SGLT2-GLP-1 Combo Little Better Than Monotherapy in T2D

Published Date: 25 Jul 2026

Using both SGLT2 inhibitors and GLP-1 receptor agonists is no more effective than using either drug alone in patients with type 2 diabetes, a new meta-analysis suggests.

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In patients with obesity and knee osteoarthritis eligible for knee arthroplasty, an intensive dietary weight-loss program is clinically inferior to surgery for patient-reported pain and function.

Incretin mimetic therapy for obesity may reduce muscle mass and bone mineral density, but its effects on physical function and the risk for fractures in older adults remain uncertain.

An increase in dietary spermidine intake over 1 year is associated with improvements in hepatic function and cardiometabolic health in older adults with overweight or obesity and metabolic syndrome.

Ultrasound imaging reveals structural changes in the vagus nerve of patients with Parkinson's disease in a meta-analysis.

A mindfulness-based eating intervention improved anxiety, depression, and eating behaviors in adults with obesity and generalized anxiety disorder.

Common laboratory tests can mislead when interpreted without clinical context, highlighting why appropriate test selection matters as much as the results themselves.

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