IV Dexamethasone Ranks Best Against Post-Block Rebound Pain

Published Date: 05 Jun 2026

A new analysis ranks intravenous administration of dexamethasone as the most effective approach to prevent rebound pain after peripheral nerve block, whereas preemptive opioids offer little relief.

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The Hidden Cost of Racial Bias in Medicine

From delayed diagnoses to unequal pain treatment, racial bias in medicine can shape care in ways clinicians may not even notice.

Should Epinephrine Be Removed From Shockable Arrests?

Drs Robert Glatter and Peter Antevy argue that epinephrine may worsen outcomes in shockable cardiac arrest and explain why early defibrillation, DSED, and high-performance CPR should take priority.

Does Anesthesia Choice Affect Postpartum Depression Risk?

Mothers who receive neuraxial anesthesia during cesarean delivery have a lower risk for postpartum depression within 1 year than those who receive general anesthesia, a new study shows.

Conjugated Pneumococcal Vaccines Have Transformed Pediatrics

Rates of acute otitis media, acute sinusitis, lobar pneumonia, pneumococcal meningitis, and bacteremia decreased substantially after the introduction of the first pneumococcal vaccine in 2000.

Jun 12 2026 This Week in Cardiology

Listener feedback, transcatheter tricuspid valve replacement, a new metabolic disease called CKM, the ARISE-FLUIDS Trial, the BIHCA trial, and temporal trends in ICD therapies are the topics John Mandrola, MD, discusses in this week’s podcast.

Psoriasis Tied to Chronic Intense Pain, Multiple Pain Sites

A population-based study reports that psoriasis is associated with chronic pain at multiple sites and with high intensity even after ruling out known diagnoses of psoriatic arthritis.

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HIV Care Coordination Program May Reduce Deaths in NYC

New York City’s revised Care Coordination Program may help reduce risks for all-cause and HIV-related deaths among people with HIV infection, including those at the highest risk for poor outcomes.

Teplizumab Approved for Pediatric Stage 3 Type 1 Diabetes

The drug was previously approved for stage 2 T1D.

One in Four Teen Girls and Young Women at Risk for PMOS

Findings suggest young females should be assessed and, if at risk, monitored.

Palopegteriparatide Benefits Sustained Beyond 3 Years

Final results from the PaTHway trial show the long-acting parathyroid hormone therapy enabled patients with hypoparathyroidism to achieve independence from high-dose calcium and vitamin D supplements.

Testosterone Prescribing Often Ignores Guidelines

Only 12% of patients prescribed testosterone underwent appropriate diagnostic testing, and overprescribing was common in a single-center US study.

Encaleret Shows Rapid Response in ADH1

The oral modulator of the calcium-sensing receptor targets the causes of ADH1, significantly improving serum and urine calcium levels.

Off-Label Rxs: Thinking Out of the Box for Skin Diseases

Off-label alternatives for FDA-approved therapies can be as effective, cheaper, and in some cases safer despite never having been submitted for regulatory approval.

Todays Updates

HIV Care Coordination Program May Reduce Deaths in NYC

New York City’s revised Care Coordination Program may help reduce risks for all-cause and HIV-related deaths among people with HIV infection, including those at the highest risk for poor outcomes.

Teplizumab Approved for Pediatric Stage 3 Type 1 Diabetes

The drug was previously approved for stage 2 T1D.

One in Four Teen Girls and Young Women at Risk for PMOS

Findings suggest young females should be assessed and, if at risk, monitored.

Palopegteriparatide Benefits Sustained Beyond 3 Years

Final results from the PaTHway trial show the long-acting parathyroid hormone therapy enabled patients with hypoparathyroidism to achieve independence from high-dose calcium and vitamin D supplements.

Testosterone Prescribing Often Ignores Guidelines

Only 12% of patients prescribed testosterone underwent appropriate diagnostic testing, and overprescribing was common in a single-center US study.

Encaleret Shows Rapid Response in ADH1

The oral modulator of the calcium-sensing receptor targets the causes of ADH1, significantly improving serum and urine calcium levels.

