Validation of a new cancer-related VTE model

Published Date: 02 Mar 2023

The ONKOTEV score predicts the risk of venous thromboembolism in cancer patients.

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Latest News

IL-6 May Predict HF Risk in Adults With Obesity and Diabetes

Higher interleukin 6 concentrations are linked to an increased risk for heart failure in adults with type 2 diabetes and overweight or obesity.

Global Definition Breaks MI Into Three Clinical Categories

A new global definition of myocardial infarction will allow cardiologists and other healthcare professionals to improve diagnosis and treatment of patients with the disorder.

‘I Had to Choose’: When Your Medical Career Isn’t Fulfilling

For physicians, a fulfilling career often starts with unlearning the habits that made them successful in medicine — and finding the courage to try.

Normothermia After Cardiac Arrest Tied to Improved Survival

A near-normal peak temperature after in-hospital cardiac arrest is linked to higher survival rates than lower or higher temperature ranges.

Inappropriate Prescribing Cascades Put Older Adults at Risk

Drugs used commonly in older adults can cause side effects that trigger cascades of new prescriptions, potentially causing harm.

High or Low Testosterone May Raise Atrial Fibrillation Risk

A narrative review of the link between testosterone levels and atrial fibrillation in men suggests a U-shaped relationship; however, more research is needed.

Todays Updates

Definium's LSD-based Anxiety, Depression Drug Scores Another Trial Win

Definium Therapeutics said on Monday its LSD-based treatment reduced symptoms of generalized anxiety disorder ⁠in a second successful late-stage study for the...

Brain MRI Surveillance Alone May Be Enough in SCLC

For patients with small-cell lung cancer, skipping preventive cranial radiotherapy in favor of MRI monitoring may improve outcomes.

Todays Updates

Definium's LSD-based Anxiety, Depression Drug Scores Another Trial Win

Definium Therapeutics said on Monday its LSD-based treatment reduced symptoms of generalized anxiety disorder ⁠in a second successful late-stage study for the...

Brain MRI Surveillance Alone May Be Enough in SCLC

For patients with small-cell lung cancer, skipping preventive cranial radiotherapy in favor of MRI monitoring may improve outcomes.

Latest News

Higher interleukin 6 concentrations are linked to an increased risk for heart failure in adults with type 2 diabetes and overweight or obesity.

A new global definition of myocardial infarction will allow cardiologists and other healthcare professionals to improve diagnosis and treatment of patients with the disorder.

For physicians, a fulfilling career often starts with unlearning the habits that made them successful in medicine — and finding the courage to try.

A near-normal peak temperature after in-hospital cardiac arrest is linked to higher survival rates than lower or higher temperature ranges.

Drugs used commonly in older adults can cause side effects that trigger cascades of new prescriptions, potentially causing harm.

A narrative review of the link between testosterone levels and atrial fibrillation in men suggests a U-shaped relationship; however, more research is needed.

News All Time

Prasugrel Falls Short as Default P2Y12 Inhibitor for ACS

It is nearly 20 years since trials of prasugrel and ticagrelor showed better protection over clopidogrel against MACE for ACS, but superiority of one over the other still remains unresolved.

Hormone Therapy: Lower Heart Risk in Women With Hot Flashes

In perimenopausal and recently postmenopausal women experiencing hot flashes and/or night sweats, initiating hormone therapy is associated with a reduction in the risk for cardiovascular events.

Severe Infections Tied to Heart Failure Risk

A hospitalization for severe infection is associated with a higher long-term risk of developing heart failure, yet current risk calculators may underestimate this risk by as much as 9%.

CAC Found to Add Little to PREVENT-ASCVD Risk Prediction

Adding coronary artery calcium to the PREVENT-ASCVD equations only modestly improves risk prediction overall, with the greatest reclassification seen in borderline-risk adults.

More Breast Milk in Infant Diet Aids Maternal Heart Health

A breast milk diet for infants is associated with a dose-response relationship to lower triglyceride levels in mothers.

Xylitol Linked to Increased Long-Term Cardiovascular Risk

The results are likely to sharpen debate over how clinicians should counsel patients about nonsugar sweeteners.

Combined A1c, BP Time in Range Predicts Kidney Outcomes

Patients who maintain target A1c and systolic blood pressure 100% of the time for a year have significantly better kidney outcomes than those in target range 50% of the time or less.

How Common Is Doping in Amateur Sports?

Amateur athletes may underestimate the risks for performance-enhancing substances, highlighting the need for better education and coordinated support from healthcare professionals.

Gestational Age Predicts Neurodevelopmental Outcomes in CHD

Premature infants with congenital heart disease may have worse cognitive and motor development outcomes than those born at term, a cohort study shows.

Persistently High Troponin-T Levels in ACS Tied to HF Risk

Persistently elevated troponin-T levels are linked to a higher risk for heart failure in patients with suspected acute coronary syndrome, a study finds.

PPIs: What Rigorous Data Actually Confirms

Ten PPI products share the same warnings on kidney disease, dementia, fracture, and cancer. Daniela Jodorkovsky, MD, on why study design keeps overturning the alarm.

PARP Inhibitors: Narrower Labels, Wider Reach

Five branded products, four tumor types, and a regulatory arc that walked back late-line ovarian approvals even as AKEEGA just reached hormone-sensitive prostate cancer.

Cardiometabolic Risks Arise Early After Gestational Diabetes

Gestational diabetes is linked to an increased risk for type 2 diabetes and other cardiometabolic conditions within the first few years postpartum.

Cold Weather and Cardiovascular Risk: Does Climate Matter?

A large Brazilian study suggests colder temperatures may increase cardiovascular hospitalizations, while regional climate differences did not appear to change the association.

NICE Expands Drug Access for Young Children With NF1 Tumours

Trial data behind the decision showed durable tumour shrinkage and improved pain outcomes with mirdametinib, now recommended by NICE for children from age 2.

Response-Guided Therapy Trims Antibiotic Use in Endocarditis

Stopping antibiotics at clinical stabilisation in patients with left-sided endocarditis yields more days off therapy than standard regimens but is linked to a higher rate of relapse, a trial finds.

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