According to a recent JAMA study, stopping metformin in diabetic patients is associated with an increased risk of dementia.

Published Date: 30 Oct 2023

New research has uncovered an intriguing association between the cessation of metformin treatment for reasons unrelated to kidney dysfunction and the.

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GLP-1s: Continued Use Equals Continued Success

Many adults on GLP-1s maintain their weight loss at 2 years. Full return to baseline weight is found to be rare.

Can Eating Tomatoes Reduce Liver Fat in Adults With MASLD?

Daily consumption of tomatoes and tomato sauce seems to reduce hepatic steatosis in adults with MASLD.

Excess Pancreatic Fat Tied to Elevated Mortality Risk

Excess fat deposition in the pancreas is linked to an increased risk for all-cause mortality, particularly from vascular causes, in the general population.

Does GIP Provide Added Glycemic Benefit in T2D?

When added to semaglutide or placebo, glucose-dependent insulinotropic polypeptide (GIP) shows no effect on glycemic control in type 2 diabetes.

Adrenal Incidentalomas: Repeat Testing May Inform Management

About one1 in five5 patients with adrenal incidentalomas hadve changes in cortisol status over time, suggesting that routine repeat testing may influence management in selected patients.

Novo Begins Study to Find Lowest Effective Dose for Wegovy Pill

Danish drugmaker Novo Nordisk is testing smaller doses of its Wegovy pill in a new late-stage study to find the lowest ⁠dose that would still help patients lose weight,...

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Early Breast Cancer: Time to Act on Molecular Resistance?

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Punch Biopsy Techniques Every PCP Should Know

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Medicare Is Paying Less for Cataract Surgery

Medicare pays doctors about $520 for a standard cataract procedure, down about 20% in the past decade.

Congo Set to Receive 70,000 Ervebo Vaccines to Contain Ebola Outbreak, WHO Says

The Democratic Republic of Congo has been allocated 70,000 doses of Merck's Ervebo vaccine for Ebola, the World Health ⁠Organization said on Thursday, as the country...

Lenacapavir PrEP: No New HIV infections & High Satisfaction

Participants in the PURPOSE 1 trial particularly appreciated the convenience of not needing a daily pill and the confidence of feeling protected from HIV long-term.

Green Giant: How Taylor Farms Became a Top Salad Supplier Before US Diarrhea Outbreak

Taylor Farms, the produce supplier at the center of the massive U.S. cyclosporiasis outbreak, changed the way that America eats after launching branded, prepackaged and...

Minor Hallucinations Distinguish Early DLB From AD

Minor hallucinations and pareidolic responses differentiate early dementia with Lewy bodies from AD, a study shows.

Todays Updates

Early Breast Cancer: Time to Act on Molecular Resistance?

In breast cancer, molecular resistance can precede clinical progression, but should it prompt an immediate change in treatment?

Punch Biopsy Techniques Every PCP Should Know

Performing a punch biopsy doesn't have to be daunting. Learn the essential steps every PCP needs to confidently sample, suture, and care for biopsy sites.

Medicare Is Paying Less for Cataract Surgery

Medicare pays doctors about $520 for a standard cataract procedure, down about 20% in the past decade.

Congo Set to Receive 70,000 Ervebo Vaccines to Contain Ebola Outbreak, WHO Says

The Democratic Republic of Congo has been allocated 70,000 doses of Merck's Ervebo vaccine for Ebola, the World Health ⁠Organization said on Thursday, as the country...

Lenacapavir PrEP: No New HIV infections & High Satisfaction

Participants in the PURPOSE 1 trial particularly appreciated the convenience of not needing a daily pill and the confidence of feeling protected from HIV long-term.

Green Giant: How Taylor Farms Became a Top Salad Supplier Before US Diarrhea Outbreak

Taylor Farms, the produce supplier at the center of the massive U.S. cyclosporiasis outbreak, changed the way that America eats after launching branded, prepackaged and...

Minor Hallucinations Distinguish Early DLB From AD

Minor hallucinations and pareidolic responses differentiate early dementia with Lewy bodies from AD, a study shows.

