Global Trial to Test Lifestyle Plus Metabolic Tx in Dementia

Published Date: 22 Jul 2026

A $100 million global trial will investigate whether adding a metabolism-targeting therapy to multidomain lifestyle intervention further reduces the risk of cognitive decline in older adults at risk for dementia.

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Todays Updates

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British lawmakers rejected on Friday a proposal to legalise assisted dying for terminally ill people, dealing a major setback to campaigners and bringing the latest effort...

Liberalized Cannabis Policies May Increase Substance Use

In a global review, legalization was associated with increased cannabis use and related emergency department visits, with potential decreases in the use of alcohol and tobacco.

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Researchers analyzed plasma samples collected from 313 patients with early breast cancer approximately 2 years after they had completed adjuvant chemotherapy.

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Patients who respond to neoadjuvant immunochemotherapy may be able to undergo less extensive surgery, with high rates of disease control and organ preservation.

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In patients with first- or second-line Philadelphia-positive B-cell acute lymphoblastic leukemia, favorable outcomes are observed with discontinuation of ponatinib.

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Latest News

Denmark's Novo Nordisk ⁠said on Thursday its blockbuster ⁠weight-loss drug Wegovy had ⁠been approved ‌in China as the first GLP-1 RA class of drugs for the ‌treatment of MASH.

Obesity is increasing faster among young adults worldwide, even as older adults still carry the greater overall burden, a new analysis of 196 countries over three decades finds.

About 1 in 8 Danish care home residents with T2D admitted from 2018 to 2023 used glucose-lowering drugs, and most continued treatment despite having A1c levels below recommended targets.

With nearly half of patients discontinuing semaglutide within 12 months — especially younger adults — clinicians face a growing challenge in sustaining long-term treatment.

An observational study finds a higher number of symptoms and greater severity among midlife women with type 2 diabetes than among those without.

Novo Nordisk’s phase 3b trial shows once-weekly IcoSema improves glycemic control and weight with less hypoglycemia than insulin glargine U100 in adults with type 2 diabetes.

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How to Help Manage Depression After GLP-1 Weight Regain

Offer realistic expectations when medication use ends and provide the tools to remain on track.

Indian Activists Lodge Concerns About Food Warning Proposal

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Keto Diet Outperforms Others in Liver Health in Obesity

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US Pentagon Issues Clinical Guidelines on Troop Testosterone Screening to Start Immediately

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From Hunger to Obesity: Developing World Faces Growing Threat to Child Health

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Earlier SGLT2 Use After AKI May Improve Outcomes

Earlier SGLT2 inhibitor use after dialysis-requiring AKI is linked to better kidney outcomes in patients with type 2 diabetes, with no increase in safety events.

New Tool Helps Clinicians Screen for Obesity’s Causes

Experts have developed a new 25-minute tool to screen patients for over 30 possible causes of obesity, from genetics to psychological trauma.

Too Weak, Too Strict: India's Food Warning Labels Draw Fire From All Sides

The Indian government is facing fierce opposition on proposed food warning labels from both health experts and food giants - activists say many items will escape scrutiny...

Early Childhood Obesity Linked to Adolescent Obesity Risk

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600,000 Seniors Have Signed Up for Obesity Drugs Under New Medicare Program

U.S. Centers for ⁠Medicare and Medicaid Services Administrator ⁠Dr. Mehmet Oz said ⁠on Monday ‌that 600,000 seniors have signed up to receive GLP-1 weight ‌loss medications...

Hims & Hers Offers GLP-1s, Men's Health Treatments in Australia

Telehealth company Hims & Hers has begun offering GLP-1 weight-loss drugs and other treatments ⁠to men in Australia as it continues to expand its international business.

Time-Restricted Eating Helps Sustain Weight Loss

New research shows an 8-hour eating window can help sustain weight loss for a year. Meal timing, alongside diet quality and exercise may be a useful, personalized tool.

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