Discussing Safety, Tolerability of Tenapanor in Pediatric IBS-C patients, with Thomas Wallach, MD Thomas Wallach, MD

Published Date: 16 Dec 2025

Thomas Wallach, MD, discusses phase 3 safety data of tenapanor in pediatric patients with IBS-C, presented at the 2025 NASPGHAN Annual Meeting.

Read Full News

Latest News

Green Giant: How Taylor Farms Became a Top Salad Supplier Before US Diarrhea Outbreak

Taylor Farms, the produce supplier at the center of the massive U.S. cyclosporiasis outbreak, changed the way that America eats after launching branded, prepackaged and...

Cyclosporiasis Cases in US Climb to 15,716, CDC Says

The Centers for Disease Control and Prevention on Tuesday reported 15,716 confirmed cases of ⁠cyclosporiasis in the United States, an increase of 1,821 cases from a week...

Quebec Opposes Lowering Colorectal Cancer Screening Age

Quebec’s health ministry is opposing experts’ recommendation to lower the colorectal cancer screening age to 45 years.

Colon Capsule Endoscopy: Why It Fails

In colon capsule endoscopy, chronic opioid use is linked to incomplete examinations and inadequate bowel preparation, whereas diabetes is tied to poorer bowel preparation.

Can Steroids Reduce Complications of GI Surgeries?

Researchers randomized about 1200 patients undergoing elective surgery for digestive cancer to receive either methylprednisolone or placebo at anesthesia induction.

Is the Combination of GLP-1s and Clozapine Safe?

Gastrointestinal hypomotility is the most lethal adverse event linked to clozapine use. GLP-1s slow the gut too. Clinicians are combining the two, with little safety data to guide them.

Todays Updates

Hyponatremia Risk Varies Among Second-Gen Antipsychotics

Aripiprazole is associated with a lower risk for hyponatremia compared with olanzapine in patients treated with second-generation antipsychotics, a new cohort study shows.

HCT Survival Outcomes Improving in Relapsed Hodgkin Lymphoma

Researchers evaluate changes in post-transplantation outcomes among patients with relapsed or refractory Hodgkin lymphoma from 2010 to 2022.

How Much of a Cancer Drug Is Too Much?

In a recent KFF survey, 43% of US adults said they had skipped their medication in the past year because of cost.

Todays Updates

Hyponatremia Risk Varies Among Second-Gen Antipsychotics

Aripiprazole is associated with a lower risk for hyponatremia compared with olanzapine in patients treated with second-generation antipsychotics, a new cohort study shows.

HCT Survival Outcomes Improving in Relapsed Hodgkin Lymphoma

Researchers evaluate changes in post-transplantation outcomes among patients with relapsed or refractory Hodgkin lymphoma from 2010 to 2022.

How Much of a Cancer Drug Is Too Much?

In a recent KFF survey, 43% of US adults said they had skipped their medication in the past year because of cost.

Latest News

Taylor Farms, the produce supplier at the center of the massive U.S. cyclosporiasis outbreak, changed the way that America eats after launching branded, prepackaged and...

The Centers for Disease Control and Prevention on Tuesday reported 15,716 confirmed cases of ⁠cyclosporiasis in the United States, an increase of 1,821 cases from a week...

Quebec’s health ministry is opposing experts’ recommendation to lower the colorectal cancer screening age to 45 years.

In colon capsule endoscopy, chronic opioid use is linked to incomplete examinations and inadequate bowel preparation, whereas diabetes is tied to poorer bowel preparation.

Researchers randomized about 1200 patients undergoing elective surgery for digestive cancer to receive either methylprednisolone or placebo at anesthesia induction.

Gastrointestinal hypomotility is the most lethal adverse event linked to clozapine use. GLP-1s slow the gut too. Clinicians are combining the two, with little safety data to guide them.

News All Time

Acting US FDA Chief Urges Confidence in Lettuce as Agency Updates Produce Safety Guidance

Acting U.S. FDA Commissioner Kyle Diamantas said on Tuesday Americans should feel confident in eating fresh produce, as the agency has finalized guidance for proper...

Listeriosis Incidence Stable Despite Aging Population

The incidence of invasive listeriosis has remained stable in the US from 2008 to 2023, although certain groups face disproportionately higher rates.

‘Concerning’ Trends in Cancer Drug Approvals

FDA approvals for solid tumor drugs increasingly rely on response rates as the primary evidence supporting approval rather than overall survival.

What to Know About the Multistate Salmonella Outbreak in the US

(Removes abbreviation in paragraph 2 and makes 'salmonella' lowercase throughout)

US FDA to Hold Advisory Meeting to Review Grail's Multi-cancer Test

Grail said on Friday the U.S. FDA plans to hold a meeting of outside experts to review its multi-cancer screening test ⁠Galleri in September, sending its shares up...

US Cyclosporiasis Probe Linked to Lettuce Widens to 15 States

U.S. health authorities have widened their probe into a cyclosporiasis outbreak tied to iceberg lettuce from central Mexico after detecting cases in six additional states,...

Mexican Jalapenos Tied to Salmonella Outbreak in 27 US States

U.S. health officials are investigating a Salmonella outbreak linked to Mexican jalapeno peppers that has sickened 345 people in 27 states, prompting supplier ⁠Coast Citrus...

