An original stem cell study provides insight into Klinefelter syndrome.

Published Date: 05 Apr 2023

Scientists have conducted a first-of-its-kind study in a collaboration between King Abdullah University of Science and Technology (KAUST), King Abdulaziz University, Jeddah (KAU), and King Abdulaziz University Hospital, Jeddah (KAUH).

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Todays Updates

Residency Reverse: When the Patient's Home Is the Office

Home visits — once common and now resurging — flip the dynamic, as the clinician becomes a guest in the patient's home. Experts say as both learn more about each other than is possible in-office, trust can build.

Hidden Body Fat Threatens Male Fertility

Higher body fat percentage, rather than BMI, is associated with reduced sperm count and disrupted reproductive hormone levels in men.

The Dose Is Too High: Rethinking TKI Dosing

Standard TKI doses are often too high for long-term care. Dr Mark Kris shares his strategy for smart dose reductions that protect patient outcomes.

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Cure rates are climbing, and so is the complexity of getting there. Dr Yara Abdou takes a closer look at optimizing HER2+ early-stage breast cancer therapy.

What I Wish I Knew Before Starting a Direct Primary Care

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Latest News

A machine learning model improves prediction of type 1 diabetes risk compared with a conventional genetic risk model, particularly in people without high-risk human leukocyte antigen haplotypes.

Circulating endotrophin rises with fat gain and falls with fat loss, showing promise as a biomarker of body fat changes and a potential target for reducing obesity-linked health risks.

An analysis of nearly 33 million continuous glucose monitoring readings links hotter temperatures to more frequent hypoglycemia in adults with type 1 diabetes.

Women with obesity who completed supervised physical activity programs — whether face-to-face or digital — showed marked improvements in self-esteem and body image, with most gains emerging in the first month and persisting 3 months later.

Brazil's health regulator said ⁠it approved five new injectable GLP-1 drugs for diabetes and obesity treatment, ⁠following the expiration ⁠of Ozempic’s patent in ‌the country.

Consensus document from three European societies covers nutritional, functional, and psychological considerations for incretin-based therapies in adults.

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Obesity Phenotype Predicts Tirzepatide Super Responders

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Extreme Obesity Tied to Higher Mortality

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Short Stature: Is Genetic Testing Transforming Diagnosis?

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Review of Exercise for Hip OA Suggests Minimal Benefits

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Thyroid Abnormalities Often Normalize in Pregnancy

Most pregnant women initially testing positive for subclinical hypothyroidism or hypothyroxinemia do not sustain abnormal thyroid function throughout pregnancy.

Protein, Not Calcium, Key to Osteoporosis Treatment Benefits

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Desire to Lose Weight Linked to Unhealthy Behaviors

More than 60% of American adults want to weigh less, and those who do are significantly more likely to skip meals, use non-prescription supplements, or engage in purging behaviors.

Obesity and Cognitive Problems: Understanding the Connection

One can lead to the other. There are a number of reasons why.

Diet Program May Not Match Knee Surgery in Knee OA & Obesity

In patients with obesity and knee osteoarthritis eligible for knee arthroplasty, an intensive dietary weight-loss program is clinically inferior to surgery for patient-reported pain and function.

Increasing GLP-1 Use Raises Muscle Loss Concerns

Incretin mimetic therapy for obesity may reduce muscle mass and bone mineral density, but its effects on physical function and the risk for fractures in older adults remain uncertain.

Spermidine Intake Tied to Liver Health in Obesity and MetS

An increase in dietary spermidine intake over 1 year is associated with improvements in hepatic function and cardiometabolic health in older adults with overweight or obesity and metabolic syndrome.

USG Detects Vagus Nerve Atrophy in Parkinson's Disease

Ultrasound imaging reveals structural changes in the vagus nerve of patients with Parkinson's disease in a meta-analysis.

SGLT2-GLP-1 Combo Little Better Than Monotherapy in T2D

Using both SGLT2 inhibitors and GLP-1 receptor agonists is no more effective than using either drug alone in patients with type 2 diabetes, a new meta-analysis suggests.

Mindfulness-Based Eating Improves Anxiety, Eating Behavior

A mindfulness-based eating intervention improved anxiety, depression, and eating behaviors in adults with obesity and generalized anxiety disorder.

5 Common Lab Results: Why Context Matters

Common laboratory tests can mislead when interpreted without clinical context, highlighting why appropriate test selection matters as much as the results themselves.

Lilly Announces More Next-gen Obesity Drug Data, Plans Q1 2027 FDA Application

Eli Lilly said on Thursday that two more Phase 3 trials of its experimental obesity drug retatrutide showed positive results and it plans to submit ⁠an application to the...

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