MR Metformin and SGLT2i Now First-Line in Type 2 Diabetes

Published Date: 27 May 2026

Clinicians at the Primary Care Show discuss what revised NICE guidance means for type 2 diabetes management in practice.

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Todays Updates

HIV Care Coordination Program May Reduce Deaths in NYC

New York City’s revised Care Coordination Program may help reduce risks for all-cause and HIV-related deaths among people with HIV infection, including those at the highest risk for poor outcomes.

Teplizumab Approved for Pediatric Stage 3 Type 1 Diabetes

The drug was previously approved for stage 2 T1D.

One in Four Teen Girls and Young Women at Risk for PMOS

Findings suggest young females should be assessed and, if at risk, monitored.

Palopegteriparatide Benefits Sustained Beyond 3 Years

Final results from the PaTHway trial show the long-acting parathyroid hormone therapy enabled patients with hypoparathyroidism to achieve independence from high-dose calcium and vitamin D supplements.

Testosterone Prescribing Often Ignores Guidelines

Only 12% of patients prescribed testosterone underwent appropriate diagnostic testing, and overprescribing was common in a single-center US study.

Encaleret Shows Rapid Response in ADH1

The oral modulator of the calcium-sensing receptor targets the causes of ADH1, significantly improving serum and urine calcium levels.

Off-Label Rxs: Thinking Out of the Box for Skin Diseases

Off-label alternatives for FDA-approved therapies can be as effective, cheaper, and in some cases safer despite never having been submitted for regulatory approval.

Latest News

Insights on the relationship between LDH and clinical outcomes from the GALACTIC-HF, a phase 3, randomized, placebo-controlled trial evaluating omecamtiv mecarbil in HFrEF.

The in-home, patient-friendly peripheral arterial tonometry test seems to be the wave of the future for diagnosing obstructive sleep apnea. Dr Aaron Holley discusses this wearable device known as PAT.

The National Institutes of Health appointed Dr. John Powers III as ⁠acting director of its infectious disease institute, the agency's website showed on...

Experts highlight clues that help identify drug-induced alopecia and outline treatment strategies tailored to the underlying mechanism and pattern of hair loss.

Reversing cellular age isn’t science fiction, but the biology is more complicated than either the skeptics or the hype artists want to admit.

Latin America continues to lag the global decline in HIV-related mortality, prompting experts to identify research priorities targeting advanced HIV and gaps in care.

News All Time

Visible Light and Skin Health: What Clinicians Should Know

An international expert panel issues consensus recommendations on visible light photoprotection, highlighting its emerging role in skin health and disease.

Several Markers May Flag Severity of Peanut Allergy in Kids

Several biomarker measures such as wheal diameters on skin prick tests, peanut-specific antibody levels, and basophil activation differ between children with severe vs mild reactions to peanuts.

MHRA Approves Nipocalimab for Myasthenia Gravis

The MHRA has authorised nipocalimab for generalised myasthenia gravis in adults and adolescents aged 12 and over, based on evidence from two clinical studies.

WHO's Tedros Says Uganda Should Reconsider Congo Border Closure Over Ebola

The director-general of the World Health Organization said on Monday ⁠that Uganda should reconsider its decision to close its border with Democratic ⁠Republic of Congo...

AI Brings Oxygen Therapy Closer to Autopilot

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Ontario Researchers Discover Promising Antibiotic

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TNFi Use in Early Peripheral SpA Outperforms Methotrexate

‘These data [from the phase 3 SPARTACUS trial] support the importance of early diagnosis and early treatment before structural damage,’ said one expert not involved in the research.

Lyme Primer: How the HHS Strategy Stacks Up To Science

Experts support targeting ticks but caution against the long-term use of antibiotics.

FDA Approves First New Sunscreen Option in Two Decades

Bemotrizinol protects against both ultraviolet A and B rays, has low absorption through the skin, and is safe for adults and children 6 months and older, according to the FDA.

US Adds $38 Million for Ebola as CDC Warns Outbreak Could Match 2014

The United States said on Friday it would provide an additional $38 million for Ebola response efforts, as the CDC warned that without strong public health interventions the...

Whole Blood vs Components: No Survival Benefit in Trauma

Prehospital transfusion with whole blood was not linked to reduced 30-day mortality compared with prehospital transfusion with blood components in patients with traumatic hemorrhage, a phase 3 trial finds.

New POCUS for Residents: Should Hospitalists Join?

Few attending hospitalists have formal training in point-of-care ultrasound, but more are eager to learn.

Hospitalists Leading Health Informatics in the Digital Age

Technology in hospitals is changing quickly, having clinicians at the helm makes a difference.

Health Experts to Screen US Wastewater for Disease Outbreaks During World Cup

Epidemiologists will be busy this summer sifting through sewage and social media with the goal of keeping soccer fans and the public safe from severe illness during the...

'They're Betting Our Herd': Texas Ranchers Question USDA as Screwworm Returns

Like many ranchers in South Texas, Susan Storey said nightmarish screwworm outbreaks were among her first childhood memories. Now 62, she still recalls seeing wriggling...

Oral Glucocorticoids Linked to Higher Candidemia Risk

The use of oral glucocorticoids increases the odds of developing candidemia in a dose-dependent fashion; effects are strongest in users with inflammatory bowel disease.

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