Validation of a new cancer-related VTE model

Published Date: 02 Mar 2023

The ONKOTEV score predicts the risk of venous thromboembolism in cancer patients.

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AF Screening May Flag Increased HF Risk

Researchers quantify the risk for heart failure among people who screen positive for atrial fibrillation and suggest ECG could be warranted.

Graham Steell: Bedside Cardiology Before the ECG

In an era without ECG or routine x ray, Graham Steell linked heart sounds and pulse tracings to pathology, showing how careful bedside observation can still shape diagnosis.

Culture-Negative Endocarditis Shows Distinct Patterns

Patients with culture-negative infective endocarditis differ in presentation and features of the disease from those with culture-positive infective endocarditis but have similar survival outcomes.

Unexpected Results Lead to Questions on IVUS-Guided PCI

When IVUS did not outperform angiography for guiding percutaneous interventions in two trials, the results offered more questions than answers.

Poststroke Virtual Therapy No Better Than Standard Care

Early high-dose, high-intensity virtual exploratory movement therapy is not superior to standard care for hand and arm recovery after stroke, a new phase 2 trial suggests.

Well-Known Cardiac Marker Signals Kidney Decline in Diabetes

B-type natriuretic peptide shows a graded association with decline in kidney function in individuals with diabetes, even at concentrations ≤ 18.4 pg/mL, which are conventionally considered normal.

Todays Updates

Where Does Mistletoe Extract Fit in Supportive Cancer Care?

Mistletoe therapy may improve the QOL of patients with cancer; however, evidence does not support a survival benefit, limiting its role in routine oncology care.

A Chemo-Free Option for Some Advanced Endometrial Cancers?

A phase 2 study suggests that immunotherapy plus radiation could spare some patients with advanced endometrial cancer from chemotherapy.

Todays Updates

Where Does Mistletoe Extract Fit in Supportive Cancer Care?

Mistletoe therapy may improve the QOL of patients with cancer; however, evidence does not support a survival benefit, limiting its role in routine oncology care.

A Chemo-Free Option for Some Advanced Endometrial Cancers?

A phase 2 study suggests that immunotherapy plus radiation could spare some patients with advanced endometrial cancer from chemotherapy.

Latest News

Researchers quantify the risk for heart failure among people who screen positive for atrial fibrillation and suggest ECG could be warranted.

In an era without ECG or routine x ray, Graham Steell linked heart sounds and pulse tracings to pathology, showing how careful bedside observation can still shape diagnosis.

Patients with culture-negative infective endocarditis differ in presentation and features of the disease from those with culture-positive infective endocarditis but have similar survival outcomes.

When IVUS did not outperform angiography for guiding percutaneous interventions in two trials, the results offered more questions than answers.

Early high-dose, high-intensity virtual exploratory movement therapy is not superior to standard care for hand and arm recovery after stroke, a new phase 2 trial suggests.

B-type natriuretic peptide shows a graded association with decline in kidney function in individuals with diabetes, even at concentrations ≤ 18.4 pg/mL, which are conventionally considered normal.

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Lower LDL-C Target May Improve CV Outcomes

A study finds direct evidence to support guideline changes that promote lower targets for low-density lipoprotein cholesterol.

BP Lower Than Target in Many With Coronary Heart Disease

Over one third of patients with coronary heart disease have blood pressure below targets recommended by European guidelines and have elevated risks for heart and kidney diseases.

Can Remote Pressure Monitoring Lower HF Hospitalisation?

A wireless implantable device that remotely monitors pulmonary artery pressure offers reliable safety and is linked to a significant reduction in the risk for heart failure-related hospitalisation.

Does Pregnancy Loss Signal Future Heart Disease?

A history of stillbirth or miscarriage is linked to an increased risk for cardiovascular disease in women.

Surgery Benefits Heart Health in Mild Cortisol Excess

In patients with mild autonomous cortisol secretion, adrenalectomy provides comprehensive cardiovascular benefits, improving blood pressure, cardiac structure, and coagulation profile.

Exercise Intensity Over Volume Linked to Lower Disease Risks

Higher intensity of physical activity, regardless of total volume, is linked to significantly lower risks for many cardiovascular and other chronic diseases and death.

Genetic Risk Tied to Postpartum BP Risk, BMI Matters More

First-time mothers with high genetic risk for systolic blood pressure have a higher likelihood of postpartum hypertension, but BMI and hypertensive pregnancy disorders are stronger risk factors.

AI Model Can Help Cut Hospitalizations in Dialysis Patients

AI-driven interventions reduce the odds of hospitalization within 7 days by 8% in patients with end-stage kidney disease receiving hemodialysis, according to a recent study.

The Case for Muscle Power Over Strength

The ability to move a weight with force may be a better predictor of mortality risk than how much weight you can move overall. A beneficial tweak for exercise Rx?

Apixaban May Cut Stroke Risk but Raise Bleeding in Dialysis

Observational data suggest apixaban leads to fewer thromboembolic events but higher bleeding risk, highlighting the need for individualized decision-making in dialysis patients.

Wall Thickness Heterogeneity Improves Cardiomyopathy Detection

Heterogeneity in the thickness of the heart wall, represented by wall thickness standard deviation, can improve the early detection of hypertrophic cardiomyopathy and mutation carriers, a study shows.

Stable Patients May Safely End Beta-Blockers Post-MI

Stable patients who stop taking beta-blockers a year or more after a heart attack fare no worse than those who keep taking them, a study conducted in South Korea finds.

Empagliflozin May Boost Exercise Tolerance in T2D

In patients with type 2 diabetes, 6 months of empagliflozin therapy vs sitagliptin therapy is tied to a modest increase in the fat oxidation rate during exercise of low-to-moderate intensity.

Veterans Often Miss Out on Quadruple Therapy for HFrEF

Most US veterans who have new heart failure with reduced ejection fraction do not receive all four classes of guideline-directed medical therapy, and many die before starting full therapy, a study finds.

PVR Reduced in Adults With HFpEF, Pulmonary Hypertension

In a phase 2 trial, treatment with sotatercept shows reduced pulmonary vascular resistance and heart outcomes in patients with combined postcapillary and precapillary pulmonary hypertension and HFpEF.

Should Your Patient Be on Statins? Maybe the Eyes Can Tell

A trial of an AI algorithm that uses retina images to evaluate the risk for atherosclerotic cardiovascular disease demonstrates a high level of accuracy.

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Patients with head and neck cancer who cannot receive cisplatin now have new hope.

Adding Chemo to Osimertinib Doubles PFS in Advanced NSCLC

Stem Cell Selection Unneeded for SSc Transplant Therapy?

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