Exercise Plus Diet Lowers Leptin in Hypertensive Obesity

Published Date: 23 May 2026

A 16-week supervised aerobic exercise program combined with a hypocaloric diet reduces leptin levels in adults with hypertension and overweight or obesity.

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One in Four Teen Girls and Young Women at Risk for PMOS

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Palopegteriparatide Benefits Sustained Beyond 3 Years

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HIV Care Coordination Program May Reduce Deaths in NYC

New York City’s revised Care Coordination Program may help reduce risks for all-cause and HIV-related deaths among people with HIV infection, including those at the highest risk for poor outcomes.

Teplizumab Approved for Pediatric Stage 3 Type 1 Diabetes

The drug was previously approved for stage 2 T1D.

One in Four Teen Girls and Young Women at Risk for PMOS

Findings suggest young females should be assessed and, if at risk, monitored.

Palopegteriparatide Benefits Sustained Beyond 3 Years

Final results from the PaTHway trial show the long-acting parathyroid hormone therapy enabled patients with hypoparathyroidism to achieve independence from high-dose calcium and vitamin D supplements.

Testosterone Prescribing Often Ignores Guidelines

Only 12% of patients prescribed testosterone underwent appropriate diagnostic testing, and overprescribing was common in a single-center US study.

Encaleret Shows Rapid Response in ADH1

The oral modulator of the calcium-sensing receptor targets the causes of ADH1, significantly improving serum and urine calcium levels.

Off-Label Rxs: Thinking Out of the Box for Skin Diseases

Off-label alternatives for FDA-approved therapies can be as effective, cheaper, and in some cases safer despite never having been submitted for regulatory approval.

Latest News

Migraine with aura is associated with an increased risk for ischemic stroke in middle-aged and older adults, particularly men younger than 72 years, a new study shows.

The MHRA has approved the UK's first oral semaglutide tablet for obesity, with NHS availability pending a NICE evaluation.

Patients place high value on listening, trust, and clear communication, which are factors that shape adherence, satisfaction, and the overall experience of care.

GLP-1 medications may not directly cause oral health problems, but their mechanisms can. Take a cue from dental experts for insights on how to manage these oral effects.

Despite early termination, the ANTHEM-HFrEF trial holds important lessons for investigators.

The risk for extrahepatic cancers varies among subgroups of steatotic liver disease, with the highest risk seen in patients with metabolic dysfunction and alcohol-associated liver disease.

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Heat-Related CVD Burden May Nearly Triple by 2050

Rising temperatures are projected to nearly triple the burden of cardiovascular disease in the US by 2050 under a scenario of high emissions of greenhouse gases, a study estimates.

Stroke Treatment Outcomes Vary by Cancer Subtype

Patients with cancer who suffer an acute ischaemic stroke face higher odds of in-hospital death and bleeding after recanalisation therapy, with outcomes varying by cancer subtypes.

Lung Ultrasound Plus CRP May Guide Antibiotic Decisions

Lung ultrasound may help identify a bacterial component in children with acute lower respiratory tract infections and may guide antibiotic decisions when paired with C-reactive protein.

Serum Potassium Concentrations Shape Heart Failure Risk

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Semaglutide Accepted in Scotland for CV Risk Reduction

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ACC/AHA Release First-Ever Guideline for CKM Syndrome

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Could the Iran Conflict Disrupt MRI Services?

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Common Metabolic Issue in Women Tied to Mortality Risk

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Rivaroxaban Flops for Prevention in Advanced CKD

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Advance Directives May Reduce Unnecessary End-of-Life Care

Older adults close to death often receive unnecessary end-of-life medical treatments in hospitals.

Obesity Stigma: Is Art History the Fix?

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Retatrutide Data Show Dramatic Weight Loss, Other Benefits

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Digoxin Shows Signs of a Heart Failure Revival

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FDA Neurology Roundup: May 2026

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