Methotrexate beneficial for reducing pain, stiffness in knee osteoarthritis

Published Date: 07 Aug 2024

For patients with knee osteoarthritis (KOA), methotrexate added to usual medication is associated with a significant reduction in pain and improvement in stiffness and function at six months, according to a study published ...

Read Full News

Latest News

HTTP error: 503HTTP error: 503HTTP error: 503HTTP error: 503

Experts Debate Combination Therapy for Pulmonary Fibrosis

Respiratory experts disagree over initiating upfront dual therapy vs sequential escalation as next-generation antifibrotics emerge for pulmonary fibrosis.

Keto Diet Boosts Liver Health More Than Others in Obesity

A ketogenic diet paired with weight loss improves liver health more than a Mediterranean or very low-fat diet with similar weight loss in people with metabolically unhealthy obesity.

Todays Updates

Trappsol Cyclo Misses Primary End Point in Phase 3 Trial for Niemann-Pick Disease Type C Isabella Ciccone, MPH

Findings from the phase 3 TransportNPC study showed that Trappsol Cyclo missed the primary end point in Niemann-Pick type C, but subgroup and survival data support planned 2026 NDA.

NeurologyLive® Friday 5 — October 2, 2026 Isabella Ciccone, MPH

Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending October 2, 2026.

Todays Updates

Trappsol Cyclo Misses Primary End Point in Phase 3 Trial for Niemann-Pick Disease Type C Isabella Ciccone, MPH

Findings from the phase 3 TransportNPC study showed that Trappsol Cyclo missed the primary end point in Niemann-Pick type C, but subgroup and survival data support planned 2026 NDA.

NeurologyLive® Friday 5 — October 2, 2026 Isabella Ciccone, MPH

Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending October 2, 2026.

Latest News

Gelles discussed AI tools that are becoming a part of clinician’s armamentariums and the impact they are having on the field.

Hoang discussed the CARD initiative started at Wayne State University in Detroit that she presented at the ACP IM 2025 meeting.

FDA Commissioner Marty Makary Resigns, Kyle Diamantas Steps In as Acting Head

Nearly 3 in 10 Italians older than 65 years take more than 10 medications, highlighting why deprescribing is gaining attention as a strategy to improve care.

Respiratory experts disagree over initiating upfront dual therapy vs sequential escalation as next-generation antifibrotics emerge for pulmonary fibrosis.

A ketogenic diet paired with weight loss improves liver health more than a Mediterranean or very low-fat diet with similar weight loss in people with metabolically unhealthy obesity.

News All Time

Three-Step Triage May Speed Assessment of Rheumatic Diseases

A three-step triage system may help reduce wait times for patients with inflammatory rheumatic and musculoskeletal disease, although it may still miss some diagnoses.

Breaking the Lab Habit: Rethinking Daily Hospital Testing

Not every patient needs routine daily testing. Breaking the habit can save money and improve patient health. But some habits are hard to break.

Cold Water Is Sufficient for Medical Handwashing

For healthcare handwashing, colder water appears just as effective as warm water, while also lowering resource use and Legionella risk.

Rheumatologists Seek Changes to Looming Medicaid Work Rules

Groups such as the ACR object to a CMS ‘frailty-exemption’ rule intended to make clinicians try to judge patients’ ability to work, noting among their objections a lack of adequate tools for this task.

Can Sexual Experience Reshape the Brain?

New research is exploring whether sexual experience may shape brain circuits linked to reward, learning, and mood — but the human evidence remains early.

Somatic Mutations Shape Systemic Autoinflammatory Disease

Acquired somatic variants may drive over 20% of systemic autoinflammatory disease diagnoses, with VEXAS syndrome and cryopyrin-associated periodic syndromes representing the majority of cases.

Sonographer Shortage Is Affecting Expectant Women’s Health

A sonographer shortage confronts expectant women in Ontario with long commutes for routine ultrasounds.

How Clinicians Can Improve STI Conversations

A Spanish sexologist says the key to better STI detection may be simpler than it seems: create a safe, nonjudgmental space and ask directly.

Ultrasound Expands Options for Chest Lesion Biopsy

A radiation-sparing procedure shows a safe and effective diagnostic potential.

Irish Health Service Operator Fined for Storing Data in Disused Bathroom, Turf Shed

Ireland's health service operator was fined a record amount for an Irish public body by the country's data regulator ⁠for storing medical records in "profound disarray" in...

