Early Top-Down Therapy May Modify Course of Crohn’s Disease

Published Date: 23 Feb 2026

Starting biologic therapy at diagnosis, rather than escalating later, may significantly reduce complications and hospitalizations in Crohn’s disease, according to new data.

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A French gynecologist recounts 11 years as Greenland’s lone hospital doctor, where polar nights, isolation, and Inuit hospitality shaped her extraordinary life.

Two groups studied the same cancer mutations in the blood. They agreed on many aspects, including the mechanism at work. But their answers were radically different.

Oral antihistamines appear to be effective in reducing nasal symptoms and improving quality of life compared with placebo in children with allergic rhinitis, a network meta-analysis finds.

The evolution in the types of immunosuppressive therapies used in children and the frequency with which they are prescribed has increased the importance of pretreatment screening for infection risk.

The NHS is rolling out blood matched for red and white cells to kidney transplant patients, potentially averting 100 rejections a year.

Hyponatraemia during the first 72 hours of life is linked to later neurodevelopmental disorders or death in infants with perinatal asphyxia.

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Certain antiphospholipid antibody profiles are associated with increased odds of adverse pregnancy outcomes in women with systemic lupus erythematosus.

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Patients with symptomatic sclerosing mesenteritis often present with abdominal pain and have concurrent autoimmune, malignant, or metabolic disorders.

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