Isolated nail psoriasis may be a sign of psoriatic arthritis

Published Date: 02 Mar 2023

In a review of 87 patients, the authors recorded the clinical and histological characteristics of patients with nail psoriasis.

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Pentoxifylline Analog Shows Promise for Rare Skin Disease

An oral deuterated pentoxifylline analog demonstrates a favorable safety and improves clinical outcomes in adults with necrobiosis lipoidica, a phase 2 study shows.

Neurologic Side Effects Rare but Often Severe with ICIs

A retrospective study highlights the potential for encephalitis and other serious neurologic side effects over the course of immune checkpoint inhibitor therapy.

AI Skin Cancer Apps: Do They Work?

A clinical trial designed to test an AI-based skin cancer detection app has some surprising results.

No Survival Gain With Adjuvant Therapy in Stage III Melanoma

Adjuvant therapy improves neither melanoma-specific nor overall survival in patients with stage III disease, conclude Swedish researchers in an updated population-based study.

Clobetasol Cuts Vulvar Cancer Risk in Lichen Sclerosus

Clobetasol reduces vulvar malignancy risk at 2 years after diagnosis; topical calcineurin inhibitors do not increase malignancy risk.

Tanning Beds Tied to Higher Melanoma Risk

A study finds 13.4% of people aged 15-75 years have used tanning booths; experts urge stricter regulation, targeted public education, and updated surveillance of users.

Todays Updates

PSA Screening Overdiagnosis Rises Sharply With Age

About one third of cancers detected by PSA screening at age 70, and more than half at age 80, are unlikely to become clinically meaningful within 15 years.

Can Exercise Extend Survival After Breast Cancer?

A ‘target trial’ emulation study suggests that regular exercise can help breast cancer survivors live longer.

Liquid Biopsies Cut EBV Burkitt Lymphoma Time to Diagnosis

Broader implementation would require substantial investment, but long-term dividends of liquid biopsy analysis in the region could affect diagnosis and care of much more than just this cancer.

High Fruit, Veggie Diet Tied to Early-Onset Lung Cancer?

Counterintuitive findings hint that diets rich in fruit, vegetables, and whole grains may increase the risk of lung cancer in young nonsmokers, but experts are skeptical.

Photopenia on [18F]FDG PET/CT Predicts Benign Renal Lesions

Photopenia in high CT density renal lesions on [18F]FDG PET/CT scans shows a high negative predictive value for excluding malignancy.

Can Alternating Venetoclax Regimens Improve AML Outcomes?

A phase 2 study investigates the combination of cladribine plus low-dose cytarabine and venetoclax alternating with azacitidine plus venetoclax for newly diagnosed acute myeloid leukemia.

Vepdegestrant Earns FDA Nod for ESR1-Mutated Breast Cancer

Approval was based on findings from the phase 3 VERITAC-2 trial showing significantly improved PFS for patients with ESR1-mutated disease.

Todays Updates

PSA Screening Overdiagnosis Rises Sharply With Age

About one third of cancers detected by PSA screening at age 70, and more than half at age 80, are unlikely to become clinically meaningful within 15 years.

Can Exercise Extend Survival After Breast Cancer?

A ‘target trial’ emulation study suggests that regular exercise can help breast cancer survivors live longer.

Liquid Biopsies Cut EBV Burkitt Lymphoma Time to Diagnosis

Broader implementation would require substantial investment, but long-term dividends of liquid biopsy analysis in the region could affect diagnosis and care of much more than just this cancer.

High Fruit, Veggie Diet Tied to Early-Onset Lung Cancer?

Counterintuitive findings hint that diets rich in fruit, vegetables, and whole grains may increase the risk of lung cancer in young nonsmokers, but experts are skeptical.

Photopenia on [18F]FDG PET/CT Predicts Benign Renal Lesions

Photopenia in high CT density renal lesions on [18F]FDG PET/CT scans shows a high negative predictive value for excluding malignancy.

Can Alternating Venetoclax Regimens Improve AML Outcomes?

A phase 2 study investigates the combination of cladribine plus low-dose cytarabine and venetoclax alternating with azacitidine plus venetoclax for newly diagnosed acute myeloid leukemia.

