Postoperative metabolic control improves the outcome of hypophosphatemic rickets

Published Date: 17 Mar 2023

Orthopedic surgery plays an important role in the treatment of all deformities in children with rare types of hypophosphatemic rickets.

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Winter Sports and Lower Limb Motor Disability

People with lower limb motor disability need tailored equipment, training, and medical oversight to boost performance while preventing upper limb overload and skin problems.

Early Sports Specialization Affects Hip Development

New research suggests that kids who focus on one sport are more likely to experience physical problems later, hip injury in particular.

Ascendis Wins US Approval for Therapy for Children With Dwarfism

The U.S. Food and Drug Administration on Friday approved Ascendis Pharma's once-weekly therapy ⁠for children with a rare genetic disorder that causes dwarfism, the company...

Enzyme provides promising path to degenerative joint diseases cure

Degenerative joint diseases like osteoarthritis and intervertebral disk degeneration are conditions that affect millions of people worldwide, leading to pain and reduced mobility. These diseases remain incurable because current ...

New points to consider in treatment-resistant psoriatic arthritis

Some people with psoriatic arthritis (PsA) may have a disease that is difficult to manage (D2M) or does not respond to treatment. EULAR—The European Alliance of Associations for Rheumatology—has released new evidence-based ...

Study finds improvement in knee pain with exercise and physical therapy

People with a meniscal tear and osteoarthritis prescribed home exercises with or without physical therapy reported substantial improvements in knee pain, according to a new study led by Mass General Brigham researchers.

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Canadian Group Calls for Earlier Colorectal Cancer Screening

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Triplet Therapy Improves Posttransplant Outcomes in Myeloma

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Q&A: Nipple-Sparing Mastectomy After Breast Radiation

Although many surgeons avoid it, nipple-sparing mastectomy after radiation is a feasible alternative to skin-sparing mastectomy and may help preserve patients’ psychological well-being.

Todays Updates

Canadian Group Calls for Earlier Colorectal Cancer Screening

Modelling shows fewer cases and deaths with screening starting at age 45 years.

Triplet Therapy Improves Posttransplant Outcomes in Myeloma

A phase 3 trial examines whether carfilzomib-lenalidomide-dexamethasone maintenance therapy improves disease control compared with lenalidomide alone in patients with multiple myeloma.

Q&A: Nipple-Sparing Mastectomy After Breast Radiation

Although many surgeons avoid it, nipple-sparing mastectomy after radiation is a feasible alternative to skin-sparing mastectomy and may help preserve patients’ psychological well-being.

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People with lower limb motor disability need tailored equipment, training, and medical oversight to boost performance while preventing upper limb overload and skin problems.

New research suggests that kids who focus on one sport are more likely to experience physical problems later, hip injury in particular.

The U.S. Food and Drug Administration on Friday approved Ascendis Pharma's once-weekly therapy ⁠for children with a rare genetic disorder that causes dwarfism, the company...

Degenerative joint diseases like osteoarthritis and intervertebral disk degeneration are conditions that affect millions of people worldwide, leading to pain and reduced mobility. These diseases remain incurable because current ...

Some people with psoriatic arthritis (PsA) may have a disease that is difficult to manage (D2M) or does not respond to treatment. EULAR—The European Alliance of Associations for Rheumatology—has released new evidence-based ...

People with a meniscal tear and osteoarthritis prescribed home exercises with or without physical therapy reported substantial improvements in knee pain, according to a new study led by Mass General Brigham researchers.

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Joint pain or osteoarthritis? Exercise could be the first line of treatment

Stiff knees, aching hips and the slow grind of chronic joint pain are often accepted as an unavoidable part of getting older. But while osteoarthritis is the world's most common joint disease, experts say the way we treat ...

Study finds tailored exercise program feasible for adults over 80 with osteoarthritis

A new NDORMS study has found that a tailored exercise program for people aged 80 years and older with hip and/or knee osteoarthritis and other long term health conditions is both practical and acceptable, paving the way for ...

New treatment for psoriatic arthritis shows promising results in early trial

A new treatment for a debilitating inflammatory condition which affects joints and skin has shown promising early results in an international clinical trial of more than 200 patients worldwide.

Seven-year study reveals rheumatoid arthritis begins long before symptoms, opening door to prevention 

Scientists have discovered that rheumatoid arthritis (RA) doesn't start when the pain begins. It silently starts years earlier. RA is a debilitating autoimmune disease that causes painful joint inflammation and damage. The ...

Self-guided online program improves quality of life in rheumatoid arthritis, psoriatic arthritis and lupus

Patients with rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus frequently face anxiety and depression along with chronic physical symptoms. Reported rates of depression range from 15% to 24% and ...

Analysis isolates population aging as primary driver of musculoskeletal disorders

Novel research shows that in approximately one third of countries and territories worldwide, population aging was the largest contributor to the growing burden of musculoskeletal disorders from 1990 to 2021.

Tirzepatide found to be more cost-effective than semaglutide in patients with knee osteoarthritis, obesity

A microsimulation model was used to evaluate the cost-effectiveness of two glucagon-like peptide-1 receptor agonists (GLP1RAs), semaglutide and tirzepatide, for patients with osteoarthritis and obesity compared with usual ...

Current research may open doors to new treatments for children with juvenile dermatomyositis

Children with a rare, debilitating muscle disease could benefit from the findings of new research by experts at UCL and Great Ormond Street Hospital (GOSH).

Squishy 'smart cartilage' could target arthritis pain as soon as flareups begin

Researchers have developed a material that can sense tiny changes within the body, such as during an arthritis flareup, and release drugs exactly where and when they are needed.

Immune aging may be a driver of rheumatoid arthritis rather than a consequence

Features of immune system aging can be detected in the earliest stages of rheumatoid arthritis (RA), even before clinical diagnosis, a new study has found which provides at-risk individuals with hope for early intervention.

Common arthritis drug found to lower blood pressure and risk of heart disease

Methotrexate, a common medication used to treat rheumatoid arthritis, has a newly recognized useful secondary effect of lowering blood pressure and potentially reduces the risk of heart disease in people with this condition.

Noisy knees not an early arthritis sign, says new study

Knee crepitus, the sound of cracking or grinding in the knee joint, is very common across all age groups.

Q&A: These genetic insights into rheumatoid arthritis could help design better treatments

People with rheumatoid arthritis (RA) often have trouble getting out of bed in the morning, let alone getting to the rheumatologist for a checkup or participating in a research study. This makes a deeper understanding of ...

Benefits of long-term routine lab drug toxicity monitoring unclear in rheumatoid arthritis

For patients with rheumatoid arthritis (RA) using disease-modifying antirheumatic drugs (DMARDs), long-term routine laboratory toxicity monitoring (lt-RLTM) indicates that most very abnormal laboratory results are already ...

Survey reveals people are not aware knee and groin pain can be signs of hip problems

Having a hard time bending over to put your shoes on? Experiencing pain in the knees, groin, thigh or back? A survey by The Ohio State University Wexner Medical Center reveals many people don't realize these symptoms can ...

Back pain a $638 billion productivity black hole, Australian study warns

A new study from Monash University has revealed that long-term back problems will cost the Australian economy an estimated $638 billion in lost productivity over the next decade unless urgent action is taken.

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