ROC-SpA: IL-17i Not Superior to Cycling TNFi Post-Failure in AxSpA Victoria Johnson

Published Date: 21 Nov 2025

Switching to an IL-17 inhibitor after TNF inhibitor failure showed no superior benefits for axial spondyloarthritis.

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Lupus contributes substantially to premature mortality in young women, with over 304,000 years of potential life lost in women aged 15-44 years from 2000 to 2015.

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American patients report more symptoms and mostly don't agree with doctors on how they've fared

Medicare Coverage Appears Spotty for Newer Rheumatoid Arthritis Meds

Advantage plans do a better job than standalone Part D policies, albeit with important gaps

ICE Chief Hospitalized; Metastatic Colon Cancer at Age 26; TENS for Fibromyalgia

Health news and commentary gathered by MedPage Today staff

Dyspnea in Woman With RA Reveals a Diaphragmatic Lipoma

MRI can help differentiate these benign soft-tissue masses from more aggressive liposarcomas

What Caused This Patient's Recurring Eye and Ear Inflammation?

Prompt diagnosis of this rare progressive autoimmune disease may help preserve hearing, eyesight

What Caused Left-Sided Hearing Loss in This 65-Year-Old Man?

Numerous diagnostic procedures revealed tophaceous gout affecting the middle ear

EULAR: Docs Should Push Hard on Physical Activity for Arthritis Patients

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Drug Targeting TLRs in Cutaneous Lupus Looks Good in Mid-Stage Studies

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Upadacitinib After TNF Inhibitor Failure Improves RA Control

In patients with active RA, switching to upadacitinib after failure of a single TNF inhibitor is more effective in reducing disease activity at 12 weeks than using a second TNF inhibitor adalimumab.

Early Anti-TNF to Prevent Difficult-to-Treat RA Gains Steam

The availability of TNF inhibitor biosimilars and the cost of treating ‘difficult-to-treat’ RA are making first-line TNF inhibition in early RA more attractive in the UK.

FDA Grants Breakthrough Therapy Designation to Ianalumab, First Potential Sjögren’s Targeted Therapy Victoria Johnson

Novartis plans to submit regulatory applications for ianalumab in early 2026.

FDA Updates Label for Reduced Osteoarthritis Risk With BEAR Implant Over ACL Reconstruction Victoria Johnson

FDA approves a label update for the BEAR implant, which was previously approved in 2020.

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argenx's efgartigimod-alfa therapy was approved for seropositive generalized myasthenia gravis in 2021.

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