AI-informed approach to CAR design enhances bi-specific CAR T cells

Published Date: 14 Aug 2025

A computational approach by St. Jude Children's Research Hospital scientists promises to make designing T-cell-based immunotherapies that target two cancer-related antigens at the same time far easier and faster.

Read Full News

Latest News

A less invasive, more effective method to analyze immunotherapy efficacy

Immunotherapy has been one of the most promising advancements in cancer treatment. However, consistency in immunotherapy treatment effectiveness remains a formidable challenge. Now, Cancer Center at Illinois member Kun Wang, ...

Immune cell pockets found in lymphoma tumors offer new targets for personalized therapies

By analyzing the tumor environment of diffuse large B-cell lymphoma (DLBCL), researchers from The University of Texas MD Anderson Cancer Center have identified seven distinct cellular microenvironments, providing a framework ...

New genomic test could spare some people with melanoma from lymph node biopsy surgery

A genomic test co-developed by Mayo Clinic and SkylineDx can identify whether people with melanoma are at low or high risk for cancer in their lymph nodes—a finding that could guide treatment decisions and help many people ...

Existing drugs for tissue scarring could help avert melanoma relapses

Cellular changes that appear during melanoma and lead to treatment resistance can be reversed with drugs—potentially opening the door to new or more effective treatments for the deadly disease, according to new Cornell ...

Elironrasib may overcome resistance to prior KRAS G12C inhibition in non-small cell lung cancer

Elironrasib led to meaningful and durable responses in patients with metastatic KRAS G12C-mutated non-small cell lung cancer (NSCLC), including after prior treatment with KRAS G12C inhibitors and in the presence of features ...

Zenocutuzumab shows clinical benefit in rare bile duct cancer

Zenocutuzumab (Bizengri), a bispecific antibody that targets human epidermal growth factor receptor 2 (HER2) and HER3, led to responses in more than a third of patients with neuregulin 1 (NRG1)-positive cholangiocarcinoma, ...

Todays Updates

Many patients learn they could have cancer in the emergency department

Abdominal and chest pain. Injuries. Breathing difficulty. Infections. Mental health emergencies. Those are some of the most common reasons why people go to the local emergency department.

An understudied type of breast cancer poses a lurking threat

University of Colorado Cancer Center member Matthew Sikora, Ph.D., is a national leader in research into an understudied subtype of breast cancer that's on the rise in American women, is often more difficult to detect than ...

How a new light-based cancer treatment could destroy tumors without harming healthy cells—using LEDs

Cancer treatment has come a long way, but many of today's therapies still come with steep costs: not just financial, but physical and emotional too. Chemotherapy and radiotherapy remain vital tools, yet they often damage ...

Todays Updates

Many patients learn they could have cancer in the emergency department

Abdominal and chest pain. Injuries. Breathing difficulty. Infections. Mental health emergencies. Those are some of the most common reasons why people go to the local emergency department.

An understudied type of breast cancer poses a lurking threat

University of Colorado Cancer Center member Matthew Sikora, Ph.D., is a national leader in research into an understudied subtype of breast cancer that's on the rise in American women, is often more difficult to detect than ...

How a new light-based cancer treatment could destroy tumors without harming healthy cells—using LEDs

Cancer treatment has come a long way, but many of today's therapies still come with steep costs: not just financial, but physical and emotional too. Chemotherapy and radiotherapy remain vital tools, yet they often damage ...

Latest News

Immunotherapy has been one of the most promising advancements in cancer treatment. However, consistency in immunotherapy treatment effectiveness remains a formidable challenge. Now, Cancer Center at Illinois member Kun Wang, ...

By analyzing the tumor environment of diffuse large B-cell lymphoma (DLBCL), researchers from The University of Texas MD Anderson Cancer Center have identified seven distinct cellular microenvironments, providing a framework ...

A genomic test co-developed by Mayo Clinic and SkylineDx can identify whether people with melanoma are at low or high risk for cancer in their lymph nodes—a finding that could guide treatment decisions and help many people ...

