SGLT2 Inhibitors: Real-world data shows overwhelming benefits and risks.

Published Date: 01 Apr 2023

The use of SGLT2 inhibitors has been associated with reduced rates of low frequency and bone loss in patients with CKD and type 2 diabetes in the United States, which is more surprising than dangerous.

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Latest News

A new study underscores the importance of monitoring patients’ cardiometabolic health soon after starting ADT plus ARPI therapy for prostate cancer.

A lesion network analysis reveals cerebellar and occipital regions consistently associated with dizziness after ischemic stroke, regardless of lesion location or symptom subtype.

Women make up less than 10% of oversight committee seats for interventional structural heart disease trials, although women are being studied more intently than ever before.

AI-powered stethoscopes are showing promise in primary care, with new evidence suggesting improved detection of heart failure, atrial fibrillation, and valvular disease.

Non-vitamin K oral anticoagulant use was associated with modestly slower cognitive decline and lower risks for death and stroke in adults with comorbid Alzheimer’s disease and atrial fibrillation.

Patients with acromegaly-associated diabetes face a higher risk for cardiovascular morbidity, but not mortality, than those with type 2 diabetes.

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Photon-Counting CT Boosts Stent Fracture Detection

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Postpartum Health Coaching Boosts Blood Pressure Control

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Central Adiposity May Reclassify CVD Risk Beyond BMI

Among individuals with normal BMI, elevated waist circumference or waist-to-hip ratio may identify cardiovascular risk beyond BMI.

Allopurinol Offers No Heart Benefit in Kidney Donors

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Quarter of Gestational Diabetes Moms Get Early Hypertension

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Cardiometabolic Index Can Predict Mortality Risk in T2D

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Three Midlife Risk Factors Linked to Earlier Dementia Onset

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Even Low Physical Activity May Lower Stroke Risk in AF

Even low levels of physical activity were linked to lower stroke and mortality risks in atrial fibrillation, with greater benefits generally seen at higher activity levels.

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In patients with ischaemic stroke, intravenous thrombolysis given within 90 minutes of symptom onset improves functional outcomes, but the benefit fades progressively beyond this window.

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Children with obesity who exhibit more dynamic movement patterns and less sedentary accumulation show better insulin sensitivity and body composition.

Body Fat Patterns Show Similar T2D Predictive Value

Traditional and newer adiposity measures both moderately predict 20-year diabetes risk in healthy adults, yet dysfunctional tissue markers are slightly better at predicting future cases.

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