'Virtual clinical trials' may predict success of heart failure drugs

Published Date: 17 Sep 2025

Mayo Clinic researchers have developed a new way to predict whether existing drugs could be repurposed to treat heart failure, one of the world's most pressing health challenges. By combining advanced computer modeling with ...

Read Full News

Latest News

Docs Face Confusing Rules for Medicaid Work Mandate Waivers

As new Medicaid work mandates start to take effect, patients in some states are asking physicians for waivers, saying they’re too sick or disabled to work. But rules for granting waivers are confusing.

Unindicated GLP-1 Prescriptions Climb Since 2021 in the US

More than 6 million Americans started GLP-1 drugs since 2021 — and a growing share had no documented medical reason for taking them.

Heart Issues Leading Cause of Pregnancy-Related Death

Deaths from infection or sepsis increased from 2018 to 2021 but decreased in the following years.

Inflammatory Hypothesis Proponents Undaunted by ZEUS Flop

Failure of an anti-inflammatory monoclonal antibody in the randomized trial shouldn’t be seen as negating the role of inflammation in atherosclerotic cardiovascular disease, some experts argued.

Deep Dive: Statins in 2026: New Guideline, New Safety Data

A new ACC/AHA guideline restores numeric LDL-C targets while a 150,000-patient CTT reassessment clears most label-listed statin side effects.

Migraine Tied to Earlier Stroke, Better Recovery

Migraine is linked to an earlier onset of stroke, yet young patients with stroke and a history of migraine experience better functional recovery at discharge.

Todays Updates

Hyponatremia Risk Varies Among Second-Gen Antipsychotics

Aripiprazole is associated with a lower risk for hyponatremia compared with olanzapine in patients treated with second-generation antipsychotics, a new cohort study shows.

HCT Survival Outcomes Improving in Relapsed Hodgkin Lymphoma

Researchers evaluate changes in post-transplantation outcomes among patients with relapsed or refractory Hodgkin lymphoma from 2010 to 2022.

How Much of a Cancer Drug Is Too Much?

In a recent KFF survey, 43% of US adults said they had skipped their medication in the past year because of cost.

Todays Updates

Hyponatremia Risk Varies Among Second-Gen Antipsychotics

Aripiprazole is associated with a lower risk for hyponatremia compared with olanzapine in patients treated with second-generation antipsychotics, a new cohort study shows.

HCT Survival Outcomes Improving in Relapsed Hodgkin Lymphoma

Researchers evaluate changes in post-transplantation outcomes among patients with relapsed or refractory Hodgkin lymphoma from 2010 to 2022.

How Much of a Cancer Drug Is Too Much?

In a recent KFF survey, 43% of US adults said they had skipped their medication in the past year because of cost.

Latest News

As new Medicaid work mandates start to take effect, patients in some states are asking physicians for waivers, saying they’re too sick or disabled to work. But rules for granting waivers are confusing.

More than 6 million Americans started GLP-1 drugs since 2021 — and a growing share had no documented medical reason for taking them.

Deaths from infection or sepsis increased from 2018 to 2021 but decreased in the following years.

Failure of an anti-inflammatory monoclonal antibody in the randomized trial shouldn’t be seen as negating the role of inflammation in atherosclerotic cardiovascular disease, some experts argued.

A new ACC/AHA guideline restores numeric LDL-C targets while a 150,000-patient CTT reassessment clears most label-listed statin side effects.

Migraine is linked to an earlier onset of stroke, yet young patients with stroke and a history of migraine experience better functional recovery at discharge.

News All Time

Pachychoroid Disease Progression Remains Low

Most eyes with pachychoroid features maintained their subtype over 2 years, with progression to pachychoroid neovasculopathy developing in only a small fraction of eyes.

Obesity Class III Linked to Death Risk in Younger Adults

Younger adults with severe obesity face significantly increased risk for mortality, while older adults show minimal differences across obesity classes.

Integrase Inhibitors Safe for Heart in HIV Patients

A Swiss study tracking thousands of people with HIV found no long-term cardiovascular penalty when switching to integrase inhibitor-based therapy, though a small early-year uptick in events warrants clinical attention.

Mild Tremor Tied to Cognitive Decline in Seniors

Even subtle hand tremor in older adults may signal more than just a benign motor quirk — new population data reveal an unexpected cognitive connection.

Cefadroxil Effective for Gram-Positive Bacteremia

Oral cefadroxil shows comparable outcomes to intravenous and alternative oral regimens in treating gram-positive bloodstream infections, a recent study shows.

Dapagliflozin Reduces AKI After Cardiac Surgery

Four doses of the SGLT2 inhibitor dapagliflozin reduce acute kidney injury risk after elective cardiac surgery, with a low incidence of ketoacidosis.

Dexrazoxane May Preserve LV Function in Cancer Survivors

Researchers analyzed echocardiographic data from patients who received dexrazoxane before doxorubicin as part of their treatment for cancer in childhood.

Photon-Counting CT Boosts Stent Fracture Detection

A phantom study shows that photon-counting detector CT significantly improves the detection of visceral endovascular stent fractures compared with conventional CT.