Cellular changes that appear during melanoma and lead to treatment resistance can be reversed with drugs—potentially opening the door to new or more effective treatments for the deadly disease, according to new Cornell ...

Elironrasib led to meaningful and durable responses in patients with metastatic KRAS G12C-mutated non-small cell lung cancer (NSCLC), including after prior treatment with KRAS G12C inhibitors and in the presence of features ...

Zenocutuzumab (Bizengri), a bispecific antibody that targets human epidermal growth factor receptor 2 (HER2) and HER3, led to responses in more than a third of patients with neuregulin 1 (NRG1)-positive cholangiocarcinoma, ...

News All Time

ADC improves outcomes in advanced triple-negative breast cancer patients ineligible for immune checkpoint inhibitors

Patients with an aggressive form of breast cancer who are not candidates for immune checkpoint inhibitor therapy showed significantly improved progression-free survival when treated with the antibody drug conjugate sacituzumab ...

How multiple sclerosis harms a brain long before symptoms appear

By the time patients start seeking care for multiple sclerosis (MS), the disease has already been damaging their brains for years. But until recently, scientists didn't understand which brain cells were being targeted or ...

Immune-altering drug suppresses tumor-protecting cells and enhances stomach cancer treatment

Working with an international team of collaborators, scientists at Columbia University have found a way to shift the balance of a type of white blood cell inside a stomach tumor, causing the immune system to recognize and ...

New generation of antibody-drug conjugates shows promise in early-stage HER2-positive breast cancer

In a landmark moment at the ESMO Congress 2025, pivotal studies have unveiled compelling evidence that a new class of anti-cancer agents—antibody-drug conjugates (ADCs)—can dramatically improve outcomes for patients with ...

Blood test guides post-surgical immunotherapy for muscle-invasive bladder cancer

Patients with muscle-invasive bladder cancer who test positive for circulating tumor (ct)DNA after surgery to remove the cancer benefit from immunotherapy with atezolizumab compared to placebo whereas ctDNA-negative patients ...

Targeted immunotherapy combination offers hope to older adults with leukemia

Researchers from the Alliance for Clinical Trials in Oncology have found that two targeted immunotherapy drugs lead to high remission rates and long survival with reasonable side effects for older patients with a tough-to-treat ...

Scientists discover how cells protect the skin from inflammatory disease—paving the way for new treatments

Researchers at VIB and Ghent University have uncovered a key mechanism that protects the skin from harmful inflammation. The findings, published in Immunity, could open new avenues for treating chronic skin diseases and other ...

VT3989 continues to show promising early results in patients with advanced mesothelioma

The first-in-class YAP-TEAD inhibitor VT3989 continued to be well tolerated and demonstrated notable initial antitumor activity, particularly in patients with refractory mesothelioma, according to results from a trial led ...

Supercharging immune cells to fight drug resistant bowel cancer

Scientists at University College London have engineered a rare type of immune cell to kill slow-growing bowel cancer cells that are resistant to current therapies, a breakthrough that could lead to new treatments in the future.

'Craters' on surface of melanoma cells mark tumor-killing hotspots, study reveals

New research published in Cell finds the existence of craters on the surface of melanoma cells that serve as immune hubs, becoming major sites for tumor killing. These craters could serve as good markers for immunotherapy ...

Crucial protein enables immune system memory

Researchers at the University of Missouri School of Medicine have recently found that a certain protein may have a large influence on how the immune system functions.

Modified virus boosts cancer vaccine effectiveness in mouse experiments

Could a future vaccine against cancer be made better by an immune-boosting virus? Very likely, say Canadian scientists, who've proven its effectiveness in experiments on mice.

Biomarker analysis reveals clues to long-term survival in glioblastoma patients treated with SurVaxM

Results of a study led by researchers at Roswell Park Comprehensive Cancer Center are shedding light on why some newly diagnosed glioblastoma patients survive longer than others after receiving standard treatment in conjunction ...

Cancer patients' thymic health is linked to their response to immunotherapy 

In cancer patients, the health of the thymus—a key part of the body's immune system—is associated with the outcomes these patients experience after immune checkpoint inhibitor treatment, according to an international ...

