Episode 3: Targeted Therapy in Endometrial Cancer

Published Date: 27 Jul 2024

Drs Ursula A. Matulonis and Joyce F. Liu discuss new therapeutics for patients with endometrial cancer, including ADCs, immunotherapy, and drugs targeting replication stress.

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In breast cancer, molecular resistance can precede clinical progression, but should it prompt an immediate change in treatment?

Performing a punch biopsy doesn't have to be daunting. Learn the essential steps every PCP needs to confidently sample, suture, and care for biopsy sites.

Most thyroid nodules are benign, but risk stratification matters. Learn how ultrasound, TI-RADS, and postbiopsy tools guide smarter referral decisions.

Learn how to perform a tangential shave biopsy with confidence. This step-by-step guide walks PCPs through the essential technique for sampling skin lesions and tumors.

Before you freeze a skin lesion, ask yourself whether you really know what it is. Here are four signs you should biopsy instead of freeze.

BRCA testing now guides urgent treatment decisions as well as family risk assessment, and Spanish experts highlight its implications for PARP inhibitors, oncofertility, liquid biopsy, and exercise.

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Excess and Dysfunctional Fat as a Primary Driver of HFpEF

The role of excess and dysfunctional fat in the genesis of HFpEF is well recognized, likely representing a primary or major upstream contributing cause in the large majority of patients.

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S1 Episode 6: Choosing Therapies for ATTR-CM in 2026

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Melanoma Clues Every PCP Should Know

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S1 Episode 3: Incidental Fatty Liver on Imaging: What Should You Do Next?

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Pott’s Puffy Tumor in Teen Leads to Bilateral Blindness

A teen with Pott’s puffy tumor develops irreversible bilateral blindness after delayed diagnosis and intracranial complications, highlighting the importance of its early recognition.

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Preventive neurologists Richard Isaacson and Jennifer Buczyner discuss the role of anti-amyloid drugs in patients with Alzheimer’s or mild cognitive impairment.

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The latest evidence suggests multicancer early detection could expand screening beyond mammography and colonoscopy, yet key questions on outcomes and false positives remain.

A 5-Week-Old Male Presents With Blisters on His Right Leg

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Fever and Rash Reveal Japanese Spotted Fever in Woman

Recognizing fever, rash, and an eschar after tick exposure can support early diagnosis and timely antibiotic treatment, reducing the risk for severe complications.

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Drs Ursula A. Matulonis and Marisa R. Nucci discuss the future of AI and pathology and how genetics and genomics play a role in the diagnosis of endometrial cancer.

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