The identification of novel genes that play a part in fatal heart defects.

Published Date: 21 Jul 2023

Researchers from Sanford Burnham Prebys have discovered new genes by identifying the genes in patients and examining their effects in fruit flies.

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Latest News

A pediatric study from Argentina suggests that AKI during DKA can leave lasting renal damage, reinforcing the need for closer kidney monitoring.

Experts from physics, biology, and medicine met to test whether aging can be mapped with quantitative models that may one day aid clinical care.

Intensive blood pressure-lowering treatment after spontaneous intracerebral hemorrhage was linked to significantly reduced recurrent stroke risk, a meta-analysis shows.

Nearly 80% of young adults are found to have risk factors for cardiovascular-kidney-metabolic syndrome, which is tied to poor heart health, including risk for carotid arterial injury.

No trial has tested starting all four HFrEF drugs at once. What the speed evidence actually supports, where guidelines split, and how to close the implementation gap.

As new Medicaid work mandates start to take effect, patients in some states are asking physicians for waivers, saying they’re too sick or disabled to work. But rules for granting waivers are confusing.

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NOACs Tied to Slower Cognitive Decline in Comorbid AF and AD

Non-vitamin K oral anticoagulant use was associated with modestly slower cognitive decline and lower risks for death and stroke in adults with comorbid Alzheimer’s disease and atrial fibrillation.

Acromegaly-Associated Diabetes Tied to Cardiovascular Issues

Patients with acromegaly-associated diabetes face a higher risk for cardiovascular morbidity, but not mortality, than those with type 2 diabetes.

Can Anticoagulant Alone Lower Bleeding in Coronary Syndrome?

Oral anticoagulation monotherapy is linked to a lower risk for major bleeding in patients with stable chronic coronary syndrome who require long-term anticoagulation therapy.

Deep Dive: SGLT2 Inhibitors: Indication, Not Mechanism, Decides

Six agents share a mechanism, but only two carry heart failure and CKD indications independent of diabetes status. Here is how to tell them apart.

AI Adoption Soars Among UK GPs, but Confidence Doesn't

Use of AI has more than doubled in a year, but survey authors say GPs remain unsure how it will reshape the profession.

Pachychoroid Disease Progression Remains Low

Most eyes with pachychoroid features maintained their subtype over 2 years, with progression to pachychoroid neovasculopathy developing in only a small fraction of eyes.

Obesity Class III Linked to Death Risk in Younger Adults

Younger adults with severe obesity face significantly increased risk for mortality, while older adults show minimal differences across obesity classes.

Integrase Inhibitors Safe for Heart in HIV Patients

A Swiss study tracking thousands of people with HIV found no long-term cardiovascular penalty when switching to integrase inhibitor-based therapy, though a small early-year uptick in events warrants clinical attention.

Mild Tremor Tied to Cognitive Decline in Seniors

Even subtle hand tremor in older adults may signal more than just a benign motor quirk — new population data reveal an unexpected cognitive connection.

Dapagliflozin Reduces AKI After Cardiac Surgery

Four doses of the SGLT2 inhibitor dapagliflozin reduce acute kidney injury risk after elective cardiac surgery, with a low incidence of ketoacidosis.

Cefadroxil Effective for Gram-Positive Bacteremia

Oral cefadroxil shows comparable outcomes to intravenous and alternative oral regimens in treating gram-positive bloodstream infections, a recent study shows.

Dexrazoxane May Preserve LV Function in Cancer Survivors

Researchers analyzed echocardiographic data from patients who received dexrazoxane before doxorubicin as part of their treatment for cancer in childhood.

Photon-Counting CT Boosts Stent Fracture Detection

A phantom study shows that photon-counting detector CT significantly improves the detection of visceral endovascular stent fractures compared with conventional CT.

Postpartum Health Coaching Boosts Blood Pressure Control

Health coaching may help close a critical gap in care after a hypertensive pregnancy.

Five Steps to Earlier Heart Failure Detection

Heart failure often hides behind vague complaints. These five primary care steps can help spot it earlier and guide faster, evidence-based treatment.

How to Talk About Exercise When Weight Loss Is Off the Table

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