Genetic Marker Linked to Severe Outcomes Across IBD Subtypes

HLA-DRB1*01:03 may serve as a genetic marker for severe outcomes across IBD phenotypes and help identify patients at higher risks for surgery and treatment failure.

Does High-Dose Vitamin D3 Supplementation Improve CRC Survival?

A phase 3 trial was conducted to confirm the benefit of high-dose vitamin D3 supplementation in patients with previously untreated metastatic CRC that was seen in a phase 2 trial.

IV Vitamin C With Chemo Shows Signals in Cancer Care

A phase 2 study reported a longer median overall survival in patients receiving IV ascorbate with chemotherapy, although larger randomized trials are needed to confirm the finding.

Small Colorectal Lesions Carry Risk for Deep Invasion

Non-pedunculated colorectal lesions smaller than 2 cm may harbor deep submucosal invasion despite their diminutive size, study finds.

Etrasimod Effective As First-Line Advanced UC Therapy

Etrasimod can be an effective and safe first-line advanced therapy option in patients with ulcerative colitis who escalate after conventional treatment failure.

Does Doublet Chemotherapy Improve Survival in Rectal Cancer?

Patients with high-risk locally advanced rectal cancer were randomly assigned to receive doublet-LC TNT or conventional neoadjuvant chemoradiotherapy.

Radiation Boost Linked to Better Survival in Rectal Cancer

A phase 2 trial finds that adding a modest radiation boost improves 9-year survival without increasing toxicity, despite no improvement in pathologic complete response.

Creatinine Assay Bias Affects MELD Scoring

Bilirubin interference in commonly used creatinine assays artificially inflates MELD scores in liver transplant candidates, a study reports.

EHR Marker May Help Curb Risk for Liver Transplant Rejection

A remote intervention aimed at improving medication adherence may reduce organ rejection in liver transplant recipients at high risk.

Recommended News For You

Key mechanism behind prostate cancer drug resistance reveals potential new treatment strategy

Number of cancer survivors in the US reaches 18.6 million—projected to exceed 22 million by 2035

The Benefits of Exercise for Substance Use Disorders.

Integrative palliative care is critical to improving mental health among pancreatic cancer patients

Le cancer et le COVID ont conduit le patient à une double transplantation de poumon.

Dual Targeted CAR-T Yields 99% Response Rate in Pediatric ALL

Study reveals link between new-onset type 2 diabetes and some obesity-related cancers

Recommended Articles For You

Exploring the Unseen: Carcinoid Syndrome and its Impact on Quality of Life 

Functional Iron Reserve Screening Before Clinical Deficiency: Clinical Insights and Evidence-Based Strategies 

Revolutionizing Oncology: AI in Radiology, Machine Learning in Pathology, and Deep Learning for Cancer Detection 

Essential Strategies in Hematology for Healthcare Excellence 

Whats more on Hidoc Dr.

Medical Updates
KOL Videos
Surveys
Events

Daily news to keep you up to date

Gain valuable insights with our in-depth KOL Video discussions

Participate and win cash vouchers

Get updates on the latest events happening around the world
Featured News
Featured Articles
Featured Events
Featured KOL Videos

1.

Is It Really Cancer? More Concerns About Accelerated Approval; Metformin and Cancer

2.

Pediatric high-grade gliomas: Research reveals effective targeting with avapritinib

3.

In prostate cancer survivorship, sleep disturbances are underappreciated.

4.

Study shows supervised exercise improves strength, physical performance in patients with advanced breast cancer

5.

a cutting-edge cancer diagnostic tool.

1.

Therapeutic Innovations Through Germline Predisposition in Acute Leukemias and Myeloid Neoplasms

2.

Community Survivorship Networks for Long-Term Cancer Wellness

3.

Neuroendocrine Tumors: Case Study on Diagnosis, Treatment Strategies & Patient Management

4.

Targeted Therapies for Breast Cancer: What’s New?

5.

Integrated Insights in Hematology and Quality Improvement

1.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

2.

International Cancer Conference

3.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

4.

Asian Symposium on Advancement in Hematology and Oncology

5.

Asian Symposium on Advancement in Hematology and Oncology

1.

Management of 1st line ALK+ mNSCLC (CROWN TRIAL Update) - Part IV

2.

Hands-on Workshop: Hematology

3.

Targeting Oncologic Drivers with Dacomitinib: A New Approach to Lung Cancer Treatment

4.

Molecular Contrast: EGFR Axon 19 vs. Exon 21 Mutations - Part III

5.

Learning About Different Treatment Approaches For Acute Lymphoblastic Leukemia

Fastest Growing Medical Platform for Doctors

Address :
Hidoc Dr. Inc. | Delaware C Corp | 1309 Coffeen Ave. Suite 1200, Sheridan WY, 82801

Phone :
+1-415-463-3094

Email :
anishagadia@hidoc.co

Quick Links

Drug DatabaseDrug InteractionDiseases Database
KOL VideosKnowledge HubQuizzes
Medical UpdatesEventsAbout Us

© Copyright 2026 Hidoc Dr. Inc.

Terms & Conditions - LLP | Inc. | Privacy Policy - LLP | Inc. | Account Deactivation
Home
Profile
Login
bot