First-in-human trial shows promising results for antibody-drug conjugate in relapsed small cell lung cancer

Published Date: 08 Sep 2025

A first-in-human Phase I study of SHR-4849 (IDE849), a Delta-like ligand 3 (DLL3)-directed antibody-drug conjugate (ADC), demonstrated manageable safety and early signs of anti-tumor activity in patients with relapsed small ...

Read Full News

Latest News

As Federal Loan Cap Takes Effect, Medical Schools Step Up

Medical schools are reaching out to inform students and make more funds available after federal help shrinks. Students debate best options.

Brain Age Tied to Dementia Risk in Those With Memory Issues

An automated MRI measure shows that each extra year the brain appears older than chronologic age is linked to increased dementia risk, especially in patients with subjective cognitive concerns.

Talk Therapy for Mental Health Not So Effective in ADHD

Adults with ADHD show improvement after psychological therapy for depression and anxiety, but they are less likely than those without ADHD to achieve reliable improvement or recovery.

Microcytic Anemia Patterns Differ by Sex in Teens

Adolescent females show a steady increase in the prevalence of microcytic anemia throughout their teenage years, while males show the opposite trend.

Whole Foods Recalls Items Containing Jalapenos on Potential Salmonella Contamination

Whole Foods said on Wednesday it was recalling select products from its produce and prepared foods departments that contain jalapenos ⁠sourced from Coast Citrus Distributors...

Med Schools Welcome Class of 2030 With White Coat Ceremonies

Thousands of newly minted med students took the first steps on their journey in medicine.

Todays Updates

Belgian Algorithm Reshapes Endometrial Cancer Care

A new Belgian algorithm may help clinicians choose adjuvant therapy more precisely in early endometrial cancer, moving beyond TNM staging alone.

Todays Updates

Belgian Algorithm Reshapes Endometrial Cancer Care

A new Belgian algorithm may help clinicians choose adjuvant therapy more precisely in early endometrial cancer, moving beyond TNM staging alone.

Latest News

Medical schools are reaching out to inform students and make more funds available after federal help shrinks. Students debate best options.

An automated MRI measure shows that each extra year the brain appears older than chronologic age is linked to increased dementia risk, especially in patients with subjective cognitive concerns.

Adults with ADHD show improvement after psychological therapy for depression and anxiety, but they are less likely than those without ADHD to achieve reliable improvement or recovery.

Adolescent females show a steady increase in the prevalence of microcytic anemia throughout their teenage years, while males show the opposite trend.

Whole Foods said on Wednesday it was recalling select products from its produce and prepared foods departments that contain jalapenos ⁠sourced from Coast Citrus Distributors...

Thousands of newly minted med students took the first steps on their journey in medicine.

News All Time

Prostate Surgery Leakage Improves Over 12 Months

About 1 in 5 patients develop urinary incontinence 3 months after thulium fiber laser enucleation of the prostate, with rates decreasing over 12 months.

Age and MRI Features Predict MS Odds After Initial Symptoms

Younger age at onset, multifocal symptoms, and specific MRI findings are associated with increased odds of multiple sclerosis diagnosis after a first demyelinating event.

Nirsevimab Linked to Lower Risk for IPD Hospitalizations

Nirsevimab immunization in children younger than 12 months is linked to a lower risk for hospitalization for invasive pneumococcal disease, a French nationwide analysis shows.

‘Big Beautiful’ Law Tests Rural Hospital Lifeline

A century-old hospital near Michigan’s southern border was one of the nation’s first to convert into a new emergency-focused model Congress created to save rural care.

Romanian Healthcare Workers End Strike Over Pay, Staffing

Romanian healthcare workers ended a nationwide strike on ⁠Friday as the country's caretaker government approved new hires in ⁠short-staffed state hospitals.

Swimming Linked to Reduced Disability in Low Back Pain

Swimming plus education is more effective than education alone in reducing disability in adults with chronic low back pain over 8 weeks, a trial shows.

Preterm Lung Disease: One Drug Testing May Miss Responders

Most children born premature with chronic lung disease have reversible airway obstruction, but bronchodilator responses vary widely, underscoring the need for individualized testing.

Vancomycin Prophylaxis Tied to Lower C difficile Recurrence

In children and young adults with cancer, oral vancomycin prophylaxis during broad-spectrum antibiotic therapy is associated with a lower risk for recurrent Clostridioides difficile infection.

Spousal Dementia Tied to Higher Dementia Risk

Spouses of individuals with dementia have a significantly higher risk of developing dementia, new research shows.

Romanian Healthcare Workers Strike Over Wage Bill Needed to Secure EU Funds

Thousands of Romanian doctors, nurses and other health workers went on an indefinite strike ⁠for the first time in a decade on Tuesday, protesting job freezes and a public...

