difficile infection.

Spousal Dementia Tied to Higher Dementia Risk

Spouses of individuals with dementia have a significantly higher risk of developing dementia, new research shows.

Romanian Healthcare Workers Strike Over Wage Bill Needed to Secure EU Funds

Thousands of Romanian doctors, nurses and other health workers went on an indefinite strike ⁠for the first time in a decade on Tuesday, protesting job freezes and a public...

Infections Tied to Increased Risk for Brain Disorders

Hospitalization due to an acute infection, especially infectious encephalitides, is linked to increased risk for psychiatric and neurologic disorders, a new study shows.

The Restorative Power of ‘Sacred Moments’ in Medicine

Deep human connection can be a potent antidote to burnout. Here’s how to cultivate meaning in an increasingly rushed healthcare system.

US FDA Approves Outlook Therapeutics' Eye Disease Drug

Outlook Therapeutics said on Friday the U.S. Food and Drug Administration has approved its drug for ⁠a type of eye disease that can cause vision loss.

Nasal IgA Protects Against H1N1, SARS-CoV-2 Infections

High baseline nasal IgA, not serum IgG, was linked to lower risk for influenza A H1N1 infection in a real-world study.

Punchlines and Pathology: The Secrets of Laughter Explained

A new review of data from patients with epilepsy describes two distinct neural networks, offering clinicians and patients a way to better understand laughter as a neurologic malfunction.

Gene Therapy Delivers Sustained Retinal Protection

People with age-related macular degeneration maintain vision and cut their need for supplemental injections by 90% 5 years after receiving gene therapy.

Online Harassment: Should Doctors Stay on Social Media?

Online harassment increasingly targets physicians who share evidence-based information, prompting calls for stronger institutional support and safer public engagement.

Post-Pandemic Burnout: NP, PAs Face Different Challenges

The struggles advanced practice practitioners face are different than those that physicians deal with. But the threats are the same.

Ethical Conflict Common in Maternity Care

Providers who work as midwives, in both inpatient and outpatient settings, in southern US states, or who do not have kids may face the most ethical conflicts over drug testing and child welfare reporting.

Sugammadex Reduces Post-Op Lung Complications

Reversal of neuromuscular block with sugammadex reduces the risk for post-op pulmonary complications or death compared with neostigmine in older adults undergoing major abdominal or thoracic surgery.

Faricimab May Aid Hard-to-Treat Macular Degeneration Cases

Faricimab may stabilize vision, reduce retinal fluid and thickness, and cut treatment burden in difficult-to-treat cases of wet age-related macular degeneration.

Delays Harmless for Most Macular Degeneration Patients

Waiting for prior authorization of drugs affects a small portion of patients with age-related macular degeneration, resulting in vision loss.

Sri Lanka Uses Air Force Drones to Tackle Spreading Dengue Outbreak

Sri Lanka's public health services and hospitals are battling the worst outbreak of mosquito-borne dengue in nearly a decade, and turning to the island nation's armed...

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