Digestive enzyme leakage from gut to organs may cause aging in rats

Published Date: 30 Oct 2024

The mucosal layer in the small intestine degrades with age in rats, allowing digestive enzymes to slowly escape and leak into organs outside the intestine, including the liver, lung, heart, kidney and brain.

Read Full News

Latest News

Green Giant: How Taylor Farms Became a Top Salad Supplier Before US Diarrhea Outbreak

Taylor Farms, the produce supplier at the center of the massive U.S. cyclosporiasis outbreak, changed the way that America eats after launching branded, prepackaged and...

Cyclosporiasis Cases in US Climb to 15,716, CDC Says

The Centers for Disease Control and Prevention on Tuesday reported 15,716 confirmed cases of ⁠cyclosporiasis in the United States, an increase of 1,821 cases from a week...

Quebec Opposes Lowering Colorectal Cancer Screening Age

Quebec’s health ministry is opposing experts’ recommendation to lower the colorectal cancer screening age to 45 years.

Colon Capsule Endoscopy: Why It Fails

In colon capsule endoscopy, chronic opioid use is linked to incomplete examinations and inadequate bowel preparation, whereas diabetes is tied to poorer bowel preparation.

Can Steroids Reduce Complications of GI Surgeries?

Researchers randomized about 1200 patients undergoing elective surgery for digestive cancer to receive either methylprednisolone or placebo at anesthesia induction.

Is the Combination of GLP-1s and Clozapine Safe?

Gastrointestinal hypomotility is the most lethal adverse event linked to clozapine use. GLP-1s slow the gut too. Clinicians are combining the two, with little safety data to guide them.

Todays Updates

Hyponatremia Risk Varies Among Second-Gen Antipsychotics

Aripiprazole is associated with a lower risk for hyponatremia compared with olanzapine in patients treated with second-generation antipsychotics, a new cohort study shows.

HCT Survival Outcomes Improving in Relapsed Hodgkin Lymphoma

Researchers evaluate changes in post-transplantation outcomes among patients with relapsed or refractory Hodgkin lymphoma from 2010 to 2022.

How Much of a Cancer Drug Is Too Much?

In a recent KFF survey, 43% of US adults said they had skipped their medication in the past year because of cost.

Todays Updates

Hyponatremia Risk Varies Among Second-Gen Antipsychotics

Aripiprazole is associated with a lower risk for hyponatremia compared with olanzapine in patients treated with second-generation antipsychotics, a new cohort study shows.

HCT Survival Outcomes Improving in Relapsed Hodgkin Lymphoma

Researchers evaluate changes in post-transplantation outcomes among patients with relapsed or refractory Hodgkin lymphoma from 2010 to 2022.

How Much of a Cancer Drug Is Too Much?

In a recent KFF survey, 43% of US adults said they had skipped their medication in the past year because of cost.

Latest News

Taylor Farms, the produce supplier at the center of the massive U.S. cyclosporiasis outbreak, changed the way that America eats after launching branded, prepackaged and...

The Centers for Disease Control and Prevention on Tuesday reported 15,716 confirmed cases of ⁠cyclosporiasis in the United States, an increase of 1,821 cases from a week...

Quebec’s health ministry is opposing experts’ recommendation to lower the colorectal cancer screening age to 45 years.

In colon capsule endoscopy, chronic opioid use is linked to incomplete examinations and inadequate bowel preparation, whereas diabetes is tied to poorer bowel preparation.

Researchers randomized about 1200 patients undergoing elective surgery for digestive cancer to receive either methylprednisolone or placebo at anesthesia induction.

Gastrointestinal hypomotility is the most lethal adverse event linked to clozapine use. GLP-1s slow the gut too. Clinicians are combining the two, with little safety data to guide them.

News All Time

Acting US FDA Chief Urges Confidence in Lettuce as Agency Updates Produce Safety Guidance

Acting U.S. FDA Commissioner Kyle Diamantas said on Tuesday Americans should feel confident in eating fresh produce, as the agency has finalized guidance for proper...

Listeriosis Incidence Stable Despite Aging Population

The incidence of invasive listeriosis has remained stable in the US from 2008 to 2023, although certain groups face disproportionately higher rates.

‘Concerning’ Trends in Cancer Drug Approvals

FDA approvals for solid tumor drugs increasingly rely on response rates as the primary evidence supporting approval rather than overall survival.

What to Know About the Multistate Salmonella Outbreak in the US

(Removes abbreviation in paragraph 2 and makes 'salmonella' lowercase throughout)

US FDA to Hold Advisory Meeting to Review Grail's Multi-cancer Test

Grail said on Friday the U.S. FDA plans to hold a meeting of outside experts to review its multi-cancer screening test ⁠Galleri in September, sending its shares up...

US Cyclosporiasis Probe Linked to Lettuce Widens to 15 States

U.S. health authorities have widened their probe into a cyclosporiasis outbreak tied to iceberg lettuce from central Mexico after detecting cases in six additional states,...

Mexican Jalapenos Tied to Salmonella Outbreak in 27 US States

U.S. health officials are investigating a Salmonella outbreak linked to Mexican jalapeno peppers that has sickened 345 people in 27 states, prompting supplier ⁠Coast Citrus...

