Neoadjuvant chemotherapy less commonly used in breast cancer

May 22 2026 This Week in Cardiology

Three more digoxin trials, yet another GLP-1 drug on the horizon, vagal nerve stimulation, trial inside baseball, and more on lipid guidelines are the topics John Mandrola, MD, discusses in this week’s podcast.

Does Surgery Type Matter for Young Women With High-Risk BC?

Younger women with high-risk breast cancer often opt for mastectomy, but it may not improve survival or reduce recurrences versus breast-conserving surgery.

Ask the HF Expert: Guideline-Directed Medical Therapy

Chief Cardiology fellow Yash Varma asks HF expert Ileana Piña for tips on when patients are stable to discharge on guideline-directed medical therapy and if it’s ever ok to de-escalate.

Do Smokers Need to Quit Before Lung Cancer Surgery?

Patients who still smoke heading into lung cancer surgery have a higher complication rate than those who have quit — but their mortality risk is no different, a large retrospective study finds.

Adrian Harris: Why Oncology Must Look Beyond Cancer Cells

Many promising therapies fail because of poor patient selection; Harris warns that only about one third of tumors are truly hypoxic, underscoring the need for precise biomarkers in trials.

‘Impossible’ Now Possible: Making Brain Tissue Transparent

Researchers used a blood protein wash to render brain tissue transparent down to 700 µm, witnessing live-firing activity without killing a single neuron.

AstraZeneca's Imfinzi With Pre-surgery Drug Boosts Survival in Bladder Cancer Trial

AstraZeneca said on Thursday that a late-stage trial of Imfinzi, ⁠combined with a targeted therapy prior to a surgery, showed significantly ⁠improved survival rate in...

STS: Society of Thoracic Surgeons

Jehovah's Witnesses Transfusion Policy Now Allows Storage, Use of One's Own Blood

"I don't think it goes far enough, but it's a significant change," said one former member

Nobel-Winning Doctor Dies; 'Buffy' Star's Heart Defect; Cyberattack Delays Surgeries

Health news and commentary gathered by MedPage Today staff

How Secretive Traditional Circumcision Rites Are Responsible for Dozens of Deaths

At least 48 boys and young men died during initiation ceremonies in South Africa

Are We Missing Tumors When Using Antibiotics Alone for Appendicitis?

Study address key concern with nonoperative management of appendicitis

3 Medical Schools Under Investigation; 9 Sick in Outbreak; 5-Second Rule in the OR?

Health news and commentary gathered by MedPage Today staff

Trader Joe's Recall; 450 Hospitals May Close or Cut Services; 'Rib Remodeling' Trend

Health news and commentary gathered by MedPage Today staff

From the Operating Room to the Oscars

A Q&A with a physician consultant for the Academy Award-winning short, "All the Empty Rooms"

These Women Had Their Breasts Removed to Thwart Cancer. Then Came the Pain.

A look at "post-mastectomy pain syndrome"