Does the new law start when animal research ends?

Published Date: 21 Mar 2023

Proponents say the new law in the United States signals the end of animal testing, and scientists predict animal models will still be needed.

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As new Medicaid work mandates start to take effect, patients in some states are asking physicians for waivers, saying they’re too sick or disabled to work. But rules for granting waivers are confusing.

More than 6 million Americans started GLP-1 drugs since 2021 — and a growing share had no documented medical reason for taking them.

Deaths from infection or sepsis increased from 2018 to 2021 but decreased in the following years.

Failure of an anti-inflammatory monoclonal antibody in the randomized trial shouldn’t be seen as negating the role of inflammation in atherosclerotic cardiovascular disease, some experts argued.

A new ACC/AHA guideline restores numeric LDL-C targets while a 150,000-patient CTT reassessment clears most label-listed statin side effects.

Migraine is linked to an earlier onset of stroke, yet young patients with stroke and a history of migraine experience better functional recovery at discharge.

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Pachychoroid Disease Progression Remains Low

Most eyes with pachychoroid features maintained their subtype over 2 years, with progression to pachychoroid neovasculopathy developing in only a small fraction of eyes.

Obesity Class III Linked to Death Risk in Younger Adults

Younger adults with severe obesity face significantly increased risk for mortality, while older adults show minimal differences across obesity classes.

Integrase Inhibitors Safe for Heart in HIV Patients

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Mild Tremor Tied to Cognitive Decline in Seniors

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Cefadroxil Effective for Gram-Positive Bacteremia

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Dapagliflozin Reduces AKI After Cardiac Surgery

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Dexrazoxane May Preserve LV Function in Cancer Survivors

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Photon-Counting CT Boosts Stent Fracture Detection

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Postpartum Health Coaching Boosts Blood Pressure Control

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Five Steps to Earlier Heart Failure Detection

Heart failure often hides behind vague complaints. These five primary care steps can help spot it earlier and guide faster, evidence-based treatment.

How to Talk About Exercise When Weight Loss Is Off the Table

In the era of GLP-1 drugs, weight loss is no longer a compelling pitch. Here’s how to reframe physical activity for patients.

Central Adiposity May Reclassify CVD Risk Beyond BMI

Among individuals with normal BMI, elevated waist circumference or waist-to-hip ratio may identify cardiovascular risk beyond BMI.

Allopurinol Offers No Heart Benefit in Kidney Donors

The use of allopurinol leads to significantly lower uric acid levels but shows no effect on heart mass, blood pressure, or insulin sensitivity in healthy living kidney donors, a phase 2b trial finds.

Cardiometabolic Index Can Predict Mortality Risk in T2D

A higher cardiometabolic index is linked to an increased risk for all-cause and cardiovascular mortality in patients with T2D, serving as an effective prognostic tool.

Quarter of Gestational Diabetes Moms Get Early Hypertension

More than 1 in 4 women with recent gestational diabetes developed hypertension at 5 months postpartum, driven primarily by baseline maternal characteristics rather than pregnancy complications.

Retatrutide Trims Weight and A1c in Diabetes

Retatrutide helped patients lose up to 30% of body weight in new trials, among the largest effects yet from a weight-loss drug – but a new safety signal raises questions.

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