Atopic Dermatitis Systemic Therapies are topped by upadacitinib 30 mg in meta-analyses.

Published Date: 04 May 2023

Updated analysis of more than a dozen clinical trials evaluating upadacitinib as a monotherapy systemic treatment for atopic dermatitis reveals the drug's highly pervasive skin-clearing efficacy.

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Frailty May Modify Late-Life Hypertension-Dementia Risk

Late-life hypertension is associated with a higher risk for dementia in healthy older adults but not in those with prefrailty or frailty, a new study shows.

Air Travel and Venous Thromboembolism: Who Is at Risk?

Experts recommend individualized VTE prevention for travelers at increased risk, emphasizing movement, hydration, compression stockings, and selective anticoagulant use.

Breast RT: Coronary Artery Dose Better Predicts Cardiac Risk

For patients who receive heart-sparing radiotherapy for breast cancer, coronary artery dose is key in the risk for future cardiac events.

Advanced ML Model Predicts Onset of Epilepsy and Depression

A large study applies advanced machine learning to identify shared risk factors and predictors of disease onset in patients with epilepsy and depression.

5D MRI Cuts Scan Time of Heart Imaging in Congenital Disease

A gadolinium-enhanced five-dimensional MRI technique provides a significantly faster and simplified whole-heart imaging approach for evaluating patients with congenital heart disease.

Nearly 1 in 10 With Primary Biliary Cholangitis Have CKD

Chronic kidney disease affects nearly 1 in 10 patients with primary biliary cholangitis, and its presence is linked to an increased risk for mortality.

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Advancing Care in ES-SCLC: Personalized Strategies, New Therapies, and Real-World Insights

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Belzutifan and pembrolizumab together reduced the risk of disease recurrence or death

FDA Approves Prostate Cancer Combo That Warranted Advisory Meeting

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Talquetamab Regimens Boost Survival in Multiple Myeloma

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A combination of clinician and patient prompts worked best, but talks remained infrequent

Todays Updates

Enhancing Comprehensive Biomarker Testing and Biomarker-Directed Treatment Selection

Enhancing Comprehensive Biomarker Testing and Biomarker-Directed Treatment Selection

Advancing Care in ES-SCLC: Personalized Strategies, New Therapies, and Real-World Insights

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Adjuvant Combination for Kidney Cancer Gets FDA's Blessing

Belzutifan and pembrolizumab together reduced the risk of disease recurrence or death

FDA Approves Prostate Cancer Combo That Warranted Advisory Meeting

Capivasertib plus abiraterone combination lands indication for PTEN-deficient tumors

Talquetamab Regimens Boost Survival in Multiple Myeloma

"Combinations represent additional options for early-line treatment," researcher says

In High-Risk B-Cell ALL, Swapping Out Chemo for Blinatumomab Improves Outcomes

The bispecific T-cell engager also reduced toxicity in newly diagnosed kids

Timely 'Nudges' Can Help Encourage More End-of-Life Conversations in Cancer

A combination of clinician and patient prompts worked best, but talks remained infrequent

Latest News

Late-life hypertension is associated with a higher risk for dementia in healthy older adults but not in those with prefrailty or frailty, a new study shows.

Experts recommend individualized VTE prevention for travelers at increased risk, emphasizing movement, hydration, compression stockings, and selective anticoagulant use.

For patients who receive heart-sparing radiotherapy for breast cancer, coronary artery dose is key in the risk for future cardiac events.

A large study applies advanced machine learning to identify shared risk factors and predictors of disease onset in patients with epilepsy and depression.

A gadolinium-enhanced five-dimensional MRI technique provides a significantly faster and simplified whole-heart imaging approach for evaluating patients with congenital heart disease.

Chronic kidney disease affects nearly 1 in 10 patients with primary biliary cholangitis, and its presence is linked to an increased risk for mortality.

News All Time

Breastfeeding Linked to Lower Cardiometabolic Risk in PMOS

Exclusive breastfeeding is associated with a significant reduction in the cardiometabolic risk among women with polyendocrine metabolic ovarian syndrome after high-risk pregnancies.

Ultrasound Spots Heart Muscle Stiffening in Aortic Stenosis

Ultrafast ultrasound shear wave elastography may offer a feasible and non-invasive method to detect the stiffening of heart muscle in patients with congenital aortic stenosis, a study finds.

Cardiometabolic Issues: When to Suspect Sleep Apnea

Obstructive sleep apnea could be hiding behind subtle symptoms and uncontrolled cardiometabolic disease.

AI-Assisted POCUS Helps NPs, PAs Make Faster Cardiac Calls

New technology offers the ability for bed-side scans.

People Living Together Share More Oral and Gut Microbiota

People with close family ties who live together share more oral and gut microbes with each other than with other people in their communities.

National AI Initiative Promising for Canadian Healthcare

Canada's new national AI strategy, "AI for All," aims to build trust, expand opportunities, and ensure that AI is used responsibly in healthcare and other industries.

Vitamin K2 Supplementation May Curb Coronary Calcification

Supplementation with vitamin K2 may help slow the progression of coronary artery calcification among people with mild coronary artery disease.

Post-Deprescribing, Do Older Adults Get Inappropriate Meds?

When substitutions occur, more than 1 in 4 involve a potentially inappropriate medication.

WHO Urges Europe to Strengthen Preparedness for Extreme Heat

Updated WHO guidance urges clinicians and health systems to identify vulnerable individuals early and strengthen prevention before extreme heat drives illness and death.

Are Medical Schools Doing Enough to Teach Clinical AI?

As new clinical AI tools proliferate, students are growing worried about the burden of keeping up. Are medical schools doing enough to train them?

How Donors Died May Not Matter for Heart Transplant Outcomes

Recipients of heart transplants have similar 10-year survival and graft health outcomes, regardless of whether hearts are obtained from donors after circulatory death or brain death, a study finds.

A Common Phone Metric May Be Brain Health’s Next Frontier

New research linking heart rate variability to glymphatic clearance could lead to a simple new biomarker of dementia risk.

Why Primary Hyperaldosteronism Remains Underdiagnosed

Primary hyperaldosteronism may account for a sizable share of resistant hypertension, yet experts say most cases still go undiagnosed despite clear treatment options.

Sleepy Days and Restless Nights Linked to Hypertension Risk

Adults who report excessive daytime sleepiness and difficulty falling asleep face more than triple the risk of developing hypertension.

HFpEF Diagnosis Enters a New Era

New imaging tools, exercise testing, and phenotype-based therapy are reshaping how clinicians diagnose and treat HFpEF.

Roosevelt’s Public Image and Overlooked Illness

A 2023 review reexamines Yalta through a medical lens, showing how Roosevelt’s deteriorating cardiovascular status may have been underestimated.

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