Zepbound's Weight Loss, Cardiometabolic Benefits Hold Up at 3 Years

Published Date: 11 Nov 2024

Nearly all participants in SURMOUNT-1 avoided diabetes with the GLP-1/GIP receptor agonist

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Resistance Training May Lower Risk for T2D

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Metabolic Issues Show Up Early and Often With ARPI Therapy

A new study underscores the importance of monitoring patients’ cardiometabolic health soon after starting ADT plus ARPI therapy for prostate cancer.

Brain Networks Tied to Post-Stroke Dizziness

A lesion network analysis reveals cerebellar and occipital regions consistently associated with dizziness after ischemic stroke, regardless of lesion location or symptom subtype.

Women Make Up Small Percentage of Trial Leaders for SHD

Women make up less than 10% of oversight committee seats for interventional structural heart disease trials, although women are being studied more intently than ever before.

AI Stethoscopes May Aid Early CVD Detection

AI-powered stethoscopes are showing promise in primary care, with new evidence suggesting improved detection of heart failure, atrial fibrillation, and valvular disease.

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Most Family Physicians Struggle With After-Hours Admin Work

Most family physicians face heavy administrative burden, but improved electronic health records and staff support may help to ease some of the load.

'Just Bloating': Stop Dismissing This Common GI Complaint

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Immunotherapy Promises New Era in Cancer Prevention

Prof David Kerr explores whether PD-1 inhibitors and targeted vaccines can regress polyps and prevent secondary cancers in Lynch syndrome.

HF Hospitalizations and Telehealth Coverage Parity Laws

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Many Clinical Paths Are Open to NPs. Here’s Help in Picking

‘A strength of the nurse practitioner profession is its versatility,’ one expert says.

Nurses Speak Out on Burnout, Mandatory Overtime, and Burning the Candle at Both Ends

Emotionally drained, sleep-deprived, and skipping meals to keep up: what nurse leaders say needs to change to prevent burnout.

Most Family Physicians Struggle With After-Hours Admin Work

Most family physicians face heavy administrative burden, but improved electronic health records and staff support may help to ease some of the load.

'Just Bloating': Stop Dismissing This Common GI Complaint

Bloating is one of patients' most common gastrointestinal complaints. Dr Alicia Muratore kicks off this six-part series by asking why bloating is often treated as an afterthought.

S1 Episode 4: Urinary Tract Infections and Sexual Function

Drs Anne Lenore Ackerman and Rachel S. Rubin discuss urinary tract infections, sexual function, quality of life, and the importance of patient education.

Immunotherapy Promises New Era in Cancer Prevention

Prof David Kerr explores whether PD-1 inhibitors and targeted vaccines can regress polyps and prevent secondary cancers in Lynch syndrome.

HF Hospitalizations and Telehealth Coverage Parity Laws

State telehealth coverage parity laws require private insurers to cover outpatient telehealth visits increasing access for HF patients. This analysis examines whether this affected clinical outcomes.

Latest News

Migraine is linked to an earlier onset of stroke, yet young patients with stroke and a history of migraine experience better functional recovery at discharge.

An analysis using data from three long-running studies on the effect of lifestyle and health provides more support for consistent use of resistance training with aging.

A new study underscores the importance of monitoring patients’ cardiometabolic health soon after starting ADT plus ARPI therapy for prostate cancer.

A lesion network analysis reveals cerebellar and occipital regions consistently associated with dizziness after ischemic stroke, regardless of lesion location or symptom subtype.

Women make up less than 10% of oversight committee seats for interventional structural heart disease trials, although women are being studied more intently than ever before.

AI-powered stethoscopes are showing promise in primary care, with new evidence suggesting improved detection of heart failure, atrial fibrillation, and valvular disease.

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Dapagliflozin Reduces AKI After Cardiac Surgery

Four doses of the SGLT2 inhibitor dapagliflozin reduce acute kidney injury risk after elective cardiac surgery, with a low incidence of ketoacidosis.

Dexrazoxane May Preserve LV Function in Cancer Survivors

Researchers analyzed echocardiographic data from patients who received dexrazoxane before doxorubicin as part of their treatment for cancer in childhood.

Photon-Counting CT Boosts Stent Fracture Detection

A phantom study shows that photon-counting detector CT significantly improves the detection of visceral endovascular stent fractures compared with conventional CT.

Postpartum Health Coaching Boosts Blood Pressure Control

Health coaching may help close a critical gap in care after a hypertensive pregnancy.

Five Steps to Earlier Heart Failure Detection

Heart failure often hides behind vague complaints. These five primary care steps can help spot it earlier and guide faster, evidence-based treatment.

How to Talk About Exercise When Weight Loss Is Off the Table

In the era of GLP-1 drugs, weight loss is no longer a compelling pitch. Here’s how to reframe physical activity for patients.

Central Adiposity May Reclassify CVD Risk Beyond BMI

Among individuals with normal BMI, elevated waist circumference or waist-to-hip ratio may identify cardiovascular risk beyond BMI.

Allopurinol Offers No Heart Benefit in Kidney Donors

The use of allopurinol leads to significantly lower uric acid levels but shows no effect on heart mass, blood pressure, or insulin sensitivity in healthy living kidney donors, a phase 2b trial finds.

Retatrutide Trims Weight and A1c in Diabetes

Retatrutide helped patients lose up to 30% of body weight in new trials, among the largest effects yet from a weight-loss drug – but a new safety signal raises questions.

Quarter of Gestational Diabetes Moms Get Early Hypertension

More than 1 in 4 women with recent gestational diabetes developed hypertension at 5 months postpartum, driven primarily by baseline maternal characteristics rather than pregnancy complications.

Cardiometabolic Index Can Predict Mortality Risk in T2D

A higher cardiometabolic index is linked to an increased risk for all-cause and cardiovascular mortality in patients with T2D, serving as an effective prognostic tool.

Three Midlife Risk Factors Linked to Earlier Dementia Onset

Smoking, diabetes, and hypertension in midlife are associated with nearly 13 fewer dementia-free years, underscoring the importance of vascular risk management.

Even Low Physical Activity May Lower Stroke Risk in AF

Even low levels of physical activity were linked to lower stroke and mortality risks in atrial fibrillation, with greater benefits generally seen at higher activity levels.

Timing of Thrombolysis Matters in Patients With Mild Stroke

In patients with ischaemic stroke, intravenous thrombolysis given within 90 minutes of symptom onset improves functional outcomes, but the benefit fades progressively beyond this window.

BP Variability Tied to White Matter Lesion Growth

Higher visit-to-visit variability in systolic blood pressure is linked to faster progression of white matter lesions in patients at high cardiovascular risk, a study finds.

Iron Testing Gap Seen in Patients With New Heart Failure

Iron deficiency testing remains inconsistent among patients with incident heart failure in UK primary care, with variation by age, sex, and presence of long-term conditions.

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