How bacteria in tumors drive treatment resistance in cancer

Researchers from The University of Texas MD Anderson Cancer Center have discovered a previously unknown mechanism that explains how bacteria can drive treatment resistance in patients with oral and colorectal cancer. The ...

Child's atopic dermatitis linked to maternal depression scores

Child atopic dermatitis (AD) is associated with higher maternal depression scores, according to a study published online Oct. 5 in the Journal of the American Academy of Dermatology.

Recommended News For You

Researchers discuss HER2-low and HER2-zero in breast cancer

When performed by skilled surgeons, robotic surgery for pancreatic tumors is safe and feasible.

recognizing the mechanism by which the replication of the host cell is outperformed by the skin cancer virus.

FDA Expands Durvalumab Label to Operable Lung Cancer

FDA Greenlights First Engineered Cell Therapy for a Solid Tumor

Congress Ditched Fix to Medicare Doc Pay Cut in Skinny Budget Bill

Unexplained CAR-T Death; Americans Spurn Sunscreen; Improving Diversity in Trials

Recommended Articles For You

Polyposis Syndrome: Causes, Symptoms, and Treatment Options 

Oncology Partnerships: Driving Innovation Through Strategic Collaborations and Pharma Engagement USA 

A New Dawn for Triple-Negative Breast Cancer: Emerging Therapies and the Art of Healing 

Unveiling the Invisible: The Transformative Role of Radiomics in Precision Oncology 

Whats more on Hidoc Dr.

Medical Updates
KOL Videos
Surveys
Events

Daily news to keep you up to date

Gain valuable insights with our in-depth KOL Video discussions

Participate and win cash vouchers

Get updates on the latest events happening around the world
Featured News
Featured Articles
Featured Events
Featured KOL Videos

1.

Early Results for Anorexia Nervosa with Psilocybin.

2.

FDA Bans Red Dye No. 3 From Foods, Ingested Drugs

3.

Academics + Pharma = Big Bucks; New CAR-T Warnings; Patients Seek Cancer Tests.

4.

Rural colon cancer patients face higher risks, but minimally invasive surgery could narrow gap

5.

Short Shrift in Cancer Funding; Bypassing Familiar for Distant; Testing for BRCA.

1.

Unraveling the Mysteries of Burkitt Lymphoma: A New Hope for Treatment

2.

Understanding Lymphedema: Symptoms, Causes, and Treatment 

3.

How EPCORITAMAB is Revolutionizing the Treatment of Cancer

4.

Recombinant ADAMTS13: Advancing Prophylaxis in Congenital TTP Management

5.

Studying Lactic Acid in Pediatric Tumor Microenvironments: Experimental Approaches Explored

1.

International Lung Cancer Congress®

2.

Genito-Urinary Oncology Summit 2026

3.

Future NRG Oncology Meeting

4.

ISMB 2026 (Intelligent Systems for Molecular Biology)

5.

Annual International Congress on the Future of Breast Cancer East

1.

An Eagles View - Evidence-based Discussion on Iron Deficiency Anemia- Panel Discussion IV

2.

A Comprehensive Guide to First Line Management of ALK Positive Lung Cancer - Part II

3.

Pazopanib Takes Center Stage in Managing Renal Cell Carcinoma - Part II

4.

Navigating the Complexities of Ph Negative ALL - Part VIII

5.

Breaking Down PALOMA-2: How CDK4/6 Inhibitors Redefined Treatment for HR+/HER2- Metastatic Breast Cancer

Fastest Growing Medical Platform for Doctors

Address :
Hidoc Dr. Inc. | Delaware C Corp | 1309 Coffeen Ave. Suite 1200, Sheridan WY, 82801

Phone :
+1-415-463-3094

Email :
anishagadia@hidoc.co

Quick Links

Drug DatabaseDrug InteractionDiseases Database
KOL VideosKnowledge HubQuizzes
Medical UpdatesEventsAbout Us

© Copyright 2025 Hidoc Dr. Inc.

Terms & Conditions - LLP | Inc. | Privacy Policy - LLP | Inc. | Account Deactivation
Home
Profile
Login
bot