The Evolving Landscape of Sickle Cell Disease Treatment

Published Date: 17 Jun 2026

Gene therapy and small molecules are opening the door to new curative approaches, but access continues to be a barrier for most patients.

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HF Polypill May Improve Drug Adherence, a Pilot Trial Finds

Customizable polypill for patients with heart failure with reduced ejection fraction may improve adherence and lower pill burden, and its use appears feasible and acceptable.

Stroke Survivors Aged 50 or Older See Life Expectancy Gains

Life expectancy at age 50 years has increased in US individuals with a history of stroke.

Statins May Slow Cognitive Decline in Women With AD

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Todays Updates

Palliative Care Remains Uncommon in Young Adults With Cancer

Concurrent palliative care use among young adults with advanced cancer is less than 20%, with substantial variation across cancer types.

Latest News

Extreme heat, humidity, altitude, and travel-related disruptions may challenge 2026 World Cup players’ endurance, recovery, and overall performance.

What patients ‘think’ is important about muscle isn’t usually what will benefit them most — especially if they’re hesitant to strength train.

Customizable polypill for patients with heart failure with reduced ejection fraction may improve adherence and lower pill burden, and its use appears feasible and acceptable.

Life expectancy at age 50 years has increased in US individuals with a history of stroke.

In an observational study, statin use was associated with slower cognitive decline in women with Alzheimer’s disease and elevated low-density lipoprotein cholesterol.

Two experts debated this question at the American Diabetes Association 2026 Scientific Sessions.

News All Time

Doctors’ Handwriting: Why Scribbles Still Matter

From prescription errors to a handwriting-inspired font, experts revisit why physicians’ handwriting continues to raise practical and patient safety concerns.

MHRA Contraindicates Domperidone in Phaeochromocytoma

A European safety review found four reports of severe hypertension linked to domperidone in these patients.

Home ECG Alerts Often Do Not Prompt Follow-up for AF

Older adults with hypertension who received atrial fibrillation alerts from home blood pressure monitors rarely sought medical evaluation, and nearly half with confirmed AF remained undiagnosed a year later.

Hypertension in HCM: What Clinicians Should Know

Concomitant hypertension in patients with hypertrophic cardiomyopathy shows a greater burden of myocardial fibrosis on cardiac imaging and is linked to a higher risk for death.

Can High-Protein Pregnancy Diet Affect Child Lipid Profile?

A high-protein and low-glycaemic index diet during pregnancy can negatively affect lipid profile in children through 9 years of age.

Thyroid Issues Can Worsen Prognosis of Heart Failure

Thyroid dysfunction is associated with a higher risk for long-term mortality in patients with heart failure with mildly reduced ejection fraction.

Penile Enlargement Surgery: Can Size Improvements Last?

Researchers evaluate an autologous reconstructive approach designed to improve penile girth and flaccid length while avoiding synthetic implants and repeat procedures.

Tenecteplase Speeds Acute Ischemic Stroke Care

Registry data show that tenecteplase shortens door-to-needle and door-in-door-out times compared with alteplase in patients with acute ischemic stroke.

Adults Aged 75 or Older With MASLD Face Polypharmacy Burden

Among older adults with metabolic dysfunction-associated steatotic liver disease, those aged 75 years or older face a notable burden of polypharmacy.

AI Tool Flags Six Acute Abdominal Emergencies on CT

A deep learning system uses multiwindow encoding to classify and map six acute life-threatening abdominal emergencies on CT scans to a clinical nine-region grid.

5 Smarter Ways to Beat Medical Information Overload

Medical evidence continues to grow rapidly, and these five practical strategies help physicians prioritize high-quality research, use AI effectively, and stay current more efficiently.

Grumblings Over CKM Guideline Not Warranted, Experts Say

Experts push back against concerns of overmedicalization and confusing staging with the new AHA/ACC guideline on cardiovascular-kidney-metabolic syndrome.

Eleven New Molecular Targets Expand Treatment Options

Eleven new molecular drug targets receive approval in 2025, expanding treatment options for rare diseases, cancer, and infectious diseases.

How to Prepare Patients for Exotic Travel: 10 Tips for GPs

From pretravel counseling to vaccinations, prophylaxis, and environmental precautions, here is how general practitioners can help travelers reduce risks before and during their trip.

Can Europe Keep Its Medicines Cool in 40 °C+ Summers?

As European heat waves shatter records, aging clinical infrastructure and lack of funding leave lifesaving, temperature-sensitive drugs vulnerable to degradation.

Infections May Raise Long-Term Risk for Chronic Disease

Experts say infections are an underrecognized driver of chronic disease, with inflammation helping fuel cardiovascular, renal, and neurologic risks.

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