Sozinibercept for Wet AMD Misses Primary Endpoint in Phase 3 COAST Trial

Published Date: 11 Apr 2025

The pivotal trial investigating sozinibercept combination therapy failed to meet the primary endpoint of mean change in BCVA at 52 weeks.

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A treatment that targets dysfunctional photoreceptors regardless of the underlying genetic mutation leads to improved functional vision in advanced severe vision loss.

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Navigating Sustained Delivery in DME: An Interactive Clinical Decision-Making Simulation

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One GLP-1 Drug May Be Better Than Rivals for Glaucoma Risk

But it's not time to prescribe tirzepatide outside current indications, expert says

Color Blindness and Bladder Cancer: A Bad Combination for Survival?

Study suggests inability to identify blood in urine may delay diagnosis and reduce survival

Cardiovascular Risk Score Shows Value in Predicting Future Eye Disease

The score is commonly calculated in primary care

People, Faces Appeared Smaller Than Usual in Patient's Rare Case

63-year-old had an atypical cause of Alice in Wonderland Syndrome

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FDA OKs More Eye Drops That Can Replace Reading Glasses

Once-daily carbachol/brimonidine tartrate significantly improves aging-related vision loss

Sleeping With Two Pillows May Raise Internal Eye Pressure in Glaucoma

Stacked pillows alter the neck position and may compress the jugular, researchers suggest

Teen Boy Grows a Tooth Between Eyelid and Eyebrow

The 16-year-old underwent surgery to remove an ectopic canine tooth in left eye's superior orbit

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Earlier concerns about surgery accelerating AMD progression likely overstated, researcher says

Hospital Had Ties to Epstein; Naked Knifeman at Eye Doctor; Health Department Probed

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Some Blind Fans to Experience Super Bowl With Tactile Device That Tracks Ball

About 10 blind and low-vision fans will have an opportunity to use the technology

CDC Study Warns of Vision-Threatening Eye Infections After Laser Surgery

Three patients at New York City clinic developed fungal keratitis caused by a mold

Dry Eye: Handmaiden to Many Autoimmune Conditions, Not Just Sjogren's Disease

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Retinopathy Risk With Long-Term HCQ Treatment Detailed in Meta-Analysis

Eye damage remains uncommon after 15 years, but certain factors increase the risk

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First evidence of formulation-specific difference, significantly higher in men than women

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