Better health is associated with a higher risk of heart disease.

Published Date: 17 Feb 2023

UK: More health is associated with more cardiovascular disease (CVD) and higher triglycerides...

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Allopurinol Offers No Heart Benefit in Kidney Donors

The use of allopurinol leads to significantly lower uric acid levels but shows no effect on heart mass, blood pressure, or insulin sensitivity in healthy living kidney donors, a phase 2b trial finds.

Retatrutide Trims Weight and A1c in Diabetes

Retatrutide helped patients lose up to 30% of body weight in new trials, among the largest effects yet from a weight-loss drug – but a new safety signal raises questions.

Quarter of Gestational Diabetes Moms Get Early Hypertension

More than 1 in 4 women with recent gestational diabetes developed hypertension at 5 months postpartum, driven primarily by baseline maternal characteristics rather than pregnancy complications.

Cardiometabolic Index Can Predict Mortality Risk in T2D

A higher cardiometabolic index is linked to an increased risk for all-cause and cardiovascular mortality in patients with T2D, serving as an effective prognostic tool.

Three Midlife Risk Factors Linked to Earlier Dementia Onset

Smoking, diabetes, and hypertension in midlife are associated with nearly 13 fewer dementia-free years, underscoring the importance of vascular risk management.

Even Low Physical Activity May Lower Stroke Risk in AF

Even low levels of physical activity were linked to lower stroke and mortality risks in atrial fibrillation, with greater benefits generally seen at higher activity levels.

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SBRT vs IMRT: Better for Bowel Symptoms, Not Cancer Control

For men with intermediate-risk prostate cancer, SBRT may beat longer-course radiotherapy in some measures of quality of life, but not disease-free survival.

Can Electronic PRO Monitoring Ease Fatigue in Breast Cancer?

Weekly electronic symptom monitoring was associated with improved fatigue and physical functioning in a randomized trial of patients with metastatic breast cancer.

FDA Approves Iberdomide Combo for Multiple Myeloma

Outcomes improve when a novel, first-in-class immunomodulatory drug is combined with daratumumab and dexamethasone in previously treated patients.

Latest News

The use of allopurinol leads to significantly lower uric acid levels but shows no effect on heart mass, blood pressure, or insulin sensitivity in healthy living kidney donors, a phase 2b trial finds.

Retatrutide helped patients lose up to 30% of body weight in new trials, among the largest effects yet from a weight-loss drug – but a new safety signal raises questions.

More than 1 in 4 women with recent gestational diabetes developed hypertension at 5 months postpartum, driven primarily by baseline maternal characteristics rather than pregnancy complications.

A higher cardiometabolic index is linked to an increased risk for all-cause and cardiovascular mortality in patients with T2D, serving as an effective prognostic tool.

Smoking, diabetes, and hypertension in midlife are associated with nearly 13 fewer dementia-free years, underscoring the importance of vascular risk management.

Even low levels of physical activity were linked to lower stroke and mortality risks in atrial fibrillation, with greater benefits generally seen at higher activity levels.

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GLP-1s Work Better After Bariatric Surgery

Patients who start GLP-1s after bariatric surgery, not before, live longer and have fewer complications.

Healthy Grocery Delivery Curbs Blood Sugar Levels in T2D

A new study looks at the effect of home delivery of healthy groceries on A1c levels and food and nutrition security in vulnerable patients with type 2 diabetes.

How Braunwald Changed Medicine and Navigated Research Fraud

Genius or hard work? How did Eugene Braunwald become the father of modern cardiology.

Pregnancy Weight Gain, Hypertension Tied to JIA Risk in Kids

Higher weight gain and hypertensive disorders during pregnancy are associated with an increased risk for juvenile idiopathic arthritis in children, and prepregnancy BMI shows no association.

Cardiac Output Tied to Brain Volume in APOE-ε4 Carriers

Reduced cardiac output is associated with a smaller brain volume in older adults carrying the APOE-ε4 allele, but not in non-carriers, a study shows.

Braunwald’s Uncertain Beginnings and Concerns for the US

Eugene Braunwald’s life was full of close calls. Medscape spoke with cardiologist Thomas Lee about how he came to write the eminent physician’s biography and the last time he spoke with Braunwald.

Capillary Changes Tied to Higher Mortality in Raynaud's

Patients with early Raynaud's phenomenon who show both abnormal nailfold capillaries and positive antinuclear antibodies face a mortality pattern that diverges from those with neither marker.

Forward Head Posture Linked to Altered Spine Alignment

A radiographic analysis reveals that forward head posture involves shifts in the upper cervical and cervicothoracic regions with increased forward spinal balance.

Kidney Function Tied to Small Vessel Disease Marker

Stroke survivors with glomerular hyperfiltration show more enlarged perivascular spaces, while those with severely reduced kidney function have greater overall small vessel disease burden.

UK Becomes First in Europe to Approve New GLP-1 Pill

The MHRA approves orforglipron, making the UK the first country in Europe to approve the weight-loss and diabetes drug.

Plasma p-Tau217 Drop Tied to Better Outcomes on Lecanemab

Patients with Alzheimer's disease show distinct patterns of plasma p-tau217 reduction after starting lecanemab, and those with greater biomarker drops show more favorable cognitive trajectories.

Premature Menopause Linked to Higher Risk for Hypertension

Premature menopause before the age of 40 years is linked to a higher risk for hypertension than normal menopause after the age of 45 years.

Specific Food Ingredients Linked to Risk for Hypertension

Specific food ingredients used in ultraprocessing are linked to a higher risk of developing incident arterial hypertension, a large UK Biobank analysis finds.

Depression Mediates Link Between CAA and Cognitive Decline

Depressive symptoms are more likely in patients with cerebral amyloid angiopathy than in control individuals and partly explain the cognitive deficits in this population.

Levothyroxine Aids Heart Health in Kids With Hypothyroidism

Levothyroxine therapy may improve subtle left ventricular diastolic dysfunction in children with idiopathic subclinical hypothyroidism.

Smoky Air on Hot Days Linked to More Danger for the Heart

A multi-country study shows the impact of wildfire smoke exposure during a heatwave, prompting calls for cardiologists to protect their most vulnerable patients.

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