CDK4/6 Inhibition in Breast Cancer: First or Second Line?

Published Date: 10 Jun 2023

First-line CDK4/6 inhibitor therapy did not improve overall survival or progression-free survival in patients with advanced ER+/HER2? breast cancer compared to second-line treatment.

Read Full News

Latest News

The next great performance booster for athletes? Sleep

When we think of elite athletes, we generally think of people who are at the top of their game physically.

Ablation reduces stroke risk for atrial fibrillation and may remove need for some types of blood thinners

A minimally invasive heart procedure to correct irregular heart rhythms called catheter ablation may reduce the risk of stroke enough that some patients can discontinue blood thinners, according to a preliminary late-breaking ...

Earlier blood transfusion may reduce heart failure, arrhythmia in adults with heart disease

An earlier blood transfusion—done when hemoglobin levels were higher—after major general or vascular surgery among people with heart disease was associated with a lower risk of some complications but not the most severe ...

Preparing for a tough exam? A tough gym workout could help with your studies

A new study by researchers at Coventry University has found a high-intensity gym workout appears to increase your ability to focus, remember and process information in your brain.

Frankenstein: Could an assembled body ever breathe, bleed or think? Anatomists explain

Frankenstein's creature is coming back to life—again. As Guillermo del Toro's new adaptation of Mary Shelley's gothic masterpiece airs on Netflix, we provide an anatomist's perspective of her tale of reanimation. Could ...

Biomaterial vaccines could make implanted orthopedic devices safer

Patients with implanted medical devices like orthopedic joint replacements, pacemakers, and artificial heart valves run a small but significant risk that these devices get infected with bacterial pathogens. This starts them ...

Todays Updates

Hyponatremia Risk Varies Among Second-Gen Antipsychotics

Aripiprazole is associated with a lower risk for hyponatremia compared with olanzapine in patients treated with second-generation antipsychotics, a new cohort study shows.

HCT Survival Outcomes Improving in Relapsed Hodgkin Lymphoma

Researchers evaluate changes in post-transplantation outcomes among patients with relapsed or refractory Hodgkin lymphoma from 2010 to 2022.

How Much of a Cancer Drug Is Too Much?

In a recent KFF survey, 43% of US adults said they had skipped their medication in the past year because of cost.

Todays Updates

Hyponatremia Risk Varies Among Second-Gen Antipsychotics

Aripiprazole is associated with a lower risk for hyponatremia compared with olanzapine in patients treated with second-generation antipsychotics, a new cohort study shows.

HCT Survival Outcomes Improving in Relapsed Hodgkin Lymphoma

Researchers evaluate changes in post-transplantation outcomes among patients with relapsed or refractory Hodgkin lymphoma from 2010 to 2022.

How Much of a Cancer Drug Is Too Much?

In a recent KFF survey, 43% of US adults said they had skipped their medication in the past year because of cost.

Latest News

When we think of elite athletes, we generally think of people who are at the top of their game physically.

A minimally invasive heart procedure to correct irregular heart rhythms called catheter ablation may reduce the risk of stroke enough that some patients can discontinue blood thinners, according to a preliminary late-breaking ...

An earlier blood transfusion—done when hemoglobin levels were higher—after major general or vascular surgery among people with heart disease was associated with a lower risk of some complications but not the most severe ...

A new study by researchers at Coventry University has found a high-intensity gym workout appears to increase your ability to focus, remember and process information in your brain.

Frankenstein's creature is coming back to life—again. As Guillermo del Toro's new adaptation of Mary Shelley's gothic masterpiece airs on Netflix, we provide an anatomist's perspective of her tale of reanimation. Could ...

Patients with implanted medical devices like orthopedic joint replacements, pacemakers, and artificial heart valves run a small but significant risk that these devices get infected with bacterial pathogens. This starts them ...

News All Time

How's your hydration? A new tool from researchers helps athletes find out

Researchers at the Korey Stringer Institute (KSI) in the College of Agriculture, Health and Natural Resources (CAHNR) have created an open-access document to help athletes, coaches, and parents understand the latest research ...

From monkey glands to 'young blood': The long, strange history of chasing immortality through transplants

When Russian president Vladimir Putin visited Beijing in September 2025, he told Chinese leader Xi Jinping that repeated organ transplants might make a person "get younger" and even live to 150. The remark was widely dismissed ...

Sentinel lymph node biopsy noninferior to lymphadenectomy in cervical cancer

For patients with early-stage cervical cancer, sentinel lymph node biopsy alone is noninferior to lymphadenectomy with respect to disease-free survival, according to a study published online Oct. 15 in the New England Journal ...

Gender equality universally linked to physical capacity

Fitness among young adults varies widely from one country to another, and is strongly associated with both socioeconomic development and gender equality, a new study from Karolinska Institutet published in the Journal of ...

Abnormal cell 'conversations' drive chronic lung-transplant rejection, research reveals

More than 50% of lung-transplant recipients experience a rejection of their new lung within five years of receiving it, yet the reason why this is such a prevalent complication has remained a medical mystery.

Fewer women receive lung transplants despite policy changes, study finds

New research from UCLA Health reveals that women continue to face barriers in accessing lung transplants compared to men, despite recent national policy changes aimed at making organ distribution more equitable.

How is radiation therapy portrayed in art?