Off-Label Rxs: Thinking Out of the Box for Skin Diseases

Off-label alternatives for FDA-approved therapies can be as effective, cheaper, and in some cases safer despite never having been submitted for regulatory approval.

Latest News

From delayed diagnoses to unequal pain treatment, racial bias in medicine can shape care in ways clinicians may not even notice.

Drs Robert Glatter and Peter Antevy argue that epinephrine may worsen outcomes in shockable cardiac arrest and explain why early defibrillation, DSED, and high-performance CPR should take priority.

Mothers who receive neuraxial anesthesia during cesarean delivery have a lower risk for postpartum depression within 1 year than those who receive general anesthesia, a new study shows.

Rates of acute otitis media, acute sinusitis, lobar pneumonia, pneumococcal meningitis, and bacteremia decreased substantially after the introduction of the first pneumococcal vaccine in 2000.

Listener feedback, transcatheter tricuspid valve replacement, a new metabolic disease called CKM, the ARISE-FLUIDS Trial, the BIHCA trial, and temporal trends in ICD therapies are the topics John Mandrola, MD, discusses in this week’s podcast.

A population-based study reports that psoriasis is associated with chronic pain at multiple sites and with high intensity even after ruling out known diagnoses of psoriatic arthritis.

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Which Patients With Early HCC Should Undergo Resection?

Analysis of 2869 patients suggest resection may improve overall and disease-free survival vs RFA/TACE in selected early multinodular HCC.

Dual Plane Block May Cut Opioid Use After Bypass Surgery

Adding a serratus anterior plane block to a parasternal intercostal plane block may reduce opioid use and attenuate pain at drain sites after coronary artery bypass grafting.

When War Disrupts the Medicine Cabinet

The Gulf conflict is disrupting NHS medicine supplies — and for patients who cannot miss a dose, the consequences can be severe.

AHS 2026: Anticipating Key Advances in Migraine Treatment

Dr Nan Cheng previews migraine presentations on PACAP, suzetrigine, GLP 1 receptor agonists, and the glymphatic system’s role in migraine pain.

Conference MDAngle: AHS 2026 Migraine Treatment

Insights from AHS 2026, including anticipated presentations, key takeaways, and how new research in migraine treatment will affect patient care.

Canada: Physicians & Relationships Report 2026

Survey respondents open up about how work affects their relationships and how being a physician affects the search for an appropriate partner.

Chronic Pain: How to Wean Opioids From Arthritis Patients

Shared decision-making and good communication are key to helping patients with chronic pain reduce or stop opioids.

HEARTS 2.0: PAHO's 38-Step Pathway for Cardio-Renal Care

Backed by 26 ministries and GRADE evidence, PAHO's new clinical pathway could accelerate access to SGLT2 inhibitors and statins to curb cardiorenal complications.

Early Palliative Integration for Heart Failure

Heart failure’s unpredictable trajectory often delays palliative referral; early integration and proactive follow-up can identify worsening symptoms before a full decompensation.

Trust Is Becoming the Most Important Medicine We Have

John Whyte, MD, MPH, chief executive officer of the American Medical Association, shares how physicians can best respond to the “crisis in trust” with patients.

UK Physicians & Relationships Report 2026

Work pressures are straining doctors’ relationships, with many reporting impacts on time, intimacy, and connection — particularly among younger clinicians.

ECG Challenge: Chest Tightness During Sleep

A 70-year-old man with an ICD is awoken by sudden chest tightness and is rushed to the emergency department. What does the ECG reveal?

Congo's Ebola Responders Decry Lack Of Medicine, Masks, Motorbikes

First responders fighting Democratic Republic of Congo's 17th Ebola outbreak say even basic supplies are scarce - from pain medicine, to motorbikes for contact tracing and...

Polypsychopharmacy on the Rise in Primary Care

A recent study shows that the concomitant use of two or more classes of psychotropic medication has risen among adult patients in Dutch primary care over a 10-year period.

A Post-Op Death, a Physician’s Personal Grief

Her brother’s death from a post-op pulmonary embolism left this cardiologist not only grieving but feeling guilty about the what-ifs.

10 Bucket List Vacation Ideas for Doctors

Discover the awe-inspiring destinations that top physicians' ultimate travel wish lists.

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