Feb 06 2026 This Week in Cardiology

Published Date: 20 Apr 2026

Problems with the PREVENT score, a breakthrough in lipid-lowering therapy, a surprising benefit in stroke care, and more thoughts on statins and preventive care of heart disease are the topics John Mandrola, MD, discusses in this week’s podcast.

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ESC 2026: Clinical Trials That Could Change Practice

Which ESC 2026 trials matter most? An expert preview singles out the studies most likely to open new therapeutic avenues or challenge current practice.

Microbiome ‘Leak’ From Mouth to Gut Can Flag GI Cancer

Scientists identify a ‘microbial transmission’ signature — oral bacteria colonizing the gut — that flags gastrointestinal cancers with greater accuracy than conventional stool testing.

Nurse Practitioners the Key to Diagnosing Ketamine Cystitis

Ketamine cystitis causes irreversible damage but is often caught too late.

Key Clinical Challenges in Diverticulitis: New ACG Guideline

A new ACG guideline on the management of colonic diverticulitis provides recommendations on key issues including use of antibiotics and diet.

Unpartnered Status Tied to Low Binge Drinking Risk in Women

Being unpartnered in later life is linked to higher odds of alcohol abstinence among older adults and lower odds of binge drinking among women, without mediation by depression or loneliness.

Chemo Drug Exposure Linked to CAR T-Cell Therapy Outcomes

Optimal fludarabine exposure during lymphodepletion is associated with improved progression-free survival after CAR T-cell therapy in patients with relapsed/refractory large B-cell lymphoma.

Todays Updates

Emerging ADC-Based Strategies in mNSCLC: Interpreting Clinical Evidence and Implications for Practice

Emerging ADC-Based Strategies in mNSCLC: Interpreting Clinical Evidence and Implications for Practice

Bridging the Gap to CAR T-Cell Therapy for Relapsed/Refractory Multiple Myeloma: An Expert TheraTalk

Bridging the Gap to CAR T-Cell Therapy for Relapsed/Refractory Multiple Myeloma: An Expert TheraTalk

Can a Betting Market Offer Hope to a Cancer Patient?

As we embrace the power of collective knowledge, we must remember that numbers are just numbers

Rewriting the Future of Medicine; Cancer Cost Burden; Mental Health Toll of Cancer

News, features, and commentary about cancer-related issues

Biden's Bedtime Cancer Symptom; Top Cancer Hospitals; FDA Panel to Review MCED Test

News, features, and commentary about cancer-related issues

Liposomal Chemo Combination No Better Than Standard Induction in Pediatric AML

"This specific formulation of daunorubicin and cytarabine is not the right choice," experts said

Post-Transplant Outcomes in Hodgkin Lymphoma Improved Over Time

Improvements primarily driven by reduction in incidence of relapse

Todays Updates

Emerging ADC-Based Strategies in mNSCLC: Interpreting Clinical Evidence and Implications for Practice

Emerging ADC-Based Strategies in mNSCLC: Interpreting Clinical Evidence and Implications for Practice

Bridging the Gap to CAR T-Cell Therapy for Relapsed/Refractory Multiple Myeloma: An Expert TheraTalk

Bridging the Gap to CAR T-Cell Therapy for Relapsed/Refractory Multiple Myeloma: An Expert TheraTalk

Can a Betting Market Offer Hope to a Cancer Patient?

As we embrace the power of collective knowledge, we must remember that numbers are just numbers

Rewriting the Future of Medicine; Cancer Cost Burden; Mental Health Toll of Cancer

News, features, and commentary about cancer-related issues

Biden's Bedtime Cancer Symptom; Top Cancer Hospitals; FDA Panel to Review MCED Test

News, features, and commentary about cancer-related issues

Liposomal Chemo Combination No Better Than Standard Induction in Pediatric AML

"This specific formulation of daunorubicin and cytarabine is not the right choice," experts said

Post-Transplant Outcomes in Hodgkin Lymphoma Improved Over Time

Improvements primarily driven by reduction in incidence of relapse

Latest News

Which ESC 2026 trials matter most? An expert preview singles out the studies most likely to open new therapeutic avenues or challenge current practice.

