Confusion and Clarity Regarding the Serotonin Hypothesis in Depression.

Published Date: 06 May 2023

Dr. Drew Ramsey and J. Dr. John Mann talks about the serotonin theory of depression.

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Age-Specific Needs in Young Women With Breast Cancer

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Amantadine Awakens 94-Year-Old Woman After Stroke

A short amantadine course produced eye opening and tracking within 24 hours and a GCS of 14-15 by day 4 in a case of prolonged nontraumatic impaired consciousness.

Advances in Chronic Rhinosinusitis From ARS 2026

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May 15 2026 This Week in Cardiology

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Inside OCT and IVUS: AI’s New Edge in PCI

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Datopotamab Deruxtecan Earns New Breast Cancer Indication

The antibody drug conjugate was approved by the FDA for certain patients with triple-negative breast cancer.

Todays Updates

EMA Backs Breast Cancer SERD After FDA No Vote

The recommendation follows phase 3 data showing longer progression-free survival when patients switched to camizestrant plus a CDK4/6 inhibitor.

Datopotamab Deruxtecan Earns New Breast Cancer Indication

The antibody drug conjugate was approved by the FDA for certain patients with triple-negative breast cancer.

Latest News

Drs Olivia Pagani and Ann Partridge discuss how to optimize the care plan for young patients with breast cancer, focusing on age-specific concerns such as fertility and long-term survivorship.

A short amantadine course produced eye opening and tracking within 24 hours and a GCS of 14-15 by day 4 in a case of prolonged nontraumatic impaired consciousness.

Advances in chronic rhinosinusitis from ARS 2026 include data on biologics vs surgery rates, AI tools in clinic, and wearable tech to document clinical efficacy, as reported by Dr Vijay Ramakrishnan.

Dr Bora Lim anticipates new data on bispecific antibodies and CDK4 inhibitors, as well as crucial updates on ADCs and ctDNA-guided treatments.

Another positive digoxin trial, another classic coronary physiology study from Imperial College London (ORBITA-FIRE), news in hypertrophic cardiomyopathy, and TAVR done in the wrong patients are the topics John Mandrola, MD, discusses in this week’s podcast.

From automatic calcium and lipid detection to post-stent expansion checks, learn how AI helps close the gap between novice and expert and why that matters for outcomes.

News All Time

Beware of Radiation Doses Among Heart Scanners, Study Says

Coronary CT angiography, poorer countries under scrutiny for larger doses

Reining in Overdiagnosis of Papillary Thyroid Cancer: Easier Said Than Done

Cutting ultrasound referrals for nonpalpable nodules could lead to decreases in incidence

Should We Do a Shoulder MRI? Food Prescriptions for Diabetes

Also in TTHealthWatch: a planetary health diet, and patient views of statin therapy

Lead Suits Cut Physician Radiation Exposure for Interventional Cardiology Cases

Median exposure reduced to 0 versus lead apron during LAAO, with possible broader applicability

Routine Mammograms That Also Flag CVD: Two Birds With One Stone?

AI-driven quantification of breast arterial calcification on imaging could ID higher-risk women

Even Patients Are Shocked by the Prices Their Insurers Will Pay

And it costs all of us

Tiny Blood Smidges in the Brain: Amount and Location Tied to Dementia

Neuroimaging findings believed to arise from distinct pathologies

Deepfake X-Rays Sneak Past Radiologists and AI, Underscoring Abuse Potential

Unaware they were looking at phony images, a majority of radiologists judged fakes as real

Ultrasound Treatment for Prostate Cancer Has Early Advantage Versus Prostatectomy

Better continence, erectile function, but data on oncologic outcomes still 2 years away

AI Strategy Could Eliminate Radiologist Review of Low-Risk Mammograms

Approach cut workload by 64% and increased cancer detection rate versus standard strategy

PSMA-PET Cuts Need for Biopsy in Suspected Prostate Cancer

But does it cost too much?

Quiz Time: Can Radiologists Spot AI Deepfakes?

You passed medical training, now see if you can pass our weekly quiz

Low Breast Cancer Recurrence Rate With Radiotherapy Tailored to Nodal Response

Locoregional recurrence rate of 2.9% overall with no variation across node-defined risk groups

Mammography Use Declined Among Younger Women in Recent Years

Decline follows the 2009 change to USPSTF guidelines for women ages 40 to 49

False-Negative CAC Findings That Equal Zero Cluster in Certain Groups, Study Finds

Race/ethnicity and country important to consider when interpreting coronary artery calcium score

Replace Yourself With AI, CEO Katz

Let's test out this new tech where the downside is a bad spreadsheet, not a missed cancer

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