Novo Nordisk’s Amycretin Demonstrates Superior Weight Loss Versus Placebo

Published Date: 29 Nov 2025

Novo Nordisk’s Amycretin Demonstrates Superior Weight Loss Versus Placebo

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Emerging evidence links prenatal biology and early-life exposures to later obesity risk, suggesting that prevention may need to begin before excess weight develops.

Danish biosolutions maker Novonesis expects results in the second half of 2027 from research ⁠with Novo Nordisk into whether microbiome supplements could provide additional...

Children diagnosed with T1D before age 7 may face a lower risk for long-term chronic complications in the first 20 years post-diagnosis than those diagnosed later in childhood.

Celon Pharma's experimental semaglutide product Reduzek, a generic alternative ⁠to Novo Nordisk's Wegovy and Ozempic, matched the blockbuster weight-loss ⁠drugs in an...

Once-weekly insulin efsitora alfa won NICE backing for adults with type 2 diabetes after trials showed glucose control similar to that with established basal insulins, with fewer injections.

Among adults with type 1 and type 2 diabetes in Denmark, the incidence of CKD declined from 2016 to 2024 even as its prevalence rose, and mortality remained substantially higher in those with CKD.

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Screening for Confidence Tailors GLP-1 Care

Perceived competence — not other factors — best distinguishes weight-loss success with GLP-1 treatment.

Amylyx Drug Cuts Low Blood Sugar Episodes in Bariatric Surgery Patients in Key Trial

Amylyx Pharmaceuticals' experimental drug sharply reduced dangerously low blood sugar episodes in a late-stage trial of patients who ⁠underwent weight-loss surgery, sending...

Diabetes Drug Curbs Weight Gain in Older People With HIV

Metformin, a common diabetes drug, curbs weight gain in older people with HIV over 96 weeks, but the effect reverses after treatment stops, a trial finds.

Semaglutide and Depression: No Clear Link Found

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GI Medicine Is a ‘Fantastic Voyage’: AGA President Cryer

Gastroenterologist Byron L. Cryer, MD, discusses mentorship, NSAID research, difficult patient conversations, and why access to care remains a pressing challenge.

Swapping Soda for Diet Drinks May Not Cut T2D Risk

Swapping sugary drinks for diet drinks is linked to an increased risk for type 2 diabetes, particularly among younger adults and those of non-Dutch origin.

Low-Carb Diet Tied to Healthier Target Weight

In women with overweight or obesity, eating lower carbs is linked to a healthier target weight and lower waist circumference, body fat, and visceral fat but not to the A Body Shape Index.

CGM Metrics Can Improve Prognosis Insights Beyond A1c in T1D

In patients with T1D, certain CGM metrics can provide information on the risk for severe hypoglycemia independent of A1c and add predictive value for diabetic ketoacidosis.

Health Round: Most Air Pollution Exposure in U.S. Pregnancies Is From Wildfires, Study Says

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Prader-Willi Experts Flag Safety Risks Linked to Rare Disease Drug

Experts in Prader-Willi Syndrome on Tuesday raised safety concerns over Neurocrine's drug Vykat XR, citing serious adverse events reported ⁠in patients with the rare genetic...

Role-Play as Patients Helps Docs Manage Diabetes Better

A 1-week, on-site role-play-based program in which physicians simulate patient experiences leads to better A1c control in patients with type 2 diabetes at 6 and 12 months.

Duration and Age Tied to Different Complication Risks in T1D

In patients with childhood onset T1D, a longer diabetes duration is mainly linked to a higher risk for retinopathy, and older age more strongly predicts albuminuria after over 30 years of follow up.

Weekly Somapacitan Effective and Safe in Turner Syndrome

Once-weekly somapacitan is as effective as daily growth hormone in promoting linear growth among treatment-naive girls with Turner syndrome, offering a suitable alternative treatment.

Low-Carb Diets: Modest Wins for Weight, Blood Sugar

Cutting carbs may help adults with overweight or obesity achieve modest weight loss and improve some metabolic markers, but the benefits appear limited and don’t increase with stricter restriction.

Med Op-Ed: Drugs, Obesity, and BMI at a Crossroads

Should the FDA rein in celebrity drug endorsements? Could redefining obesity end up rationing care? And is relying on BMI alone letting patients down?

T2D Medication Patterns Vary by A1c Levels

Type 2 diabetes medication adjustments in older adults vary by A1c levels.

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