Drug restores heart muscle elasticity in mouse model of age-related heart failure

Published Date: 18 Oct 2025

Michael Gotthardt at the Max Delbrück Center and collaborators are developing a drug to treat a common type of heart failure characterized by impaired cardiac filling. In a recent study, his group and a US team showed the ...

Read Full News

Latest News

Migraine Tied to Earlier Stroke, Better Recovery

Migraine is linked to an earlier onset of stroke, yet young patients with stroke and a history of migraine experience better functional recovery at discharge.

Resistance Training May Lower Risk for T2D

An analysis using data from three long-running studies on the effect of lifestyle and health provides more support for consistent use of resistance training with aging.

Metabolic Issues Show Up Early and Often With ARPI Therapy

A new study underscores the importance of monitoring patients’ cardiometabolic health soon after starting ADT plus ARPI therapy for prostate cancer.

Brain Networks Tied to Post-Stroke Dizziness

A lesion network analysis reveals cerebellar and occipital regions consistently associated with dizziness after ischemic stroke, regardless of lesion location or symptom subtype.

Women Make Up Small Percentage of Trial Leaders for SHD

Women make up less than 10% of oversight committee seats for interventional structural heart disease trials, although women are being studied more intently than ever before.

AI Stethoscopes May Aid Early CVD Detection

AI-powered stethoscopes are showing promise in primary care, with new evidence suggesting improved detection of heart failure, atrial fibrillation, and valvular disease.

Todays Updates

Many Clinical Paths Are Open to NPs. Here’s Help in Picking

‘A strength of the nurse practitioner profession is its versatility,’ one expert says.

Nurses Speak Out on Burnout, Mandatory Overtime, and Burning the Candle at Both Ends

Emotionally drained, sleep-deprived, and skipping meals to keep up: what nurse leaders say needs to change to prevent burnout.

Most Family Physicians Struggle With After-Hours Admin Work

Most family physicians face heavy administrative burden, but improved electronic health records and staff support may help to ease some of the load.

'Just Bloating': Stop Dismissing This Common GI Complaint

Bloating is one of patients' most common gastrointestinal complaints. Dr Alicia Muratore kicks off this six-part series by asking why bloating is often treated as an afterthought.

S1 Episode 4: Urinary Tract Infections and Sexual Function

Drs Anne Lenore Ackerman and Rachel S. Rubin discuss urinary tract infections, sexual function, quality of life, and the importance of patient education.

Immunotherapy Promises New Era in Cancer Prevention

Prof David Kerr explores whether PD-1 inhibitors and targeted vaccines can regress polyps and prevent secondary cancers in Lynch syndrome.

HF Hospitalizations and Telehealth Coverage Parity Laws

State telehealth coverage parity laws require private insurers to cover outpatient telehealth visits increasing access for HF patients. This analysis examines whether this affected clinical outcomes.

Todays Updates

Many Clinical Paths Are Open to NPs. Here’s Help in Picking

‘A strength of the nurse practitioner profession is its versatility,’ one expert says.

Nurses Speak Out on Burnout, Mandatory Overtime, and Burning the Candle at Both Ends

Emotionally drained, sleep-deprived, and skipping meals to keep up: what nurse leaders say needs to change to prevent burnout.

Most Family Physicians Struggle With After-Hours Admin Work

Most family physicians face heavy administrative burden, but improved electronic health records and staff support may help to ease some of the load.

'Just Bloating': Stop Dismissing This Common GI Complaint

Bloating is one of patients' most common gastrointestinal complaints. Dr Alicia Muratore kicks off this six-part series by asking why bloating is often treated as an afterthought.

S1 Episode 4: Urinary Tract Infections and Sexual Function

Drs Anne Lenore Ackerman and Rachel S. Rubin discuss urinary tract infections, sexual function, quality of life, and the importance of patient education.

Immunotherapy Promises New Era in Cancer Prevention

Prof David Kerr explores whether PD-1 inhibitors and targeted vaccines can regress polyps and prevent secondary cancers in Lynch syndrome.

HF Hospitalizations and Telehealth Coverage Parity Laws

State telehealth coverage parity laws require private insurers to cover outpatient telehealth visits increasing access for HF patients. This analysis examines whether this affected clinical outcomes.

Latest News

Migraine is linked to an earlier onset of stroke, yet young patients with stroke and a history of migraine experience better functional recovery at discharge.

An analysis using data from three long-running studies on the effect of lifestyle and health provides more support for consistent use of resistance training with aging.

A new study underscores the importance of monitoring patients’ cardiometabolic health soon after starting ADT plus ARPI therapy for prostate cancer.

A lesion network analysis reveals cerebellar and occipital regions consistently associated with dizziness after ischemic stroke, regardless of lesion location or symptom subtype.

Women make up less than 10% of oversight committee seats for interventional structural heart disease trials, although women are being studied more intently than ever before.

AI-powered stethoscopes are showing promise in primary care, with new evidence suggesting improved detection of heart failure, atrial fibrillation, and valvular disease.

News All Time

Dapagliflozin Reduces AKI After Cardiac Surgery

Four doses of the SGLT2 inhibitor dapagliflozin reduce acute kidney injury risk after elective cardiac surgery, with a low incidence of ketoacidosis.

Dexrazoxane May Preserve LV Function in Cancer Survivors

Researchers analyzed echocardiographic data from patients who received dexrazoxane before doxorubicin as part of their treatment for cancer in childhood.

Photon-Counting CT Boosts Stent Fracture Detection

A phantom study shows that photon-counting detector CT significantly improves the detection of visceral endovascular stent fractures compared with conventional CT.

Postpartum Health Coaching Boosts Blood Pressure Control

Health coaching may help close a critical gap in care after a hypertensive pregnancy.

