May 2023 Medical Bulletin No. 5.

Published Date: 08 May 2023

The top medical stories of the day are as follows:A study suggests that early life abuse may increase the risk of adult premature death.

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Latest News

Enhancing Clinical Efficiency with AI to Prioritize Patient Care, with Ellen Gelles, MD Ellen Gelles, MD

Gelles discussed AI tools that are becoming a part of clinician’s armamentariums and the impact they are having on the field.

Addressing Community Health Needs for Comprehensive Care, with Mindy Hoang, MD Mindy Hoang, MD

Hoang discussed the CARD initiative started at Wayne State University in Detroit that she presented at the ACP IM 2025 meeting.

FDA Commissioner Marty Makary Resigns, Kyle Diamantas Steps In as Acting Head

FDA Commissioner Marty Makary Resigns, Kyle Diamantas Steps In as Acting Head

Experts Weigh Best Practices for Deprescribing

Nearly 3 in 10 Italians older than 65 years take more than 10 medications, highlighting why deprescribing is gaining attention as a strategy to improve care.

Experts Debate Combination Therapy for Pulmonary Fibrosis

Respiratory experts disagree over initiating upfront dual therapy vs sequential escalation as next-generation antifibrotics emerge for pulmonary fibrosis.

Keto Diet Boosts Liver Health More Than Others in Obesity

A ketogenic diet paired with weight loss improves liver health more than a Mediterranean or very low-fat diet with similar weight loss in people with metabolically unhealthy obesity.

Todays Updates

Trappsol Cyclo Misses Primary End Point in Phase 3 Trial for Niemann-Pick Disease Type C Isabella Ciccone, MPH

Findings from the phase 3 TransportNPC study showed that Trappsol Cyclo missed the primary end point in Niemann-Pick type C, but subgroup and survival data support planned 2026 NDA.

NeurologyLive® Friday 5 — October 2, 2026 Isabella Ciccone, MPH

Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending October 2, 2026.

Todays Updates

Trappsol Cyclo Misses Primary End Point in Phase 3 Trial for Niemann-Pick Disease Type C Isabella Ciccone, MPH

Findings from the phase 3 TransportNPC study showed that Trappsol Cyclo missed the primary end point in Niemann-Pick type C, but subgroup and survival data support planned 2026 NDA.

NeurologyLive® Friday 5 — October 2, 2026 Isabella Ciccone, MPH

Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending October 2, 2026.

Latest News

Gelles discussed AI tools that are becoming a part of clinician’s armamentariums and the impact they are having on the field.

Hoang discussed the CARD initiative started at Wayne State University in Detroit that she presented at the ACP IM 2025 meeting.

FDA Commissioner Marty Makary Resigns, Kyle Diamantas Steps In as Acting Head

Nearly 3 in 10 Italians older than 65 years take more than 10 medications, highlighting why deprescribing is gaining attention as a strategy to improve care.

Respiratory experts disagree over initiating upfront dual therapy vs sequential escalation as next-generation antifibrotics emerge for pulmonary fibrosis.

A ketogenic diet paired with weight loss improves liver health more than a Mediterranean or very low-fat diet with similar weight loss in people with metabolically unhealthy obesity.

News All Time

Three-Step Triage May Speed Assessment of Rheumatic Diseases

A three-step triage system may help reduce wait times for patients with inflammatory rheumatic and musculoskeletal disease, although it may still miss some diagnoses.

Breaking the Lab Habit: Rethinking Daily Hospital Testing

Not every patient needs routine daily testing. Breaking the habit can save money and improve patient health. But some habits are hard to break.

Cold Water Is Sufficient for Medical Handwashing

For healthcare handwashing, colder water appears just as effective as warm water, while also lowering resource use and Legionella risk.

Rheumatologists Seek Changes to Looming Medicaid Work Rules

Groups such as the ACR object to a CMS ‘frailty-exemption’ rule intended to make clinicians try to judge patients’ ability to work, noting among their objections a lack of adequate tools for this task.

Can Sexual Experience Reshape the Brain?

New research is exploring whether sexual experience may shape brain circuits linked to reward, learning, and mood — but the human evidence remains early.

Somatic Mutations Shape Systemic Autoinflammatory Disease

Acquired somatic variants may drive over 20% of systemic autoinflammatory disease diagnoses, with VEXAS syndrome and cryopyrin-associated periodic syndromes representing the majority of cases.

Sonographer Shortage Is Affecting Expectant Women’s Health

A sonographer shortage confronts expectant women in Ontario with long commutes for routine ultrasounds.

How Clinicians Can Improve STI Conversations

A Spanish sexologist says the key to better STI detection may be simpler than it seems: create a safe, nonjudgmental space and ask directly.

Ultrasound Expands Options for Chest Lesion Biopsy

A radiation-sparing procedure shows a safe and effective diagnostic potential.

Irish Health Service Operator Fined for Storing Data in Disused Bathroom, Turf Shed

Ireland's health service operator was fined a record amount for an Irish public body by the country's data regulator ⁠for storing medical records in "profound disarray" in...

How to Differentiate the Major Subtypes of ILD

The definitions of interstitial lung disease subtypes have undergone major revisions, encompassing clinical, radiologic, and histologic findings, as well as a few new categories.
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Size Matters for Chest Tubes

New data show similar outcomes with large-bore and small-bore chest tubes in patients with pneumothoraces.

UnitedHealthcare to Drop Prior Authorization Requirements for Range Of Conditions From Oct. 1

UnitedHealth's insurance unit said on Tuesday that a broad range of conditions will no ⁠longer need prior approval, effective October 1, as it aims to eliminate prior...
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