Latest News

Many adults on GLP-1s maintain their weight loss at 2 years. Full return to baseline weight is found to be rare.

Daily consumption of tomatoes and tomato sauce seems to reduce hepatic steatosis in adults with MASLD.

Excess fat deposition in the pancreas is linked to an increased risk for all-cause mortality, particularly from vascular causes, in the general population.

When added to semaglutide or placebo, glucose-dependent insulinotropic polypeptide (GIP) shows no effect on glycemic control in type 2 diabetes.

About one1 in five5 patients with adrenal incidentalomas hadve changes in cortisol status over time, suggesting that routine repeat testing may influence management in selected patients.

Danish drugmaker Novo Nordisk is testing smaller doses of its Wegovy pill in a new late-stage study to find the lowest ⁠dose that would still help patients lose weight,...

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Prader-Willi Experts Flag Safety Risks Linked to Rare Disease Drug

Experts in Prader-Willi Syndrome on Tuesday raised safety concerns over Neurocrine's drug Vykat XR, citing serious adverse events reported ⁠in patients with the rare genetic...

Duration and Age Tied to Different Complication Risks in T1D

In patients with childhood onset T1D, a longer diabetes duration is mainly linked to a higher risk for retinopathy, and older age more strongly predicts albuminuria after over 30 years of follow up.

Weekly Somapacitan Effective and Safe in Turner Syndrome

Once-weekly somapacitan is as effective as daily growth hormone in promoting linear growth among treatment-naive girls with Turner syndrome, offering a suitable alternative treatment.

Role-Play as Patients Helps Docs Manage Diabetes Better

A 1-week, on-site role-play-based program in which physicians simulate patient experiences leads to better A1c control in patients with type 2 diabetes at 6 and 12 months.

Low-Carb Diets: Modest Wins for Weight, Blood Sugar

Cutting carbs may help adults with overweight or obesity achieve modest weight loss and improve some metabolic markers, but the benefits appear limited and don’t increase with stricter restriction.

Med Op-Ed: Drugs, Obesity, and BMI at a Crossroads

Should the FDA rein in celebrity drug endorsements? Could redefining obesity end up rationing care? And is relying on BMI alone letting patients down?

T2D Medication Patterns Vary by A1c Levels

Type 2 diabetes medication adjustments in older adults vary by A1c levels.

US Bars Federal Funding Of Gender-affirming Care for Low-income Minors

The Trump administration finalized a rule on Tuesday barring two major federal health programs from funding puberty blockers, hormone therapy and surgeries to treat gender...

New Obesity Definitions Don’t Improve Liver Risk Prediction

New obesity definitions reclassify 20%-34% of patients with fatty liver disease into the obesity category, but it doesn’t increase their risk for liver-related events.

Harder Calorie Goal Yield More Weight Loss

A harder calorie goal — not a bigger step count, a shorter eating window, or stricter food rules — is associated with greater weight loss in adults with overweight or obesity.

These Two ‘Clock Genes’ May Influence Childhood Obesity

Kids with certain variants in genes regulating sleep and circadian rhythms might be more prone to overeating, new research suggests.

GLP-1s May Reduce Binge Eating

A systematic review and meta-analysis of randomized trials suggests that GLP-1s may reduce binge eating-related behaviors and emotional eating in people with overweight or obesity.

Start Bone-Saving Therapy as Weight Loss Journey Starts

PCPs 'have a duty' to remind patients about bone fragility that may come with weight loss without weight-bearing exercise.

7 Natural Ways to Suppress Appetite Now, and What’s Ahead

A majority of people manage their weight without a prescription drug, and natural strategies to curb appetite can help both them and those on medications.

Can BMI Normalization Reduce Progression to Type 1 Diabetes?

An observational study links BMI normalization to a lower risk for progression to stage 3 type 1 diabetes among autoantibody-positive individuals.

Manufacturing Issues Prevent GEP-NET Radioligand Approval

Maker says it's committed to resolving the issues and remains confident in ¹⁷⁷Lu-edotreotide.

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