Acne scars: new treatment

Published Date: 02 Mar 2023

Acne can ruin a person's life. What is the real evidence for an effective treatment for different types of acne scars?

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S3 Episode 4: Cannabis and Medicinal Mushrooms in Cancer Survivorship

Drs Kathryn J. Ruddy and Stacy D. D'Andre discuss when cannabis, medicinal mushrooms, and psychedelic mushrooms may be useful for treating specific symptoms in patients with cancer.

Aug 08 2025 This Week in Cardiology

Listener feedback on SURPASS CVOT, AF ablation and the limits of meta-analyses, a Watchman alert from FDA, and oral anticoagulation choices in elderly patients are discussed by John Mandola, MD, in this week’s podcast.

Episode 4: A Surgeon's Guide to Hidradenitis Suppurativa

Join surgeon Dr Julie Caffrey as she shares her approach to hidradenitis suppurativa surgery, from patient selection to excision, reconstruction, and reducing recurrence.

Jul 18 2025 This Week in Cardiology

Finerenone, what not to consider when choosing treatment of AS, brain health after atrial fibrillation ablation, early rhythm control for AF, and Watchman reimbursement cuts are discussed by John Mandrola, MD, in this week’s podcast.

May 30 2025 This Week in Cardiology

Listener feedback, CRT vs CSP, important clues on the ECG, beta-blocker interruption after myocardial infarction, novel approaches to LDL-C lowering, and ICD decisions in cardiac sarcoidosis are the topics John Mandrola, MD, discusses in this week’s podcast.

May 23 2025 This Week in Cardiology

Listener feedback on sports “disqualification,” big digoxin news, Brugada syndrome, another positive finerenone study, and unblinded transcatheter trials are discussed by John Mandrola, MD, in this week’s podcast.

Todays Updates

Nalbuphine Extended-Release Reduces Chronic Cough in IPF, with Philip Molyneaux, MBBS Philip Molyneaux, MBBS

New Phase 2 Trial to Test TREM2-Stabilizing Agent VHB937 in Alzheimer Disease Marco Meglio

A phase 2 study at CTAD 2025 explores VHB937's potential in treating early Alzheimer disease, focusing on safety and efficacy in patients.

MRI Analysis Shows Stem Cell Therapy Laromestrocel Reduced Neuroinflammation in Mild Alzheimer Disease Isabella Ciccone, MPH

In an analysis of the phase 2a CLEAR MIND study presented at CTAD 2025, laromestrocel treatment was associated with reduced hippocampal neuroinflammation in patients with mild Alzheimer disease.

Phase 3 Trial to Uncover Therapeutic Potential of 5-HT6 Antagonist Masupirdine to Treat Alzheimer Agitation Louie Pasculli

A new phase 3 clinical trial is underway to evaluate masupirdine, a selective 5-HT6 receptor antagonist, as a potential treatment for agitation in patients with Alzheimer’s disease.

Pulmonary Rehabilitation Reduces Type 2 Inflammation in High Inflammation Asthma

Pulmonary Rehabilitation Reduces Type 2 Inflammation in High Inflammation Asthma

Mental Health Apps Gain High Uptake but Struggle With Adherence, Retention

Mental Health Apps Gain High Uptake but Struggle With Adherence, Retention

6 Ophthalmology Headlines You Missed in October 2025

6 Ophthalmology Headlines You Missed in October 2025

Todays Updates

Nalbuphine Extended-Release Reduces Chronic Cough in IPF, with Philip Molyneaux, MBBS Philip Molyneaux, MBBS

New Phase 2 Trial to Test TREM2-Stabilizing Agent VHB937 in Alzheimer Disease Marco Meglio

A phase 2 study at CTAD 2025 explores VHB937's potential in treating early Alzheimer disease, focusing on safety and efficacy in patients.

MRI Analysis Shows Stem Cell Therapy Laromestrocel Reduced Neuroinflammation in Mild Alzheimer Disease Isabella Ciccone, MPH

In an analysis of the phase 2a CLEAR MIND study presented at CTAD 2025, laromestrocel treatment was associated with reduced hippocampal neuroinflammation in patients with mild Alzheimer disease.

Phase 3 Trial to Uncover Therapeutic Potential of 5-HT6 Antagonist Masupirdine to Treat Alzheimer Agitation Louie Pasculli

A new phase 3 clinical trial is underway to evaluate masupirdine, a selective 5-HT6 receptor antagonist, as a potential treatment for agitation in patients with Alzheimer’s disease.

