Gene expression signatures indicate a loss of function by major genome regulators

Published Date: 12 Apr 2023

Second only to the notorious TP53 gene, assemblage genes, known as MSWI/SNF protein complexes, are the most commonly mutated formations in cancer cells. The complexes, consisting of 10-15 units, are built from...

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Trappsol Cyclo Misses Primary End Point in Phase 3 Trial for Niemann-Pick Disease Type C Isabella Ciccone, MPH

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Latest News

In a surprising discovery, a "sticky molecule" that occurs naturally in our blood vessels could be both a culprit behind blood clots and organ failure during COVID and long COVID and the key to new treatments to counter COVID-related ...

A new discovery from the lab of YouYang Zhao, Ph.D., from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago, opens promising new directions for treatment of life-threatening ...

Genetic susceptibility to neurodevelopmental conditions such as schizophrenia, autism, and ADHD can be linked, in part, to distinct epigenetic signatures in newborn cord blood. An analysis of nearly 6,000 newborns published ...

In a major step forward for cancer care, researchers at ChristianaCare's Gene Editing Institute have shown that disabling the NRF2 gene with CRISPR technology can reverse chemotherapy resistance in lung cancer. The approach ...

Mice pups conceived with in vitro fertilization (IVF) in the lab have slightly increased rates of DNA errors, or mutations, compared to pups conceived naturally, a new study on artificial reproductive technologies suggests.

Researchers have identified that the precisely timed transcription of two genes named grim and reaper is responsible for the targeted death of neurons within the developing nervous system of female flies. This group of neurons ...

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Surprising blood stem cell diversification revealed in humans

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Hundreds of genes act differently in the brains of men and women

Differences between men and women in intelligence and behavior have been proposed and disputed for decades.

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Study identifies key genes linked to aggressive prostate cancer in people of African descent

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Experimental drug blocks key protein to trigger cancer cell self-destruction in lung tumors

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Hidden nuclear droplets link multiple leukemias and reveal a new therapeutic target

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