Validation of a new cancer-related VTE model

Published Date: 02 Mar 2023

The ONKOTEV score predicts the risk of venous thromboembolism in cancer patients.

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Latest News

Anti-VEGF Injections Safe Around CVD Events

Receiving anti VEGF eye injections around the time of a stroke or heart attack is not linked to an increased risk for death or major complications, a study finds.

Filtration Defect in Kidneys May Identify Heart Risk in T1D

Shrunken pore syndrome, a renal filtration defect, is associated with an increased risk for cardiovascular disease and death in patients with T1D without albuminuria.

GI Bleeding Deaths Rise in Wake of Increased DOAC Use

Deaths from gastrointestinal bleeding have increased, but fatal bleeding risk per anticoagulated patient has declined despite the widespread use of direct oral anticoagulants.

Placental Abruption Linked to Heart Disease in Teens

Cardiovascular disease shows up as early as within the first year of life.

Few Prescribing for Elevated Lp(a) in Low-Risk Patients

Most clinicians take no preventive action when a low-risk patient presents with elevated levels of lipoprotein(a), but 1 in 5 clinicians initiate preventive pharmacotherapy.

What Is Delaying Movement in Managing Gastroparesis?

Differing perspectives among gastric motility experts and regulatory roadblocks impede clinical care, but some companies are moving forward.

Todays Updates

Novel Psychedelic Promising on Resistant Depression

An investigative inhaled formulation of the psychedelic mebufotenin is linked to significant improvements in depression symptoms compared to placebo, a phase 2b trial shows.

Biocomputer From Human Neurons Plays Doom, Raises Ethics

A biological computer using human neurons learns Doom within 1 week, highlighting rapid adaptive learning and potential advantages over traditional AI systems.

Adding Chemo to Osimertinib Doubles PFS in Advanced NSCLC

The findings could fill a treatment gap for patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC) who also carry TP53 mutations.

EMA OKs Two Treatments for Small Cell Lung Cancer

Both drugs increase overall and progression-free survival.

Todays Updates

Novel Psychedelic Promising on Resistant Depression

An investigative inhaled formulation of the psychedelic mebufotenin is linked to significant improvements in depression symptoms compared to placebo, a phase 2b trial shows.

Biocomputer From Human Neurons Plays Doom, Raises Ethics

A biological computer using human neurons learns Doom within 1 week, highlighting rapid adaptive learning and potential advantages over traditional AI systems.

Adding Chemo to Osimertinib Doubles PFS in Advanced NSCLC

The findings could fill a treatment gap for patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC) who also carry TP53 mutations.

EMA OKs Two Treatments for Small Cell Lung Cancer

Both drugs increase overall and progression-free survival.

Latest News

Receiving anti VEGF eye injections around the time of a stroke or heart attack is not linked to an increased risk for death or major complications, a study finds.

Shrunken pore syndrome, a renal filtration defect, is associated with an increased risk for cardiovascular disease and death in patients with T1D without albuminuria.

Deaths from gastrointestinal bleeding have increased, but fatal bleeding risk per anticoagulated patient has declined despite the widespread use of direct oral anticoagulants.

Cardiovascular disease shows up as early as within the first year of life.

Most clinicians take no preventive action when a low-risk patient presents with elevated levels of lipoprotein(a), but 1 in 5 clinicians initiate preventive pharmacotherapy.

Differing perspectives among gastric motility experts and regulatory roadblocks impede clinical care, but some companies are moving forward.

News All Time

Light Activity May Reduce HBP Risk in Pregnancy

No need for strenuous exercise: Consistent, daily light activity can reduce hypertension risk in pregnant women by 30%.

High Blood Pressure Is Risky, Even for Young Adults

Young adults with systolic blood pressure that is 10 points higher than that of their peers have a 27% greater risk for heart disease and a 22% greater risk for kidney disease after age 40.

Premature Menopause Linked With Greater Risk for CHD

Menopause before age 40 is correlated with a much greater risk for coronary heart disease, and therefore cardiologists should consider earlier preventive measures for this population.

HIV Status Affects Pregnancy-Related Cardiac Changes

Pregnancy history is associated with significant differences in cardiac structure and function, which vary by HIV status.

Match Day 2026: Is Family Medicine Half-Full or Half-Empty?

As medical students learn where they’ll spend their residencies, it’s clear they’re gravitating toward programs in higher-paying fields or those offering more work-life balance.

CSP vs BiV Pacing Trials Show Inconsistent Results

Two multicenter trials drew different conclusions about the value of conduction system relative to biventricular pacing for left bundle branch block in heart failure.

Women With Metabolic Risks More Prone to Liver Fibrosis

Women with certain cardiometabolic risk factors face a disproportionately greater increase in the odds of clinically significant liver fibrosis than men.

PREVENT Score Alters Hypertension Treatment Over 65

A new analysis shows the 2025 hypertension guideline’s risk-based framework spares a small subgroup from immediate treatment.

Equation Choice May Affect CKD Staging in Primary Care

In the comparison of two equations for CKD stage classification in primary care, the CKD Epidemiology Collaboration equation places a higher proportion of patients in advanced stages.

Hormone Therapy Past Age 65 Tied to Cancer, Vascular Events

A large retrospective cohort study finds some cardiovascular benefits when HT is started earlier but generally supports guidelines discouraging use in older women.

Fast Metabolism May Signal Higher Diabetes Risk

Individuals with a higher estimated basal metabolic rate face a greater chance of developing diabetes and many of its complications, even after accounting for BMI, a study of 341,790 UK adults shows.

Preventing Sudden Death in Romano-Ward Syndrome

Romano-Ward syndrome, the most common congenital long QT disorder, often causes exertion- or stimulus-triggered syncope and sudden death; genetic testing and beta blockers guide prevention.

Why Is Extreme Heat a Mental Health Emergency?

As temperatures rise, so do sleepless nights, medication dangers, and social isolation, compounding vulnerability for those with mental illness.

Narrowing the Biological Age Gap Tied to Better Brain Health

Narrowing the gap between an individual’s biological and chronological age is linked to better brain health and a 23% reduced stroke risk, new research suggests.

Risk Score May Let Many With Chest Pain Skip Further Tests

The PROMISE minimal risk score identifies patients with recent-onset stable chest pain who can safely avoid extra testing and are less likely to have significant coronary disease or adverse events.

Frailty Index May Guide Blood Pressure Decision-Making

Frailty, rather than chronological age, more accurately distinguishes the ranges of systolic blood pressure that are linked to a lower risk for adverse cardiac events in patients with hypertension.

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