Study: Cholesterol was lowered with an oral PCSK9 inhibitor.

1 in 5 Kids on Long-Term VADs Still Supported at 2 Years

Nearly 1 in 5 children with ventricular assist devices remain on support for more than 6 months, and among that group, 1 in 5 patients are still on the device at 2 years.

ECG Biomarker Predicts Atrial Fibrillation Risk Post-Stroke

Periodic repolarization dynamics, a novel ECG-derived biomarker, helps identify patients at an elevated risk for atrial fibrillation after acute ischemic stroke.

OSA Linked to Higher Risk for Heart Failure in Cancer

Cancer patients with obstructive sleep apnea face a higher risk for heart failure, with women experiencing the most pronounced increase in risk.

Beta-3 Agonist Shows Promise for Kids With Bladder Issues

Mirabegron, a beta-3 agonist, appears safe and effective for children with bladder problems.

Dengue Patients on DAPT or OAC Face More Frequent Bleeding

Among patients with acute dengue infection, those already on dual antiplatelet or oral anticoagulant therapies experience major bleeding more often than those not on antithrombotic therapy.

Are Beef Tallow and Zone 2 Training Worth the Hype?

Evidence supports replacing saturated fat with unsaturated fat and improving cardiorespiratory fitness, but neither trend has evidence for the categorical claims made online.

Early Menopause Leaves Lasting Trace on Brain

Antiplatelet Therapy vs Thrombolysis in Spinal Infarction

In spontaneous spinal cord infarction, standard antiplatelet therapy was associated with significantly lower all-cause mortality compared with thrombolytic treatment.

SCA Shown to Strike Young Athletes Mostly During Training, Practice

A new study highlights the need to expand emergency response efforts for sudden cardiac arrest in young athletes.

Heart Imaging Measures May Flag SCD Risk in HFmrEF

The extent of late gadolinium enhancement and tissue damage on cardiac imaging may help predict risk for sudden cardiac death in patients with heart failure with mildly reduced ejection fraction.

Heart Stress May Predict CVD and Death Risks in Older Adults

Developing or continuing to experience heart stress over time is associated with increased risks for cardiovascular disease and death in older adults.

Deep Dive: SSRIs: Precision Rx Meets the Deprescribing Question

The largest pharmacogenomic SSRI trial yet meets a deprescribing evidence base that cuts both ways; psychologist John Read still calls current prescribing patterns a public health problem.

Vascular Disease May Raise Apathy Risk in People With HIV

Vascular disease is independently associated with more frequent and severe symptoms of apathy among people with HIV.

CKM Syndrome Tied to Major Blinding Eye Diseases

Cardiovascular-kidney-metabolic syndrome is associated with an increased risk of developing major blinding eye diseases in a large UK cohort, with stage 3 showing the highest rates.

Late Bleeding Events After PCI Tied to Higher Death Risk

After PCI, both ischaemic and bleeding complications are tied to a higher risk for death, but bleeding events occurring months after discharge carry a higher risk for death than late ischaemic events.

1-Year Tirzepatide, Ixekizumab Combo Trial Results Reported

Results from phase 3b trials show a greater benefit at 52 weeks for patients with psoriasis or psoriatic arthritis treated with ixekizumab plus tirzepatide vs ixekizumab alone.