In obese NAFLD patients, bariatric surgery may improve cardiovascular health.

Published Date: 24 Apr 2023

According to a recent study, bariatric surgery reduced incident cardiovascular disease and composite cardiovascular adverse outcomes by almost 50%.

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FDA Neurology Roundup: May 2026

A monthly snapshot of FDA activity involving therapies for the prevention and treatment of neurologic diseases.

Solutions Emerging for Post-GLP-1 Weight Regain

As real-world studies show high rates of GLP-1 discontinuation and rapid weight regain, new interventions may help patients maintain weight loss.

Digoxin Shows Signs of a Heart Failure Revival

New trial data from the Heart Failure 2026 conference suggest that low-dose digoxin may reduce worsening HF events, reigniting debate over digitalis therapy.

Hidden Heart Disease Found in At-Risk Communities

Silent MIs and undiagnosed heart disease were common in deprived and ethnically diverse communities — found via primary care and social media.

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Teen Fitness Tied to Early AF Risk, Later CVD Benefit

In men, high adolescent cardiorespiratory fitness is linked to a small excess risk for atrial fibrillation in early adulthood but larger reductions in the risk for other cardiovascular events later on.

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Fuzuloparib Add-On Improves Metastatic Prostate Cancer rPFS

Researchers track progression-free survival after adding a PARP inhibitor to a standard regimen for metastatic castration-resistant prostate cancer.

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Isatuximab Boosts MRD Negativity in Multiple Myeloma

Researchers compare two different treatment regimens in 446 transplant-ineligible patients with newly diagnosed multiple myeloma in a global phase 3 trial.

Novel ADC Improves Survival in Metastatic TNBC

Izalontamab brengitecan extends overall survival among patients with metastatic TNBC, but it’s unclear how the investigational therapy might fit into an evolving treatment landscape.

Proton Therapy Fails to Beat IMRT in Prostate Cancer

For men with localized prostate cancer, proton therapy looks no better than IMRT when it comes to 3-year biochemical progression or GI toxicity.

Fuzuloparib Add-On Improves Metastatic Prostate Cancer rPFS

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Latest News

A monthly snapshot of FDA activity involving therapies for the prevention and treatment of neurologic diseases.

As real-world studies show high rates of GLP-1 discontinuation and rapid weight regain, new interventions may help patients maintain weight loss.

New trial data from the Heart Failure 2026 conference suggest that low-dose digoxin may reduce worsening HF events, reigniting debate over digitalis therapy.

Silent MIs and undiagnosed heart disease were common in deprived and ethnically diverse communities — found via primary care and social media.

Among patients with ANCA-positive vasculitis and severe kidney involvement, older age and low serum albumin levels at diagnosis are independent predictors of long-term mortality.

In men, high adolescent cardiorespiratory fitness is linked to a small excess risk for atrial fibrillation in early adulthood but larger reductions in the risk for other cardiovascular events later on.

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Proteinuria in Preeclampsia Tied to Hypertension & CKD Risks

Among women with preeclampsia, high levels of urinary protein excretion are associated with increased long-term risks for hypertension and chronic kidney disease.

Cycling Linked to Higher Arrhythmia Risk in Middle-Aged Men

More hours of lifetime endurance exercise are linked to increased odds of reporting atrial fibrillation or atrial flutter in middle aged men, and cycling shows an independent association.

FDA-Cleared ACORYS: Catheter-Free Cardiac Mapping

Noninvasive mapping with hundreds of body surface electrodes transforms the inverse ECG problem, letting AI and models infer intracardiac activation without catheter insertion.

Certain BP Drugs and Combos Better Tolerated Than Others

BP-lowering regimens with angiotensin receptor blockers are linked to a lower risk for discontinuation due to adverse events, while other drugs and combinations are linked to higher risk.

Pemvidutide Shows Liver and Cardiovascular Benefits in MASH

Pemvidutide improves fibrosis markers, liver fat, lipids, weight, and blood pressure in patients with MASH at 1 year, phase 2b data show.

Tackling Barriers to Lipid Management in Primary Care

Experts at the Primary Care Show identified the key barriers to lipid management — and what clinicians can do about them.

AI Spots Undertreated Heart Failure Risk Early

An AI tool applied to NHS health records identified stable-appearing heart failure patients who were undertreated and at high risk before hospital admission.

Daptomycin May Match Vancomycin in Resistant Endocarditis

Daptomycin offers similar effectiveness to vancomycin in treating left-sided infective endocarditis caused by methicillin-resistant staphylococci and is associated with a better safety profile.

Metabolic Changes Prompt Alcohol Cravings in AUD, Obesity

People with comorbid alcohol use disorder and obesity may represent a distinct clinical subgroup, with glucose dysregulation driving alcohol craving and the risk for relapse.

Treat the Overlap Between Long COVID and Chronic Fatigue

As more patients seek help for myalgic encephalomyelitis/chronic fatigue syndrome and similar symptoms for long COVID, primary care clinicians play a bigger role in treatment.

Nighttime BP Measured Using Wrist Device Reveals Heart Risks

Nighttime blood pressure measured at home with a wrist-worn device is independently associated with the odds of left ventricular hypertrophy, beyond office and morning measurements.

Does Obesity Drive Related Conditions in Older Adults?

Many health conditions related to obesity are common in older adults, but some are more attributable to obesity than others.

Higher Abdominal Fat Linked to Faster Biological Aging

Higher abdominal fat is associated with accelerated biological aging across multiple measures, and metabolic aging explains much of the increased risks for heart disease and death.

Beyond the Mediterranean Diet: What’s Next for Gut Health?

Emerging data suggest Western dietary patterns may promote inflammatory gut changes, whereas traditional diets appear linked to more favorable metabolic effects.

The Unsung Advantages of Unilateral Strength Training

Strength coaches agree that pretty much everyone, whether you’re 25 or 85, should train unilaterally — doing exercises that allow arms and legs to move independently.

Add-On Alteplase May Aid Stroke Recovery Post-Thrombectomy

Adjunctive intra-arterial alteplase after successful thrombectomy may aid functional recovery compared to thrombectomy alone in large vessel occlusion stroke, new data show.

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