Vepdegestrant Earns FDA Nod for ESR1-Mutated Breast Cancer

Approval was based on findings from the phase 3 VERITAC-2 trial showing significantly improved PFS for patients with ESR1-mutated disease.

Latest News

An oral deuterated pentoxifylline analog demonstrates a favorable safety and improves clinical outcomes in adults with necrobiosis lipoidica, a phase 2 study shows.

A retrospective study highlights the potential for encephalitis and other serious neurologic side effects over the course of immune checkpoint inhibitor therapy.

A clinical trial designed to test an AI-based skin cancer detection app has some surprising results.

Adjuvant therapy improves neither melanoma-specific nor overall survival in patients with stage III disease, conclude Swedish researchers in an updated population-based study.

Clobetasol reduces vulvar malignancy risk at 2 years after diagnosis; topical calcineurin inhibitors do not increase malignancy risk.

A study finds 13.4% of people aged 15-75 years have used tanning booths; experts urge stricter regulation, targeted public education, and updated surveillance of users.

News All Time

Regeneron Wins FDA Approval for First Gene Therapy for Genetic Hearing Loss

The U.S. Food and Drug Administration has approved Regeneron's gene therapy for a rare genetic form of ⁠deafness, the company said on Thursday.

AI Holds Promise in Dermatology, Concerns Remain

The potential benefits and pitfalls of this rapidly evolving technology for dermatologists are debated at AAD 2026.

Spanish Medical Residents Prioritize Work-Life Balance

Many residents say fewer on-call shifts, predictable hours and less urgent care drive specialty choice, pushing interest toward endocrinology, clinical pharmacology and occupational medicine.

Low-Dose Oral Minoxidil: Hair Growth May Peak After 6 Months

Low dose oral minoxidil yields measurable increases in frontal hair density by 3-6 months, with no further significant gains up to 36 months, a retrospective review finds.

Can Healthy Lifestyle Improve Quality of Life in Psoriasis?

High levels of physical activity, adequate sleep, and a healthy BMI are linked to lower odds of quality-of-life impairments in patients with psoriasis.

Infrequent Primary Care Consulters Face Higher Cancer Risk

Patients who visit the doctor less often before their urgent suspected cancer referrals are more likely to receive a diagnosis of cancer than those who consult more frequently.

Cosmo Pharma's Male Hair Loss Treatment Shows Sustained Hair Growth in Year‑long Study

Cosmo Pharmaceuticals said on Wednesday its experimental hair loss treatment showed sustained hair growth ⁠and long-term safety in men with common pattern baldness after a...

Lung Test May Predict Transition From Early to Definite SSc

A lower initial lung diffusion capacity for carbon monoxide is associated with a higher rate of progression from very early diagnosis to definite systemic sclerosis.

IDEAYA and Servier's Eye Cancer Drug Meets Trial Goal, Paving Way for FDA Application

IDEAYA Biosciences and French pharma company Servier said on Monday their combination drug for a type of ⁠eye cancer met the main goal of a mid-to-late-stage trial, sending...

Oral JAK1 Inhibitor Povorcitinib Shows Promise in HS

Abscesses and nodules improve significantly at 12 and 54 weeks.

Predictors of Rare Form of Crohn’s Disease Identified

Perianal disease involvement and a history of an ostomy are associated with increased odds of developing metastatic cutaneous Crohn’s disease.

Cosmetic Eyelash Extensions Linked to Dry Eye Symptoms

Eye symptoms affect most recipients of lash lifts and extensions, with an independent association with dry eye in an observational study.

FDA Approves Radiesse Filler for Decolletage Wrinkles

An agency advisory committee in 2025 recommended more study of fillers in that body area to address potential safety concerns.

Insmed Discontinues Development Of Skin Condition Drug After Mid-stage Study Miss

Insmed said on Tuesday it would discontinue the development ⁠of its treatment for a chronic, inflammatory skin condition, after ⁠the drug failed a mid-stage...

Dermocosmetics: Are Therapeutic Cosmetics Real?

From acne to rosacea, growing evidence shows targeted dermocosmetics can serve as monotherapy for mild disease or as adjunctive care, improving outcomes and treatment tolerability.

Cutaneous Appendageal Tumors: Worse Outcomes in Black People

Black patients wait weeks longer for therapy than White patients following diagnosis with rare skin cancer, and on average, deaths occur earlier.

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