C9orf72-ALS and Frontotemporal Dementia Agent WVE-004 is no longer being produced by Wave Life Sciences due to disappointing Phase 1b/2a results.

Published Date: 01 Jun 2023

Key pharmacodynamic biomarker levels were significantly reduced over time, but this did not result in improved function on any of the trial's scales.

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Alzheimer disease and LATE-NC pathology were associated with more timely dementia diagnoses, a study shows.

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