Scientists identify a ‘microbial transmission’ signature — oral bacteria colonizing the gut — that flags gastrointestinal cancers with greater accuracy than conventional stool testing.

Ketamine cystitis causes irreversible damage but is often caught too late.

A new ACG guideline on the management of colonic diverticulitis provides recommendations on key issues including use of antibiotics and diet.

Being unpartnered in later life is linked to higher odds of alcohol abstinence among older adults and lower odds of binge drinking among women, without mediation by depression or loneliness.

Optimal fludarabine exposure during lymphodepletion is associated with improved progression-free survival after CAR T-cell therapy in patients with relapsed/refractory large B-cell lymphoma.

News All Time

Higher Body Fat Tied to Lower Kidney Function in Adults

Higher body and fat mass are associated with lower kidney function, particularly in women and adults older than 40 years, whereas greater fat-free mass is linked to better eGFR.

Youth Mental Health Model Shifts Care to Community Settings

A multiservice model that also supports youth with complex mental health needs shows that an inclusive approach offers a return on investment.

Poor Mental Health Tied to Risk for Drug Use Disorder

Poor mental health in US adults is linked to a significantly higher risk for a drug use disorder, with patterns often shaped by ADHD status, new research shows.

Active Surveillance Rises as Focal Therapy Persists

Surveillance has surged for favorable-risk prostate cancer, but focal therapy remains in use despite limited evidence and limited guideline support.

Ankle Strength Not Linked to Joint Hypermobility in Children

Ankle strength shows no clear association with foot posture or general joint hypermobility in children, with only weak links to lower limb hypermobility.

Symptoms May Signal Prostate Cancer in Primary Care

Patients presenting to primary care with prostate symptoms are more likely to be diagnosed with clinically significant prostate cancer than those without recorded symptoms.

Can Deep Brain Stimulation Finally Deliver for Depression?

Nearly a decade ago, a landmark trial of deep brain stimulation for depression failed to show efficacy. Now researchers are trying again, and the stakes are higher than ever.

Imported Eggs Prime Suspect in Salmonella Outbreak

A Salmonella outbreak in the UK has left hundreds ill, with one associated death, and may be linked to imported eggs, say health officials.

Daily Zinc Reduces Infections in Sickle Cell Anemia

Zinc deficiency is common in people with sickle cell disease. Now a trial in Uganda suggests daily supplements can prevent infections in young children with the disease.

Bariatric Same-Day Discharge Criteria Lack Consensus

A systematic review finds that most studies on same-day discharge after bariatric surgery use inconsistent patient selection and discharge definitions, preventing reliable evidence synthesis.

Digital Health: Is Innovation Widening the Equity Gap?

Digital health can improve access, but gaps in technology, digital skills, and infrastructure may leave vulnerable groups behind as adoption expands across healthcare.

Case of a Man With Subclavian Steal Syndrome

A man with arm pain, asymmetric blood pressure, and weakness was found to have overlapping vascular and cervical spine disease complicating the diagnosis.

What Influencers Get Wrong about Diet and Gut Health

Your patients hear these claims online. Here's what the evidence actually shows.

The Challenge of Diagnosing ADHD in Adults

Inattention doesn't necessarily mean ADHD. Dr Zebib Abraham explains the complexities of evaluating adults and what clinicians should consider before making a diagnosis.

Navigating Cancer Screening Without the USPSTF

Without USPSTF guidance, how should primary care approach cancer screening? Dr Kenny Lin reviews key updates in cervical, colorectal, and lung cancer protocols.

Telemedicine Remains Relevant in Pediatric Care

The use of telemedicine in child primary care reduces from pandemic highs to 6% by 2024.

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Jazz Seeks Second-Line Lurbinectedin SCLC Withdrawal

MGRS Relapse-Free Survival Better With Maintenance Therapy

Radiation from CT scans could account for 5% of all cancer cases a year, study suggests

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