Baricitinib Misses Key Safety Benchmark in High-Risk RA

Published Date: 08 Jun 2026

Patients with RA have a higher risk of blood clots and serious infections with baricitinib vs older biologics, but not heart disease or cancer, according to two safety trials.

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When It’s Really Hot: What Mental Health Risks Are Missed?

Extreme heat can worsen psychiatric symptoms and disrupt sleep, whereas some medications may increase vulnerability to dehydration, heat illness, and toxicity.

ANCA Vasculitides Tied to Higher Cardiovascular Event Risk

Both granulomatosis with polyangiitis and microscopic polyangiitis are associated with an increased risk for cardiovascular and thromboembolic events.

Metabolic Conditions Common in Chronic Rhinosinusitis

Overweight or obesity, hypertension, and diabetes are common in patients with chronic rhinosinusitis, but their prevalence is similar to global reference estimates, a meta-analysis finds.

Health Rounds: AstraZeneca Drug Reduces Lung Disease Flare-ups in Late-stage Trials

(This is an excerpt of the Health Rounds newsletter, where we present latest medical studies on Tuesdays and Thursdays.)

NHS Urged to Scrap 'Outdated' Transplant Rule

Blood cancer charities want NHS England’s blanket rule on second stem cell transplants changed to reflect modern practice and opinion.

Horse Smuggling Exposes Cracks in US Defenses Against Screwworm

When sheriff's deputies intercepted a trailer carrying six horses near the border town of Redford, Texas, they uncovered more than a livestock violation. The animals had...

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Sevabertinib Approved for First-Line Mutated NSCLC

The oral HER2 TKI was previously given accelerated approval in the second line for the indication.

Todays Updates

Sevabertinib Approved for First-Line Mutated NSCLC

The oral HER2 TKI was previously given accelerated approval in the second line for the indication.

Latest News

Extreme heat can worsen psychiatric symptoms and disrupt sleep, whereas some medications may increase vulnerability to dehydration, heat illness, and toxicity.

Both granulomatosis with polyangiitis and microscopic polyangiitis are associated with an increased risk for cardiovascular and thromboembolic events.

Overweight or obesity, hypertension, and diabetes are common in patients with chronic rhinosinusitis, but their prevalence is similar to global reference estimates, a meta-analysis finds.

(This is an excerpt of the Health Rounds newsletter, where we present latest medical studies on Tuesdays and Thursdays.)

Blood cancer charities want NHS England’s blanket rule on second stem cell transplants changed to reflect modern practice and opinion.

When sheriff's deputies intercepted a trailer carrying six horses near the border town of Redford, Texas, they uncovered more than a livestock violation. The animals had...

News All Time

1 in 5 Patients With Bacteremia Have Skin Involvement

Skin involvement is common in neutropenic patients with a Pseudomonas aeruginosa bloodstream infection, a study suggests.

Cancer Risk Low, Similar Across IBD Advanced Therapy Classes

Patients with IBD face similar risk for cancer whether treated with TNF antagonists, vedolizumab, anti-interleukins, or JAK inhibitors, with overall incidence remaining low across all therapy classes.

MMR Deficiency Tied to Better Survival in Gastric Cancer

Patients with mismatch repair-deficient oesophagogastric adenocarcinoma treated with perioperative chemotherapy show significantly improved survival outcomes.

e-Cigarettes May Increase Risk for RA or SLE

Current e-cigarette users face a higher risk of developing incident rheumatoid arthritis or systemic lupus erythematosus than nonusers, a study finds.

How an Old Antibiotic Can Kill a Drug-Resistant Superbug

Researchers using "click chemistry" disabled a superbug's defenses against a classic antibiotic, potentially finding a way to solve antibiotic-resistant bacteria.

Salmonella Cases Top 500 in Outbreak Linked to Imported Eggs

The UKHSA says the outbreak now spans three genetically distinct Salmonella clusters, but the risk to the public remains low.

Rebel-held Eastern Congo Records New Ebola Case After Declaring Outbreak Over

A new Ebola case has been recorded in an area controlled by ⁠AFC/M23 rebels in eastern Congo, the group said, more than two months after it declared ⁠the outbreak over in...

5 Things Doctors Should Know About Medical AI Regulation

Federal and state regulators are drawing new boundaries around medical AI, from how the tools are vetted to who bears responsibility when they fail.

AI Speeds Up Chest Radiograph Readings but Lowers Accuracy

Commercial AI tools for chest radiography reduce reading time and boost reader confidence but fail to improve diagnostic accuracy.

Sequencing of TAVI Before PCI Found to be Noninferior

Although percutaneous intervention for coronary artery disease is commonly performed before transcatheter aortic valve implantation in those who need both, a trial supports either sequence.

5 Ways to Spot Sepsis Before It’s Too Late

A patient who seems ‘just a little sick’ may be far more ill than they appear. These signs can help clinicians spot sepsis sooner.

Second RSV Dose Recommended for Some Kids

The updated recommendations reflect a growing consensus among medical organizations that a second-dose RSV vaccine can provide additional protection.
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Skin Deep: Could Clues Reveal Underlying Disease Early?

From liver disease to malignancy, characteristic skin findings can prompt a broader evaluation and help physicians consider systemic conditions during routine examinations.
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