Genetic Marker Linked to Severe Outcomes Across IBD Subtypes

HLA-DRB1*01:03 may serve as a genetic marker for severe outcomes across IBD phenotypes and help identify patients at higher risks for surgery and treatment failure.

Does High-Dose Vitamin D3 Supplementation Improve CRC Survival?

A phase 3 trial was conducted to confirm the benefit of high-dose vitamin D3 supplementation in patients with previously untreated metastatic CRC that was seen in a phase 2 trial.

IV Vitamin C With Chemo Shows Signals in Cancer Care

A phase 2 study reported a longer median overall survival in patients receiving IV ascorbate with chemotherapy, although larger randomized trials are needed to confirm the finding.

Small Colorectal Lesions Carry Risk for Deep Invasion

Non-pedunculated colorectal lesions smaller than 2 cm may harbor deep submucosal invasion despite their diminutive size, study finds.

Etrasimod Effective As First-Line Advanced UC Therapy

Etrasimod can be an effective and safe first-line advanced therapy option in patients with ulcerative colitis who escalate after conventional treatment failure.

Does Doublet Chemotherapy Improve Survival in Rectal Cancer?

Patients with high-risk locally advanced rectal cancer were randomly assigned to receive doublet-LC TNT or conventional neoadjuvant chemoradiotherapy.

Radiation Boost Linked to Better Survival in Rectal Cancer

A phase 2 trial finds that adding a modest radiation boost improves 9-year survival without increasing toxicity, despite no improvement in pathologic complete response.

Creatinine Assay Bias Affects MELD Scoring

Bilirubin interference in commonly used creatinine assays artificially inflates MELD scores in liver transplant candidates, a study reports.

EHR Marker May Help Curb Risk for Liver Transplant Rejection

A remote intervention aimed at improving medication adherence may reduce organ rejection in liver transplant recipients at high risk.

Recommended News For You

AI Breath Test IDs Cancers; More Grief for Prior Auth; Imatinib Discoverer Resigns

Sickle Cell Disease Drug Pulled From Global Markets

After two years, a significant left nasal obstruction was finally diagnosed.

Axatilimab Demonstrates Effectiveness in Refractory/Recurrent GVHD.

Glioblastoma cells can 'unstick' from their neighbors to become more deadly

Anticoagulation for 12 months has been found to improve outcomes in cancer patients with minor blood clots.

enhancing survivors of brain tumors' quality of life.

Recommended Articles For You

Strategic Standards in Hematology for Specialists 

Metabolic Vulnerabilities in Solid Tumor Progression 

Revolutionizing Cancer Treatment: Harnessing the Power of AI in Histopathology 

Understanding Melanoma: From Diagnosis to Healing and Excision in Denver 

Whats more on Hidoc Dr.

Medical Updates
KOL Videos
Surveys
Events

Daily news to keep you up to date

Gain valuable insights with our in-depth KOL Video discussions

Participate and win cash vouchers

Get updates on the latest events happening around the world
Featured News
Featured Articles
Featured Events
Featured KOL Videos

1.

Q&A: When will individuals be able to receive customized cancer vaccines?

2.

Canadian Group Calls for Earlier Colorectal Cancer Screening

3.

Children living near oil and gas wells face higher risk of rare leukemia, studies show

4.

Researchers achieve a significant milestone in the management of anemia in chronic lymphocytic leukemia.

5.

Talquetamab Combos Show Survival Benefit in r/r Myeloma

1.

Liquid Biopsy: A Revolutionary Tool for Early Detection and Monitoring of Colorectal Cancer

2.

Clinical Pharmacology of Megakaryocyte Maturation-Targeted Therapeutics

3.

The Benefits and Side Effects of Bortezomib in the Fight Against Cancer 

4.

Personalized Tumor Ecological Landscapes in Oncology

5.

Unmasking the Subtle Symptoms of Colon Cancer

1.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

2.

International Cancer Conference

3.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

4.

Asian Symposium on Advancement in Hematology and Oncology

5.

Asian Symposium on Advancement in Hematology and Oncology

1.

Lorlatinib in the Management of 1st line ALK+ mNSCLC (CROWN TRIAL Update)

2.

Pazopanib Takes Center Stage in Managing Renal Cell Carcinoma - Part II

3.

Current Scenario of Cancer- Q&A Session to Close the Gap Part II

4.

Cost Burden/ Burden of Hospitalization For R/R ALL Patients

5.

Immunotherapy: A New Era in Cancer Treatment

Fastest Growing Medical Platform for Doctors

Address :
Hidoc Dr. Inc. | Delaware C Corp | 1309 Coffeen Ave. Suite 1200, Sheridan WY, 82801

Phone :
+1-415-463-3094

Email :
anishagadia@hidoc.co

Quick Links

Drug DatabaseDrug InteractionDiseases Database
KOL VideosKnowledge HubQuizzes
Medical UpdatesEventsAbout Us

© Copyright 2026 Hidoc Dr. Inc.

Terms & Conditions - LLP | Inc. | Privacy Policy - LLP | Inc. | Account Deactivation
Home
Profile
Login
bot