Mefitel film for radiation dermatitis: it works, why not?

Published Date: 13 Mar 2023

According to the results of a phase 3 trial, the use of silicone film before radiotherapy can reduce the incidence of radiodermatitis, so why not use it?

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In a northeastern Congolese province, rumours rippled through villages claiming a mysterious illness had caused men's genitals to atrophy. The panic turned deadly within days.

Evidence indicates that early interruptions during consultations can lead to missed symptoms and incomplete histories that affect clinical decision-making.

Compared to routine care, stem cell-enriched autologous lipotransfer produces significantly greater improvement in orofacial fibrosis in patients with systemic sclerosis.

Global malaria cases are increasing despite vaccine progress, with funding gaps and resistance limiting the prevention and treatment impact.

Higher-dose ivermectin combined with permethrin does not improve cure rates compared with standard dosing in adults with severe scabies, study shows.

The questionnaire considers postoperative management, patient health status, and tumor-specific features to compare risks and benefits of Mohs vs other treatments in older and end-of-life patients.

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No Survival Gain With Adjuvant Therapy in Stage III Melanoma

Adjuvant therapy improves neither melanoma-specific nor overall survival in patients with stage III disease, conclude Swedish researchers in an updated population-based study.

Clobetasol Cuts Vulvar Cancer Risk in Lichen Sclerosus

Clobetasol reduces vulvar malignancy risk at 2 years after diagnosis; topical calcineurin inhibitors do not increase malignancy risk.

Tanning Beds Tied to Higher Melanoma Risk

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Hydroxychloroquine Level Monitoring Can Boost Lupus Control

Weight-based dosing misses accounting for factors such as chronic kidney disease or chronic transaminitis, which could potentially accelerate toxicity risk or increase the risk for SLE flares.

Pediatric Plaque Psoriasis Treatment Set to Expand in Europe

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Oruka Says Experimental Annual Psoriasis Treatment Clears Skin in Mid-stage Study

Oruka Therapeutics said on Monday that interim results showed its experimental drug helped clear psoriasis within 16 weeks, ⁠meeting the main goal of a mid-stage study and...

EMA Says No to Drug for PD-L1-High Melanoma

Although the agency did not recommend an extension of Opdualag’s indications, it did say new data could be added to its product information.

US FDA Rejects AbbVie's Wrinkle Treatment Due to Manufacturing Concerns

AbbVie said on Thursday the U.S. Food and Drug ⁠Administration has declined to approve its experimental wrinkle treatment, trenibotE, citing issues ⁠in...

Skin-Picking and Hair-Pulling Disorders: Which Drugs Work?

Glutamatergic agents, including an over-the-counter therapy, are showing promise.

AI Tools Aid Lung Disease Detection in Autoimmune Diseases

AI-based deep learning models can detect interstitial lung disease from lung ultrasound images in patients with systemic sclerosis and idiopathic inflammatory myopathy.

Extended Antibiotic Use Common in Children With HS

Children with hidradenitis suppurativa often receive antibiotics for about a year before switching to other therapies, a study shows.

Laser Pretreatment Boosts Actinic Keratosis Clearance

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Ultrasonography and CT beat physical exam for nodal metastasis detection in patients with high-risk skin cancer but show poor sensitivity in immunosuppressed patients.

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The U.S. Food and Drug Administration has approved Regeneron's gene therapy for a rare genetic form of ⁠deafness, the company said on Thursday.

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