Pulmonary Rehabilitation Reduces Type 2 Inflammation in High Inflammation Asthma

Pulmonary Rehabilitation Reduces Type 2 Inflammation in High Inflammation Asthma

Mental Health Apps Gain High Uptake but Struggle With Adherence, Retention

Mental Health Apps Gain High Uptake but Struggle With Adherence, Retention

6 Ophthalmology Headlines You Missed in October 2025

6 Ophthalmology Headlines You Missed in October 2025

Latest News

Drs Kathryn J. Ruddy and Stacy D. D'Andre discuss when cannabis, medicinal mushrooms, and psychedelic mushrooms may be useful for treating specific symptoms in patients with cancer.

Listener feedback on SURPASS CVOT, AF ablation and the limits of meta-analyses, a Watchman alert from FDA, and oral anticoagulation choices in elderly patients are discussed by John Mandola, MD, in this week’s podcast.

Join surgeon Dr Julie Caffrey as she shares her approach to hidradenitis suppurativa surgery, from patient selection to excision, reconstruction, and reducing recurrence.

Finerenone, what not to consider when choosing treatment of AS, brain health after atrial fibrillation ablation, early rhythm control for AF, and Watchman reimbursement cuts are discussed by John Mandrola, MD, in this week’s podcast.

Listener feedback, CRT vs CSP, important clues on the ECG, beta-blocker interruption after myocardial infarction, novel approaches to LDL-C lowering, and ICD decisions in cardiac sarcoidosis are the topics John Mandrola, MD, discusses in this week’s podcast.

Listener feedback on sports “disqualification,” big digoxin news, Brugada syndrome, another positive finerenone study, and unblinded transcatheter trials are discussed by John Mandrola, MD, in this week’s podcast.

News All Time

The Dual Role of Illusion in Patient Care

From painted leaves to placebos, we must balance hope and honesty

The Global Applicability of the DanGer Shock Trial

Positive results were shown for implantation of a mechanical circulatory support device plus standard care for patients presenting with cardiogenic shock and STEMI.

Surprising Mediator Links Poverty and Knee Pain

Study: It's not deprivation per se, but intervening factors that go with it

Sodium Channel Blocker Relieves Acute Pain in Phase III Data

Trials favor a first new class of pain drug in years

No X-Ray Proof of Rare Surgical Complication Tied to GLP-1 Agonists

Conundrum of holding meds continues following conflicting reports of aspiration events

Deep Neuromuscular Blockade Helps Keyhole Surgery, but Not Outcomes Per Se

No impact on safety outcomes after laparoscopic surgery

Stable Angina: A Patient-Centered Approach

A review of the complementary role of coronary revascularization, optimal medical therapy, and lifestyle interventions in the management of stable angina, and the importance of an approach that targets the pathobiology.

Food Retention Risk Low for GLP-1 Users When Endoscopy Is Combined With Colonoscopy

Bowel preparation protocols appeared protective in small study

Sep 27 2024 This Week in Cardiology

Surgical clearance, NICM assessment, dueling perspectives on PCI as first-line therapy for angina, GDMT in HFrEF are the topics John Mandrola, MD, discusses in this week?s podcast.

S2 Episode 5: The Complex Patient With Pulmonary Hypertension and ILD

Drs Jeffrey Swigris and M. Patricia George discuss the complexities of diagnosing and treating pulmonary hypertension in patients with interstitial lung disease.

Laboratory and Radiologic Tests When Assessing a Patient With HF

Dr Kittleson uses the universal heart failure definition to assess symptoms, relying on echocardiograms and natriuretic peptides for diagnosis and classification.

Sep 13 2024 This Week in Cardiology

More from ESC: the SCOFF trial and fasting before cardiac cath, MATTERHORN, humbling data with AI, plus a reflection on the work of being a patient are the topics John Mandrola, MD, covers this week.

Impact of Lp(a) on LDL-C or Apo-B-related Risk of CAD

A comparison of the association between LDL-C and LDL-C corrected for Lp(a)-C (LDLLp(a)corr) with incident coronary heart disease.

Inducing General Anesthesia From the Doctor's Point of View

Watch from the perspective of an anesthesiologist as he prepares a patient to go under the knife

What the Matthew Perry Tragedy Reminds Us About Ketamine Use

We must develop multi-disciplinary safety standards for ketamine clinics

HDL Parameters and Risk of Heart Failure

The association between HDL particle concentration and size with heart failure is studied in participants from the ARIC, MESA, PREVEND, and Dallas Heart studies.

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