FDA Warns of Fatal Liver Injuries Tied to Drug It Wants Pulled From Market

Published Date: 11 May 2026

Eight deaths and dozens of DILI cases linked to avacopan for ANCA-associated vasculitis

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Todays Updates

Sevabertinib Approved for First-Line Mutated NSCLC

The oral HER2 TKI was previously given accelerated approval in the second line for the indication.

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U.S. Health Secretary Robert F. Kennedy Jr acknowledged on Friday that measles caused the recent death of an infant in Pennsylvania, citing information from a county...

Aircrew may be more likely to die from cancers potentially linked to radiation, but can that be attributed to cosmic radiation — and what, if anything, should physicians do differently?

Viral discussions about sun protection, vitamin D, and oral collagen often outpace the evidence, leaving clinicians to weigh the benefits, limitations, and patient concerns.

AI-assisted coherence tomography shows feasibility as a method of detecting basal cell carcinomas when they are still undetectable, but clinical relevance is still being evaluated.

A genetic analysis suggests that increased GLP1R expression is linked to higher risk for male pattern hair loss.

Teens who follow beauty influencers and watch skincare tutorials use far more personal care products, raising concerns over chemical exposure.

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Diclofenac Did Not Reduce Chemo-Induced Hand-Foot Syndrome

Researchers assess hand-foot syndrome in patients receiving diclofenac who are scheduled to receive capecitabine-based chemotherapy for cancer.

Upadacitinib Effective in PsA After TNF Inhibitor Failure

Upadacitinib is linked to effective clinical responses in patients with psoriatic arthritis who have received prior TNF inhibitor therapy.

Does Tapering TNF Inhibitors Maintain Low Disease Activity?

In patients with psoriatic arthritis and axial spondyloarthritis, a treat-to-target tapering strategy for TNF inhibitors may maintain low disease activity for up to 2 years.

FDA Approves First Oral Drug for Dermatomyositis in Adults

The FDA has approved brepocitinib (Lisraya), an oral JAK inhibitor, for the treatment of dermatomyositis, a rare autoimmune disease, in adults.

Early Step-Down Safe, Cost-Effective in Stable Candidiasis

Switching from an echinocandin to an azole within 5 days is not associated with worse outcomes in clinically stable adults with invasive candidiasis, a study shows.

How Safe Is Lifileucel After Patients Go Home?

The T-cell therapy’s inpatient toxicity is well-characterized, but the risks patients may face after hospital discharge have been unclear.

China Approves J&J Psoriasis Pill Icotyde, Says Drugmaker

China's drug regulator has approved Johnson & Johnson's oral pill ⁠for psoriasis, the company said on Thursday, intensifying competition in the ⁠world's second-largest...

Vulvar Lichen Sclerosus Affects 1 in 700 US Women

Vulvar lichen sclerosus shows markedly higher rates in women over 60, with White women experiencing the highest burden, a study shows.

Brepocitinib Controls Skin Disease in Dermatomyositis

Brepocitinib produces rapid and sustained improvements in skin disease, itch, and skin-related quality of life in adults with dermatomyositis.

ctDNA Detects Postsurgical Merkel Cell Recurrence

Circulating tumor DNA surveillance detects Merkel cell carcinoma recurrence after curative-intent surgery.

Biologic Choice May Affect PsA Progression in Psoriasis

In patients with psoriasis, interleukin-targeting inhibitors are associated with a lower risk for psoriatic arthritis than TNF inhibitors, a long-term real-world study finds.

Longer Targeted Therapy May Not Raise Cancer Risk in SpA

Using targeted therapy for spondyloarthritis for more than 6 months per year is not associated with an increased risk for cancer compared with using targeted therapy for shorter durations.

Ruxolitinib Improves Vitiligo Outcomes in Real-World Study

Topical ruxolitinib shows sustained repigmentation through 52 weeks with improvements in anxiety and depression in patients with non-segmental vitiligo.

Data Gaps Hinder Response to Climate-Driven Infections

Climate change is reshaping infectious disease risk in Italy and beyond, highlighting the need for better diagnostics, integrated data, and stronger global cooperation.

Clinical Crosstalk: Integrating ICIs and Strengthening Collaborative Care in NMSC

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