Validation of a new cancer-related VTE model

Published Date: 02 Mar 2023

The ONKOTEV score predicts the risk of venous thromboembolism in cancer patients.

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Can Medical Evidence Be Trusted Without Scrutiny?

Published findings may be affected by methodological issues, reporting choices, and financial interests, highlighting the need for clinicians to carefully assess the evidence.

When to Screen Older Patients for Valve Disease?

Some experts are encouraging patients older than 65 years to get screened for heart valve failure, even as research lags on the benefits of population screening programs.

GLP-1 Therapy and OSA: Promise, But Limits

Tirzepatide improves apnea severity and weight in SURMOUNT-OSA, but experts say many patients still have residual disease and long-term data are needed.

Biomarkers May Help Predict PAP Benefit in Sleep Apnea

Two biomarkers, hypoxic burden and heart rate response, may help identify patients with obstructive sleep apnea who may derive greater cardiovascular benefits from long-term PAP therapy.

Childhood Reasoning Tied to Lower Later-Life Dementia Risk

Higher childhood inductive reasoning ability is associated with a lower risk for dementia decades later.

Tampons Have Traces of Lead: Does it Matter?

While levels of lead released from tampons are low, the amount absorbed into the body and its effects on health are unclear.

Todays Updates

First-Line Combo Therapies Best Chemo Alone in NSCLC Trials

New phase 3 data add to a growing number of EGFR-directed first-line options for advanced NSCLC with EGFR exon 20 insertions.

3D Mammography Improves Long-Term Cancer Risk Prediction

Researchers develop and validate a deep learning model using longitudinal 3D tomosynthesis examinations to predict individualized 5-year risk for breast cancer.

Todays Updates

First-Line Combo Therapies Best Chemo Alone in NSCLC Trials

New phase 3 data add to a growing number of EGFR-directed first-line options for advanced NSCLC with EGFR exon 20 insertions.

3D Mammography Improves Long-Term Cancer Risk Prediction

Researchers develop and validate a deep learning model using longitudinal 3D tomosynthesis examinations to predict individualized 5-year risk for breast cancer.

Latest News

Published findings may be affected by methodological issues, reporting choices, and financial interests, highlighting the need for clinicians to carefully assess the evidence.

Some experts are encouraging patients older than 65 years to get screened for heart valve failure, even as research lags on the benefits of population screening programs.

Tirzepatide improves apnea severity and weight in SURMOUNT-OSA, but experts say many patients still have residual disease and long-term data are needed.

Two biomarkers, hypoxic burden and heart rate response, may help identify patients with obstructive sleep apnea who may derive greater cardiovascular benefits from long-term PAP therapy.

Higher childhood inductive reasoning ability is associated with a lower risk for dementia decades later.

While levels of lead released from tampons are low, the amount absorbed into the body and its effects on health are unclear.

News All Time

The Dark Side of Full Patient Autonomy

Amid the backlash against paternalism and efforts to rebuild trust, an important ethical principle got caught in the fallout: the duty to act in the patient’s best interest.

CDK4/6 Inhibitors: One Class, Three Outcomes

Abemaciclib and ribociclib now show adjuvant survival benefit; palbociclib didn't. Laura Spring, MD, on picking the right agent per patient.

JAK Inhibitors Linked to Reduced Disease Activity in RA

JAK inhibitors are linked to reduced disease activity and improved patient-reported outcomes in patients with rheumatoid arthritis, regardless of diabetes, cardiometabolic burden, or age.

IL-6 May Predict HF Risk in Adults With Obesity and Diabetes

Higher interleukin 6 concentrations are linked to an increased risk for heart failure in adults with type 2 diabetes and overweight or obesity.

Global Definition Breaks MI Into Three Clinical Categories

A new global definition of myocardial infarction will allow cardiologists and other healthcare professionals to improve diagnosis and treatment of patients with the disorder.

‘I Had to Choose’: When Your Medical Career Isn’t Fulfilling

For physicians, a fulfilling career often starts with unlearning the habits that made them successful in medicine — and finding the courage to try.

Normothermia After Cardiac Arrest Tied to Improved Survival

A near-normal peak temperature after in-hospital cardiac arrest is linked to higher survival rates than lower or higher temperature ranges.

Inappropriate Prescribing Cascades Put Older Adults at Risk

Drugs used commonly in older adults can cause side effects that trigger cascades of new prescriptions, potentially causing harm.

High or Low Testosterone May Raise Atrial Fibrillation Risk

A narrative review of the link between testosterone levels and atrial fibrillation in men suggests a U-shaped relationship; however, more research is needed.

Intense Septal LGE on Cardiac MRI Flags Cardiac Amyloidosis

Intense late gadolinium enhancement of the interatrial septum on cardiac MRI offers a highly specific marker to differentiate cardiac amyloidosis from other cardiomyopathies.

Muscle Loss on GLP-1s: Data and Debate

Muscle loss during GLP-1 therapy sparked a lively debate at the 2026 ADA Scientific Sessions. Here's what the data show, who's at risk, and how to counsel patients.

Where You Live May Shape Sleep Apnea Outcomes

Patients with obstructive sleep apnea who live in disadvantaged neighborhoods experience more severe sleep-related hypoxemia and have a higher risk for cardiovascular events.

CGM Looks Perfect. A1c Doesn't. Which One Is Right?

CGM and A1c increasingly disagree, especially with AID pumps. When should clinicians trust time in range over A1c? The evidence, the guideline gaps, and access disparities in type 1 and 2 diabetes.

Stroke Risk Peaks in the 3 Months After Cancer Diagnosis

The magnitude of the risk varies widely by cancer type, being highest for patients with lung or pancreatic cancers.

Routine Liver Markers May Signal Future Cardiovascular Risk

Elevated markers of liver fat, fibrosis, and functional decline are associated with an increased risk for cardiovascular disease in people without clinical liver disease at baseline.

Functional Angio Wins in Multivessel STEMI

Functional angiography is linked to a 38% lower risk for the primary outcome over conventional angiography in STEMI patients with multivessel disease.

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