Constipation Linked to Greater Weight Loss on Semaglutide

Published Date: 05 May 2026

Patients on semaglutide who experienced constipation had greater weight loss than those without constipation, and genes could be at play.

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About 1 in 8 Danish care home residents with T2D admitted from 2018 to 2023 used glucose-lowering drugs, and most continued treatment despite having A1c levels below recommended targets.

With nearly half of patients discontinuing semaglutide within 12 months — especially younger adults — clinicians face a growing challenge in sustaining long-term treatment.
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