An original stem cell study provides insight into Klinefelter syndrome.

Published Date: 05 Apr 2023

Scientists have conducted a first-of-its-kind study in a collaboration between King Abdullah University of Science and Technology (KAUST), King Abdulaziz University, Jeddah (KAU), and King Abdulaziz University Hospital, Jeddah (KAUH).

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Eating out instead of preparing food at home is exacerbating the global obesity epidemic, with half of adults worldwide eating out at least once a week.

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GLP-1 consumer apps can help patients stay on track but have no evidence base; clinical-grade apps can do more but are not accessible to most patients.

Fezolinetant Linked to Enzyme Elevations

Fezolinetant is associated with a hepatic adverse event reporting signal characterized primarily by transaminase elevations rather than clinically overt liver injury.

Study Sheds Light on Burden of Rare Bone Disease in France

Fibrous dysplasia or McCune-Albright syndrome affects approximately 5 per 1,000,000 hospitalised patients in France, with higher rates observed among children and women.

Surgery or Meds for Weight Regain After Sleeve Gastrectomy?

A retrospective study finds that conversion surgery after sleeve gastrectomy produces greater long-term weight loss than obesity medications for recurrent weight gain.

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Chiauranib Slows Platinum-Resistant Ovarian Cancer

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Todays Updates

Chiauranib Slows Platinum-Resistant Ovarian Cancer

The investigational drug extends progression-free survival in a phase 3 trial in patients with platinum-resistant or -refractory ovarian cancer.

Latest News

Eating out instead of preparing food at home is exacerbating the global obesity epidemic, with half of adults worldwide eating out at least once a week.

GLP-1 consumer apps can help patients stay on track but have no evidence base; clinical-grade apps can do more but are not accessible to most patients.

Fezolinetant is associated with a hepatic adverse event reporting signal characterized primarily by transaminase elevations rather than clinically overt liver injury.

Fibrous dysplasia or McCune-Albright syndrome affects approximately 5 per 1,000,000 hospitalised patients in France, with higher rates observed among children and women.

A retrospective study finds that conversion surgery after sleeve gastrectomy produces greater long-term weight loss than obesity medications for recurrent weight gain.

A moderately protein-restricted diet is tied to favorable kidney outcomes in patients with chronic kidney disease stage III or IV, according to a recent retrospective study.

News All Time

PFAS Linked to Lower Bone Density in Youth

Data from the long-running HOME study links higher exposure to certain polyfluoroalkyl substances ‘forever chemicals’ with lower bone mineral density in children and adolescents.

Indigenous-Led Study Targets Transplant Inequities

Researchers will document patient experiences and barriers to care across British Columbia, Alberta, and Saskatchewan.

Weight-Loss Pill Approval Highlights Important Role of PCPs

FDA approval of Eli Lilly’s weight-loss pill on April 1 shows the fast-changing landscape for weight loss, obesity medications.

Thyroid Aging Patterns Can Predict Mortality Risk

Thyroid function changes modestly with age but shows greater variability from age 65 years onward, and distinct patterns of thyroid function change are linked to an increased risk for mortality.

Curcumin Supplementation May Help Ease Depression

Curcumin, the primary active compound in the spice turmeric, was associated with significant reduction in depressive symptoms in new research that has been characterized as ‘clinically meaningful.’

EMA Panel Backs Weekly Hormone for Child Growth Disorders

European regulators recommend expanding once-weekly growth hormone therapy to include children born small for gestational age and those with Noonan syndrome, potentially reducing injection burden.

Europe Moves Closer to New Retinal Disease Biosimilar

A new anti-VEGF biosimilar has moved closer to European approval for several vision-threatening retinal diseases, including choroidal neovascularization.

Dexcom Warns Patients as Stolen Glucose Sensors Hit the Market

Medical device maker Dexcom said on Tuesday some of its glucose ⁠sensors slated for destruction were instead stolen and sold, prompting the company ⁠to warn users not to use...

Weight Loss Alone May Not Prevent T2D in Some Patients

Prediabetes management often emphasizes weight loss, but a long-term follow-up study found that for some older adults, thinner isn’t always better.

Telephone Weight-Loss Coaching Pays Off in Breast Cancer

Among women with overweight or obesity and early breast cancer, those with the poorest physical function and mental health at baseline appear to benefit the most from telephone weight-loss coaching.

GLP-1s Tied to Weight Loss in Real-World Rheumatologic Care

Semaglutide and tirzepatide use is rising among patients with rheumatic and musculoskeletal diseases and is linked to meaningful 1-year weight loss, especially in tirzepatide users.

FRAX Predicts Surgery Benefit in Hyperparathyroidism

The Fracture Risk Assessment Tool predictions suggest patients who don’t meet guideline criteria for parathyroidectomy may nevertheless benefit from the surgery.

Tirzepatide Yields Early Weight Loss, Later Plateau

Modeling finds marked early weight loss with tirzepatide that later plateaus as appetite returns and energy expenditure decreases, and discontinuation of the drug is linked to partial weight regain.

Serum Acylcarnitines May Predict Kidney Decline in Diabetes

Specific serum acylcarnitine levels are linked to faster kidney function decline in type 2 diabetes and can help improve the prediction of patients at highest risk for rapid decline.

Stigma Negatively Affects Postbariatric Outcomes

Weight bias, stigma, and discrimination are linked to poorer mental health and weight outcomes after bariatric surgery, although the long-term physical effects remain understudied.

The Sweetener Trap: Are Sugar Alternatives Backfiring?

Emerging evidence suggests some sugar substitutes may affect metabolism, gut microbiome, and cardiovascular health more than previously recognized.

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