What’s at Issue in the FDA’s Request to Withdraw Avacopan?

Published Date: 24 Feb 2026

European regulators are also conducting a review of avacopan. The issue appears to involve data from the pivotal ADVOCATE trial and questions of liver safety.

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Hyponatraemia during the first 72 hours of life is linked to later neurodevelopmental disorders or death in infants with perinatal asphyxia.

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