Factor XIa Tied to Benefit Beyond Stroke Prevention

Published Date: 09 May 2026

Results from the OCEANIC-STROKE trial show that the investigational Factor XIa inhibitor, asundexian, not only reduces the recurrent ischaemic stroke risk, but when they do occur, they are less likely to be disabling or fatal.

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Despite early termination, the ANTHEM-HFrEF trial holds important lessons for investigators.

The risk for extrahepatic cancers varies among subgroups of steatotic liver disease, with the highest risk seen in patients with metabolic dysfunction and alcohol-associated liver disease.

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