Because patient perceptions of radiation can influence their willingness to receive it as treatment, researchers recently examined how radiation therapy is represented in different forms of art.

Infrared sauna may hold benefits for team-sport athletes

A study conducted by the Faculty of Sport and Health Sciences at the University of Jyväskylä, Finland, suggests that using an infrared sauna after exercise can speed up recovery and support performance in team-sport athletes. ...

LeBron James will be the first NBA player to reach 23 seasons. How is he still one of the best?

A common saying in sport is: "Father Time is undefeated."

Physical activity raises daily calorie burn without conserving energy used elsewhere, study finds

The effects of physical activity don't stop when the movement does. In a new study published in the Proceedings of the National Academy of Sciences, Virginia Tech researchers, in collaboration with researchers at the University ...

Rising demands, rising performance: Australian Football League Women's players push limits in finals season

As the Australian Football League Women's (AFLW) finals edge closer, players across the league are preparing to push their limits. Now, new research from the University of South Australia shows that AFLW players are pushing ...

Minimally invasive surgery may improve outcomes in severe stroke

Minimally invasive endoscopic surgery may be an effective and safe treatment for patients with intracerebral hemorrhage, the most severe type of stroke, according to results from a recent clinical trial published in JAMA ...

Could your walk be a signal about your ability to win a fight?

Humans have been fighting each other since the earliest stages of our species' history.

Built-in backup system helps muscles counteract fatigue

When you're running up stairs or out on a jog, your muscles eventually start to feel heavy and weak. That's fatigue setting in, a sign that the muscles' energy reserves are becoming depleted. But a team of researchers led ...

GPS technology reveals that football practices can be up to 40% more demanding than games

Until recently, there has been little data available on how much effort football players exert in games versus practices, which position groups run the most or how to balance loads in practice to best meet the needs of game ...

The exercise paradox: Why workouts aren't great for weight loss but useful for maintaining a healthy body weight

The basic principle of weight loss is straightforward: if you consume fewer calories than you burn, you'll lose weight. In practice though, this isn't usually so easy or simple.

Recommended News For You

One possible target in acute myeloid leukemia is the reductive carboxylation of glutamine.

Oleanolic acid from grapes may increase chemotherapy effectiveness

Patients value communication skills from cancer surgeons across six key areas, according to research

Year in Review: Multiple Myeloma

Significant worldwide disparities seen in availability and timeliness of new cancer drugs

In KRAS-mutated non-small cell lung cancer, glecirasib exhibits promising efficacy.

New Zealand and Australian breast cancer rates among the highest in the world, global study finds

Recommended Articles For You

Leukemia in Focus: Tools, Trials, and Therapy Strategies for Modern Medical Practice 

Lentigo Maligna Melanoma: Everything You Need To Know about This Skin Cancer 

Chloride Test in HCC: Diagnostic Utility, Prognostic Role, and Emerging Insights 

Unveiling Canine Blood Clots Over Time: A Look at Low-Field MRI's Diagnostic Potential 

Whats more on Hidoc Dr.

Medical Updates
KOL Videos
Surveys
Events

Daily news to keep you up to date

Gain valuable insights with our in-depth KOL Video discussions

Participate and win cash vouchers

Get updates on the latest events happening around the world
Featured News
Featured Articles
Featured Events
Featured KOL Videos

1.

GuCS Future Focus: Future Focus from the Genitourinary Cancers Symposium

2.

The main subject is associated with suicide in the United States.

3.

Alkem introduces cetuximab under the trade name Cetuxa in India.

4.

Firefighters who eat better can combat cancer.

5.

How scientists are hacking bacteria to treat cancer, self-destruct, then vanish without a trace

1.

Digital Oncology: How Remote Monitoring and Mobile Health Are Transforming Cancer Care

2.

Progressive Insights in Hematology in the Digital Era

3.

Clinical Decision-Making in Oligometastatic Cancer: A Case-Based Perspective

4.

Advancing Oncology Careers with Education, Workflow Tools, and Clinical Resources

5.

The Rise of Immunotherapy: New Advances in Cancer Treatment

1.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

2.

International Cancer Conference

3.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

4.

Asian Symposium on Advancement in Hematology and Oncology

5.

Asian Symposium on Advancement in Hematology and Oncology

1.

Unmet Needs in ALK Positive NSCLC- The Challenges in the Current Care

2.

Blood Clotting Disorders Explained

3.

Sickle Cell Disease Explained

4.

Influence of CDK4/6 Inhibitors in Extending Progression-Free Survival (PFS) and Overall Survival in HR+/HER2- mBC Patients

5.

Pazopanib: A Game-Changer in Managing Advanced Renal Cell Carcinoma - Part II

Fastest Growing Medical Platform for Doctors

Address :
Hidoc Dr. Inc. | Delaware C Corp | 1309 Coffeen Ave. Suite 1200, Sheridan WY, 82801

Phone :
+1-415-463-3094

Email :
anishagadia@hidoc.co

Quick Links

Drug DatabaseDrug InteractionDiseases Database
KOL VideosKnowledge HubQuizzes
Medical UpdatesEventsAbout Us

© Copyright 2026 Hidoc Dr. Inc.

Terms & Conditions - LLP | Inc. | Privacy Policy - LLP | Inc. | Account Deactivation
Home
Profile
Login
bot