An original stem cell study provides insight into Klinefelter syndrome.

Published Date: 05 Apr 2023

Scientists have conducted a first-of-its-kind study in a collaboration between King Abdullah University of Science and Technology (KAUST), King Abdulaziz University, Jeddah (KAU), and King Abdulaziz University Hospital, Jeddah (KAUH).

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Single-dose radiation before surgery can eradicate breast cancer

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When labor begins, the uterus must coordinate rhythmic, well-timed contractions to deliver the baby safely. While hormones such as progesterone and oxytocin are key contributors to that process, scientists have long suspected ...

Shilpa Gajarawala struggled with hot flashes, night sweats, sleep problems and brain fog. But given her history of breast cancer, treating these menopausal symptoms with hormone therapy wasn't an option.

The U.S. Food and Drug Administration (FDA) is eliminating the prominent "black box" warnings on many hormone replacement therapy (HRT) medications, signaling a major shift in how the treatment is viewed for menopausal women.

The internet, libraries and bookshops are full of plans and advice on how to lose weight, from fad diets to intense exercise routines. But there could be another route to keeping the pounds away, and that's with a gut bacterium ...

In a discovery that could shift labor and delivery practices around the world, researchers at Michigan State University have found that the effectiveness of oxytocin—a common medication used to induce or speed up labor—depends ...

The European Society of Endocrinology (ESE) has published a Revised Clinical Practice Guideline for the Treatment of Chronic Hypoparathyroidism in Adults in the European Journal of Endocrinology.

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Estrogen's role in boosting dopamine and cognition: Experiments uncover how hormones influence learning

Researchers have long established that hormones significantly affect the brain, creating changes in emotion, energy levels, and decision-making. However, the intricacies of these processes are not well understood.

Cutting key amino acids from mouse diets triggers weight loss through heat burning

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Routine use of metabolic drug recommended for all kidney function levels

The results of two large-scale studies demonstrate that sodium-glucose co-transporter 2 (SGLT2) inhibitors significantly reduce the risk of kidney disease progression, hospitalization, and death in people with and without ...

Urolithin A nudges aging immune cells toward a youthful profile in 28 days

An international research team focused on aging reports that urolithin A at 1,000 mg per day shifted human immune profiles toward a more naive-like, less exhausted CD8+ state and increased fatty acid oxidation capacity, with ...

Why morning exercise feels so hard

Your alarm goes off. Somehow you manage to get dressed, drag yourself to the gym, and start squatting.

Urinary albumin-creatinine ratio better measures risk for kidney failure

The urinary albumin-creatinine ratio (UACR) is more strongly associated with kidney failure than the urinary protein-creatinine ratio (UPCR), according to research published online Nov. 4 in the Annals of Internal Medicine.

Missing enzyme may explain impaired bone growth

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Q&A: Managing menopause after cancer

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Widely used pesticides may lower sperm count

Contemporary agricultural practices make it difficult to prevent consuming chemicals and potentially causing harm to the body.

Insights from worms could help scientists harness the power of dietary restriction for longevity

The pursuit of a longer life may currently be trending for tech bros, but the notion of a fountain of youth, or even immortality, has intrigued people for millennia. Yet, some of the more evidence-based methods to increase ...

Triggering cell death in metastatic melanoma may pave the way for new cancer treatments

Metastatic melanoma cells that have spread to lymph nodes survive by relying on a protein called ferroptosis suppressor protein 1 (FSP1)—a surprising metabolic dependency that could open the door to a new class of cancer ...

Missing a common protein could affect how muscles respond to testosterone

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New research challenges simplistic views on detransition

As access to gender-affirming care has expanded in recent years, public and clinical understandings of gender transition and detransition have remained limited and highly politicized. Anecdotal reports of detransition have ...

Chaperone-mediated autophagy prevents loss of brown adipose tissue activity during aging

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Yes, you can be intolerant to fruit and veg

For most people, eating a wide variety of fruit and vegetables is the cornerstone of a healthy diet.

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