Lipid Guidelines: Four Major Concerns

Published Date: 15 May 2026

Too many Class I recommendations lacking supporting data from randomized trials and intellectual conflicts of interest are among John Mandrola’s complaints about the ACC/AHA guidelines on dyslipidemia.

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Rare squamous transformation in metastatic prostate cancer caused disease progression despite suppressed PSA, found only through re-biopsy.

No dose of alcohol is risk-free, and none protects the heart. It's time to counsel patients on drinking less rather than where the line sits.

A woman receiving ruxolitinib for polycythemia vera developed disseminated tuberculosis despite a negative IGRA, highlighting the limits of screening.

From nutrition screening to IBD monitoring, AI shows promise in pediatric gastroenterology — yet experts stress pediatric validation is essential.

Four cases highlight the aggressive nature of cutaneous squamous cell carcinoma arising in chronic perianal and gluteal hidradenitis suppurativa.

A monthly snapshot of FDA activity involving therapies used in the prevention, diagnosis, and treatment of neurologic conditions.

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