Postpartum Health Coaching Boosts Blood Pressure Control

Health coaching may help close a critical gap in care after a hypertensive pregnancy.

Five Steps to Earlier Heart Failure Detection

Heart failure often hides behind vague complaints. These five primary care steps can help spot it earlier and guide faster, evidence-based treatment.

How to Talk About Exercise When Weight Loss Is Off the Table

In the era of GLP-1 drugs, weight loss is no longer a compelling pitch. Here’s how to reframe physical activity for patients.

Central Adiposity May Reclassify CVD Risk Beyond BMI

Among individuals with normal BMI, elevated waist circumference or waist-to-hip ratio may identify cardiovascular risk beyond BMI.

Allopurinol Offers No Heart Benefit in Kidney Donors

The use of allopurinol leads to significantly lower uric acid levels but shows no effect on heart mass, blood pressure, or insulin sensitivity in healthy living kidney donors, a phase 2b trial finds.

Cardiometabolic Index Can Predict Mortality Risk in T2D

A higher cardiometabolic index is linked to an increased risk for all-cause and cardiovascular mortality in patients with T2D, serving as an effective prognostic tool.

Quarter of Gestational Diabetes Moms Get Early Hypertension

More than 1 in 4 women with recent gestational diabetes developed hypertension at 5 months postpartum, driven primarily by baseline maternal characteristics rather than pregnancy complications.

Retatrutide Trims Weight and A1c in Diabetes

Retatrutide helped patients lose up to 30% of body weight in new trials, among the largest effects yet from a weight-loss drug – but a new safety signal raises questions.

Recommended News For You

FDA Leaders Explain Their Choice Regarding Cancer Risk Warning in CAR-T Investigation.

Clinical trial is testing whether heavy lifting could combat cancer side effects

Experts Discuss Groundbreaking Advances in EGFR-Mutant Lung Cancer

A healthier lifestyle after bowel screening shown to prevent bowel cancer

Survival improved with lobectomy, segmentectomy in early non-small cell lung cancer

Imetelstat for MDS-relateret anemia er godkendt af Food and Drug Administrations panel.

Personalized Breast Cancer Treatment; Insights Into HPV in Men; Exercise and Cancer

Recommended Articles For You

Symptoms and Causes of Phlegmasia Cerulea Dolens: A Comprehensive Guide  

Unleashing the Inner Predator: Reprogramming Macrophages to Conquer Cancer Immunotherapy 

Revolutionizing Cancer Treatment with Trilaciclib: How a New Drug is Transforming Outcomes 

The Essential Roadmap for Nutritional Excellence in Head and Neck Cancer Care 

Whats more on Hidoc Dr.

Medical Updates
KOL Videos
Surveys
Events

Daily news to keep you up to date

Gain valuable insights with our in-depth KOL Video discussions

Participate and win cash vouchers

Get updates on the latest events happening around the world
Featured News
Featured Articles
Featured Events
Featured KOL Videos

1.

More Americans Are Surviving Cancer. But the Mental Health Challenges Can Persist.

2.

Glioma Outcomes Shaped by Subtype More Than Tx Sequence

3.

We Don't Always Know What's 'Best' for Our Patients

4.

Should the UK introduce targeted prostate cancer screening? The case for and against

5.

Germline Profiling May Improve Risk Stratification in t-MNs

1.

Cancer Immunotherapy: Advances, Guidelines, and Practical Tools for Modern Oncology Practice

2.

Vaccines that can help prevent cancer

3.

HPV-Related Cervical Cancer: Advances in Screening, Preventiofn & Treatment

4.

Liquid Biopsy in Hematologic Malignancies: Current Evidence and Clinical Applications

5.

Advancements in Breast Cancer Treatment: From Chemotherapy to Immunotherapy

1.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

2.

International Cancer Conference

3.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

4.

Asian Symposium on Advancement in Hematology and Oncology

5.

Asian Symposium on Advancement in Hematology and Oncology

1.

Untangling The Best Treatment Approaches For ALK Positive Lung Cancer - Part VI

2.

Rates of CR/CRi and MRD Negativity in Iontuzumab-Treated Patients

3.

Targeting Oncologic Drivers with Dacomitinib: A New Approach to Lung Cancer Treatment

4.

An In-Depth Look At The Signs And Symptoms Of Lymphoma- The Conclusion

5.

Case-Based Learning: Oncology

Fastest Growing Medical Platform for Doctors

Address :
Hidoc Dr. Inc. | Delaware C Corp | 1309 Coffeen Ave. Suite 1200, Sheridan WY, 82801

Phone :
+1-415-463-3094

Email :
anishagadia@hidoc.co

Quick Links

Drug DatabaseDrug InteractionDiseases Database
KOL VideosKnowledge HubQuizzes
Medical UpdatesEventsAbout Us

© Copyright 2026 Hidoc Dr. Inc.

Terms & Conditions - LLP | Inc. | Privacy Policy - LLP | Inc. | Account Deactivation
Home
Profile
Login
bot