Flu season ends with a whisper, not a bang.

Published Date: 14 Mar 2023

The 2022-2023 flu season is on the edge of life which has been predicted for half of January and most of February.

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Painful Stump Ischemia in a Man After Amputation

A man with a prior below-knee amputation develops progressive stump pain, and vascular imaging reveals an unexpected arterial blockage that is still treatable.

Before Automating Healthcare, Define What to Automate

What belongs to medicine, and what belongs to the machine? Dr Travis Bias argues that AI must augment — not replace — human connection in clinical care.

Improving GAD Screening: What the GAD-7 May Miss

Dr Lily Brown explains why GAD is often underdiagnosed and how overreliance on depression labels and the GAD-7 alone can miss key anxiety disorders.

Ask About Her Job: Medicine’s Missing Question

Dr Raghda Rashad argues that screening for occupational history could keep more women in the workforce, but most clinicians never ask.

Extreme Heat: Is Health Toll Worse Than We Think?

Extreme heat is already increasing deaths, worsening chronic diseases, and widening health inequalities, as clinicians face growing pressure to prepare for a hotter future.

Clinical Connections May Tie Headaches and Obesity Together

Patients may not know it, but obesity can lead to more headaches.

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Real-World EV Plus Pembro Success Seen in Urothelial Cancer

A retrospective study evaluates outcomes associated with first-line enfortumab vedotin plus pembrolizumab vs gemcitabine plus cisplatin in patients with metastatic urothelial carcinoma.

Germline Variants Predict Lobular Breast Cancer Recurrence

For women with invasive lobular carcinoma, pathogenic variants in breast cancer risk genes predict high odds of early recurrence.

MRI Enhancement Predicts Breast Cancer in BRCA Carriers

Higher background parenchymal enhancement on breast MRI may signal greater risk among women who carry BRCA mutations.

Polatuzumab Vedotin Boosts Survival in Relapsed DLBCL

Patients with relapsed or refractory diffuse large B-cell lymphoma, who were ineligible for autologous stem cell transplant, were randomly assigned to receive Pola-R-GemOx or R-GemOx.

Todays Updates

Real-World EV Plus Pembro Success Seen in Urothelial Cancer

A retrospective study evaluates outcomes associated with first-line enfortumab vedotin plus pembrolizumab vs gemcitabine plus cisplatin in patients with metastatic urothelial carcinoma.

Germline Variants Predict Lobular Breast Cancer Recurrence

For women with invasive lobular carcinoma, pathogenic variants in breast cancer risk genes predict high odds of early recurrence.

MRI Enhancement Predicts Breast Cancer in BRCA Carriers

Higher background parenchymal enhancement on breast MRI may signal greater risk among women who carry BRCA mutations.

Polatuzumab Vedotin Boosts Survival in Relapsed DLBCL

Patients with relapsed or refractory diffuse large B-cell lymphoma, who were ineligible for autologous stem cell transplant, were randomly assigned to receive Pola-R-GemOx or R-GemOx.

Latest News

A man with a prior below-knee amputation develops progressive stump pain, and vascular imaging reveals an unexpected arterial blockage that is still treatable.

What belongs to medicine, and what belongs to the machine? Dr Travis Bias argues that AI must augment — not replace — human connection in clinical care.

Dr Lily Brown explains why GAD is often underdiagnosed and how overreliance on depression labels and the GAD-7 alone can miss key anxiety disorders.

Dr Raghda Rashad argues that screening for occupational history could keep more women in the workforce, but most clinicians never ask.

Extreme heat is already increasing deaths, worsening chronic diseases, and widening health inequalities, as clinicians face growing pressure to prepare for a hotter future.

Patients may not know it, but obesity can lead to more headaches.

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Deep Brain Stimulation: Can Remote Follow-Up Expand Access?

Remote programming allows clinicians to adjust deep brain stimulation from a distance, improving access to specialist follow-up while reducing routine clinic visits.

Rheumatologist Shortage to Hit Nonmetropolitan Areas Hardest

Workforce projections show an uneven distribution of rheumatologists in the US, with notable shortages in nonmetropolitan areas and certain states and districts.

Epcoritamab Shows Promise in Frail Older Adults With LBCL

A phase 2 trial assesses fixed-duration epcoritamab monotherapy as first-line therapy for frail older adults with newly diagnosed anthracycline-ineligible large B-cell lymphoma.

US Nuclear Power Regulator Proposes Changing Rule Protecting People From Radiation

The U.S. nuclear power regulator on Wednesday proposed changes to a rule protecting people from radiation, the latest proposal pushed by the Trump administration to change...

A Man With a Recurrent Scalp Tumor

A recurrent scalp mass initially diagnosed as a pilomatrixoma is ultimately found to be a rare adnexal malignancy, underscoring the need for histologic precision.

AI-Generated Presentations: Can Better Prompts Save Time?

Structured prompts help physicians prepare conference presentations faster, but expert review remains essential to verify evidence, references, and scientific accuracy.

Higher Daytime Light Exposure Linked to Lower Dementia Risk

Exposure to relatively bright daytime light is linked to lower dementia risk and may provide a novel, measurable method to identify individuals at high risk for dementia.

Prior Stillbirth May Up Risk for Subsequent Stillbirth

Individuals with a prior stillbirth have more than double the risk for stillbirth in their next pregnancy, with the risk increasing sixfold when the initial loss is due to placental insufficiency.

AI May Help Predict Liver Cancer Risk in Young Adults

A machine learning algorithm predicts early-onset liver cancer in young adults better than traditional models.

What Accountants Want Docs to Do NOW Before 2027 Taxes

Physicians can make smart decisions now to maximize their income and lower their tax burden for next year with these pro tips from accountants.

Brazil’s Malaria Pioneer Leads WHO Tropical Disease Program

The physician who spent 26 years fighting malaria in the Amazon is now directing WHO’s tropical disease program — and has a clear-eyed view of the threats ahead.

PsA Rx Pipeline and Practice: What Clinicians Need to Know

Dr Alexis Ogdie walks through advanced PsA drug classes, and spotlights emerging agents changing the treatment map.

Cancer Disparities Report: Promising Trends, Persistent Gaps

A biennial report from the American Association for Cancer Research cites progress in narrowing US cancer disparities, as well as ongoing challenges.

When Does Online Behavior Tip Into Addiction?

Experts call for standardized diagnostic criteria, stronger clinical evidence, and public health measures to improve the recognition and management of problematic use of the internet.

PARP Discontinuation Maintains Outcomes in Ovarian Cancer

New data show durable progression-free survival among exceptional responders to PARP inhibitors after discontinuation, though selection bias limits causal interpretation.

Experts on Chemsex: Can Integrated Care Make a Difference?

Experts call for integrated sexual health, harm reduction, and mental health services to improve care of individuals engaging in chemsex.

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