How to Differentiate the Major Subtypes of ILD

The definitions of interstitial lung disease subtypes have undergone major revisions, encompassing clinical, radiologic, and histologic findings, as well as a few new categories.

Long-Term Primary Care Saves Lives — and Is Hard to Achieve

New research quantifies the benefits of long-term patient relationships. How can you build them in a system that prioritizes high-volume access?

Size Matters for Chest Tubes

New data show similar outcomes with large-bore and small-bore chest tubes in patients with pneumothoraces.

UnitedHealthcare to Drop Prior Authorization Requirements for Range Of Conditions From Oct. 1

UnitedHealth's insurance unit said on Tuesday that a broad range of conditions will no ⁠longer need prior approval, effective October 1, as it aims to eliminate prior...

Rilzabrutinib May Be Promising in IgG4-Related Disease

Rilzabrutinib treatment is associated with a reduction in disease activity in patients with IgG4-related disease and enables most patients to discontinue glucocorticoids without experiencing flares.

What to Know About ‘Musculoskeletal Syndrome of Menopause’

Is new joint pain in perimenopause simple arthralgia or underlying inflammatory arthritis? Learn key diagnostic steps, seronegative RA risks, and hormone replacement therapy insights.

Recommended News For You

In Sickle Cell Disease, Lovo-Cel is "Life-Changing, Transformative.".

Immunotherapy Remains Little Used in Head and Neck Cancer

In cancer patients taking immune checkpoint inhibitors, systematic vitamin D supplementation improves outcomes.

New Gene Therapy Nears EU Nod for Bladder Cancer

An Examine More Into the Acceptance of CRISPR/Cas9 Gene Therapy for Sickle Cell Illness.

Radiotherapy after mastectomy can be avoided, study finds

Low-Dose Radiation Provides Almost Perfect Control Over Slow-Growing Lymphoma.

Recommended Articles For You

Unlocking the Secrets of Improved Ovarian Cancer Survival Rates 

Navigating the Challenges of Vaso-Occlusive Crisis: A Guide for Patients and Caregivers 

An Overview Of Daunorubicin: What Is It Used For And How Does It Work? 

Magnetically Controlled Surgical Microdevices for Targeted Hematologic Tissue Intervention 

Whats more on Hidoc Dr.

Medical Updates
KOL Videos
Surveys
Events

Daily news to keep you up to date

Gain valuable insights with our in-depth KOL Video discussions

Participate and win cash vouchers

Get updates on the latest events happening around the world
Featured News
Featured Articles
Featured Events
Featured KOL Videos

1.

In 18 States, alcohol exclusion laws are still in effect.

2.

Mammo Responsibility Increases Screening; Opioids for Pain Related to Cancer? Ignored CRC Signs.

3.

Early-life exposure to air and light pollution linked to increased risk of pediatric thyroid cancer

4.

Financial hardship for cancer survivors due to high-cost immunotherapies, especially for blood cancer patients

5.

Cancer Warnings on Alcohol? Surge in GI Illnesses; Swab Detects Kids' Asthma Type

1.

Exploring the Causes and Treatments of Bacterial Keratitis: A Comprehensive Guide

2.

Risk Assessment of Cancer-Associated Thrombotic Events

3.

Preventing Developmental Iron Depletion in Childhood

4.

Risk Assessment of Cancer-Associated Endocrine Disorders

5.

Uncovering the Hidden Gallons: How Much Blood Is Inside the Human Body?

1.

International Cancer Conference

2.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

3.

International Cancer Conference

1.

A Comprehensive Guide to First Line Management of ALK Positive Lung Cancer - Part VII

2.

Current Scenario of Cancer- Palliative Care to Close the Care Gap

3.

Post Progression Approaches After First-line Third-Generaion ALK Inhibitors

4.

L858R Mutation- An Overview of Retrospective Cohort Study in Advanced NSCLC Patients

5.

Understanding Blood Clotting Disorders

Fastest Growing Medical Platform for Doctors

Address :
Hidoc Dr. Inc. | Delaware C Corp | 1309 Coffeen Ave. Suite 1200, Sheridan WY, 82801

Phone :
+1-415-463-3094

Email :
anishagadia@hidoc.co

Quick Links

Drug DatabaseDrug InteractionDiseases Database
KOL VideosKnowledge HubQuizzes
Medical UpdatesEventsAbout Us

© Copyright 2026 Hidoc Dr. Inc.

Terms & Conditions - LLP | Inc. | Privacy Policy - LLP | Inc. | Account Deactivation
Home
Profile
Login
bot