Infections Tied to Increased Risk for Brain Disorders

Hospitalization due to an acute infection, especially infectious encephalitides, is linked to increased risk for psychiatric and neurologic disorders, a new study shows.

The Restorative Power of ‘Sacred Moments’ in Medicine

Deep human connection can be a potent antidote to burnout. Here’s how to cultivate meaning in an increasingly rushed healthcare system.

US FDA Approves Outlook Therapeutics' Eye Disease Drug

Outlook Therapeutics said on Friday the U.S. Food and Drug Administration has approved its drug for ⁠a type of eye disease that can cause vision loss.

Nasal IgA Protects Against H1N1, SARS-CoV-2 Infections

High baseline nasal IgA, not serum IgG, was linked to lower risk for influenza A H1N1 infection in a real-world study.

Punchlines and Pathology: The Secrets of Laughter Explained

A new review of data from patients with epilepsy describes two distinct neural networks, offering clinicians and patients a way to better understand laughter as a neurologic malfunction.

Gene Therapy Delivers Sustained Retinal Protection

People with age-related macular degeneration maintain vision and cut their need for supplemental injections by 90% 5 years after receiving gene therapy.

Recommended News For You

Orca-T Approved to Prevent GVHD After Stem Cell Transplant for Blood Cancers

The Early Progression of Prostate Cancer Is Not Stopped by Metformin.

Toward rapid and comprehensive genetic diagnosis of pediatric cancer through adaptive sequencing

Low-Dose Radiation Provides Almost Perfect Control Over Slow-Growing Lymphoma.

Global warming could be driving up women's cancer risk, find researchers

Enhanced CAR T cell therapy offers new strategy for lymphoma

Urinary tract cancer prediction models with high sensitivity and specificity

Recommended Articles For You

Exploring The Science Of Hematopoietic Stem Cell Transplantation: What You Need To Know 

Revolutionizing Thyroid Cancer: Advances in Molecular Genetics and Personalized Treatment Approaches 

Uncovering Breast Cancer: The Power of Early Stage Ultrasound 

Rehabilitation of Hand Dexterity Following Hematologic Treatment-Associated Deconditioning 

Whats more on Hidoc Dr.

Medical Updates
KOL Videos
Surveys
Events

Daily news to keep you up to date

Gain valuable insights with our in-depth KOL Video discussions

Participate and win cash vouchers

Get updates on the latest events happening around the world
Featured News
Featured Articles
Featured Events
Featured KOL Videos

1.

Short Shrift in Cancer Funding; Bypassing Familiar for Distant; Testing for BRCA.

2.

Pre-operative evaluation of ovarian cancer patients using DWI-MRI is helpful.

3.

Rural colon cancer patients face higher risks, but minimally invasive surgery could narrow gap

4.

Novel topical fluorescent imaging technique rapidly and safely detects basal cell carcinoma

5.

Potential new therapy for childhood brain cancer could heal treatment-resistant tumors

1.

What is Hemorrhagic Cystitis and How to Manage its Symptoms

2.

How Digital Innovation and AI-Powered Case Studies are Revolutionizing Oncology Education?

3.

Blood Donation Sustainability Through Behavioral Science

4.

Emerging Therapies and Technologies Reshaping Oncology: Innovations and Impact in 2025

5.

Essential Developments in Oncology for Healthcare Excellence

1.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

2.

International Cancer Conference

3.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

4.

Asian Symposium on Advancement in Hematology and Oncology

5.

Asian Symposium on Advancement in Hematology and Oncology

1.

Targeting Oncologic Drivers with Dacomitinib: A New Approach to Lung Cancer Treatment

2.

Navigating the Complexities of Ph Negative ALL - Part XVI

3.

Molecular Contrast: EGFR Axon 19 vs. Exon 21 Mutations - Part VI

4.

Molecular Contrast: EGFR Axon 19 vs. Exon 21 Mutations - Part V

5.

Molecular Contrast: EGFR Axon 19 vs. Exon 21 Mutations - Part VII

Fastest Growing Medical Platform for Doctors

Address :
Hidoc Dr. Inc. | Delaware C Corp | 1309 Coffeen Ave. Suite 1200, Sheridan WY, 82801

Phone :
+1-415-463-3094

Email :
anishagadia@hidoc.co

Quick Links

Drug DatabaseDrug InteractionDiseases Database
KOL VideosKnowledge HubQuizzes
Medical UpdatesEventsAbout Us

© Copyright 2026 Hidoc Dr. Inc.

Terms & Conditions - LLP | Inc. | Privacy Policy - LLP | Inc. | Account Deactivation
Home
Profile
Login
bot