Five Steps to Earlier Heart Failure Detection

Heart failure often hides behind vague complaints. These five primary care steps can help spot it earlier and guide faster, evidence-based treatment.

How to Talk About Exercise When Weight Loss Is Off the Table

In the era of GLP-1 drugs, weight loss is no longer a compelling pitch. Here’s how to reframe physical activity for patients.

Central Adiposity May Reclassify CVD Risk Beyond BMI

Among individuals with normal BMI, elevated waist circumference or waist-to-hip ratio may identify cardiovascular risk beyond BMI.

Allopurinol Offers No Heart Benefit in Kidney Donors

The use of allopurinol leads to significantly lower uric acid levels but shows no effect on heart mass, blood pressure, or insulin sensitivity in healthy living kidney donors, a phase 2b trial finds.

Retatrutide Trims Weight and A1c in Diabetes

Retatrutide helped patients lose up to 30% of body weight in new trials, among the largest effects yet from a weight-loss drug – but a new safety signal raises questions.

Quarter of Gestational Diabetes Moms Get Early Hypertension

More than 1 in 4 women with recent gestational diabetes developed hypertension at 5 months postpartum, driven primarily by baseline maternal characteristics rather than pregnancy complications.

Cardiometabolic Index Can Predict Mortality Risk in T2D

A higher cardiometabolic index is linked to an increased risk for all-cause and cardiovascular mortality in patients with T2D, serving as an effective prognostic tool.

Three Midlife Risk Factors Linked to Earlier Dementia Onset

Smoking, diabetes, and hypertension in midlife are associated with nearly 13 fewer dementia-free years, underscoring the importance of vascular risk management.

Even Low Physical Activity May Lower Stroke Risk in AF

Even low levels of physical activity were linked to lower stroke and mortality risks in atrial fibrillation, with greater benefits generally seen at higher activity levels.

Timing of Thrombolysis Matters in Patients With Mild Stroke

In patients with ischaemic stroke, intravenous thrombolysis given within 90 minutes of symptom onset improves functional outcomes, but the benefit fades progressively beyond this window.

BP Variability Tied to White Matter Lesion Growth

Higher visit-to-visit variability in systolic blood pressure is linked to faster progression of white matter lesions in patients at high cardiovascular risk, a study finds.

Iron Testing Gap Seen in Patients With New Heart Failure

Iron deficiency testing remains inconsistent among patients with incident heart failure in UK primary care, with variation by age, sex, and presence of long-term conditions.

Recommended News For You

Classifying childhood brain cancers by immune response may improve diagnostics and treatments

Vepdegestrant Earns FDA Nod for ESR1-Mutated Breast Cancer

In inflammatory breast cancer, ER beta regulates estrogen signaling.

Survivors of childhood brain cancer are more likely to be held back in school

Exercise could ease symptoms for people with chronic lymphocytic leukemia, support and guidance are lacking: Study

Breast cancer surgery: Study finds overnight hospital stay not important for older patients

Cancer Vaccines' Emergence; More Focus on Side Effects; A Nudge for Exercise.

Recommended Articles For You

Understanding Hemosiderosis: Causes, Symptoms, and Treatment Options 

Breast Cancer Secrets: AI-Powered Precision Medicine 

Tumor Evolution Dynamics and Clinical Prognosis 

Uncovering the Hidden Symptoms of Parathyroid Cancer in Women 

Whats more on Hidoc Dr.

Medical Updates
KOL Videos
Surveys
Events

Daily news to keep you up to date

Gain valuable insights with our in-depth KOL Video discussions

Participate and win cash vouchers

Get updates on the latest events happening around the world
Featured News
Featured Articles
Featured Events
Featured KOL Videos

1.

The Boom in ADHD Coaching Has Few Rules

2.

Cancer patients with HIV have demonstrated safety with immune checkpoint inhibitors.

3.

The FDA approves Enhertu for HER2-positive cancers, regardless of tumor type.

4.

Medicaid expansion tied to smaller declines in early-stage cancer detection

5.

Specialist Referrals Are Critical for Functional High-Risk Multiple Myeloma

1.

Mastering Prostate Cancer Care: CME, Certification, Digital Tools, and Evidence-Based Strategies

2.

Pembrolizumab Plus Lenvatinib in EBV-Associated Advanced Intrahepatic Cholangiocarcinoma: Case Study

3.

Targeting the Tumor Microenvironment: Next-Generation Strategies for Immuno-Oncology Success

4.

Unpacking the Importance of White Blood Cells (WBCs) in the Body 

5.

Essential Updates in Hematology in Daily Practice

1.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

2.

International Cancer Conference

3.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

4.

Asian Symposium on Advancement in Hematology and Oncology

5.

Asian Symposium on Advancement in Hematology and Oncology

1.

Virtual Case Study on Elephantiasis of Lower Limb- An Initiative by Hidoc Dr.

2.

Evidence-Based Oncology

3.

Cost Burden/ Burden of Hospitalization For R/R ALL Patients

4.

Rates of CR/CRi and MRD Negativity in Iontuzumab-Treated Patients

5.

Sickle Cell Disease Explained

Fastest Growing Medical Platform for Doctors

Address :
Hidoc Dr. Inc. | Delaware C Corp | 1309 Coffeen Ave. Suite 1200, Sheridan WY, 82801

Phone :
+1-415-463-3094

Email :
anishagadia@hidoc.co

Quick Links

Drug DatabaseDrug InteractionDiseases Database
KOL VideosKnowledge HubQuizzes
Medical UpdatesEventsAbout Us

© Copyright 2026 Hidoc Dr. Inc.

Terms & Conditions - LLP | Inc. | Privacy Policy - LLP | Inc. | Account Deactivation
Home
Profile
Login
bot