Neoadjuvant chemotherapy less commonly used in breast cancer

Published Date: 02 Mar 2023

Most women will have breast cancer surgery first if the initial consultation is with a surgeon. This study has been published as a preprint and has not yet been peer-reviewed.

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Three more digoxin trials, yet another GLP-1 drug on the horizon, vagal nerve stimulation, trial inside baseball, and more on lipid guidelines are the topics John Mandrola, MD, discusses in this week’s podcast.

Younger women with high-risk breast cancer often opt for mastectomy, but it may not improve survival or reduce recurrences versus breast-conserving surgery.

Chief Cardiology fellow Yash Varma asks HF expert Ileana Piña for tips on when patients are stable to discharge on guideline-directed medical therapy and if it’s ever ok to de-escalate.

Patients who still smoke heading into lung cancer surgery have a higher complication rate than those who have quit — but their mortality risk is no different, a large retrospective study finds.

Many promising therapies fail because of poor patient selection; Harris warns that only about one third of tumors are truly hypoxic, underscoring the need for precise biomarkers in trials.

Researchers used a blood protein wash to render brain tissue transparent down to 700 µm, witnessing live-firing activity without killing a single neuron.

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